转lncRNA-GTL2对小鼠肠道微生物菌群组成的影响

doi:10.16431/j.cnki.1671-7236.2016.10.016

Abstract

Abstract:

This research was aimed to study whether the lncRNA would have effects on the structure and constitution of the intestinal microbial colonies in mice.High throughout sequencing was used to sequence and analyze the intestinal microbial colonies in both transgenic and non-transgenic mice of three months old.We conducted comparison and t-test at the level of phylum and genus.The result showed that transferred into long non-coding RNA genes GTL2 (lncRNA-GTL2),the mouse intestinal microbial colony structure and composition had no significant differences in the overall,within the same gender,but there were individual differences.Therefore,this study didn't find that long non-coding RNA transfered had a significant impact on the intestinal microflorain the phylum and genus level.

Key words: transgenic; lncRNA-GTL2; high-throughput sequencing; intestinal microorganisms

CLC Number:

FAN Xin-hao, WANG Zi-shuai, LIANG Guo-ming, YANG Ya-lan, LI Kui, SONG De-gui, TANG Zhong-lin. Effects of lncRNA-GTL2 Transgenosis on Gut Microbiota Composition in Mice[J]. , 2016, 43(10): 2621-2627.

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Effects of lncRNA-GTL2 Transgenosis on Gut Microbiota Composition in Mice

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