China Animal Husbandry and Veterinary Medicine ›› 2020, Vol. 47 ›› Issue (1): 98-106.doi: 10.16431/j.cnki.1671-7236.2020.01.012

• Genetics and Breeding • Previous Articles     Next Articles

Research Advance on Application of Chip Technology in Livestock and Poultry Breeding

MA Lina1, LIU Yongjin2, WANG Jin1, ZHAO Zhengwei1, MA Qing1   

  1. 1. Research Center of Grass and Livestock, Ningxia Academy of Agriculture and Forestry Sciences, Yinchuan 750002, China;
    2. Agricultural Institute of Survey and Design of Ningxia, Yinchuan 750002, China
  • Received:2019-04-10 Online:2020-01-20 Published:2020-01-17

Abstract: There are abundant resources of livestock and poultry breeds in China,and there are many good trait genes.Unfortunately,these fine trait genes have not been fully utilized.Therefore,the development and utilization of genetics and resources at the genetic level is an important direction for improving economic traits of domestic animal genetics resources.The traditional pedigree selection method played a vital role in breeding while it also has shortcomings such as low accuracy and long breeding cycle.With the rapid development of molecular biology,advanced genome sequencing and gene typing technology have pushed the innovation of livestock and poultry breeding methods.The efficiency of genetic detection has been dramatically improved from the low-throughput,time-consuming restriction fragment polymorphism (RFLP) markers in the past to the single nucleotide polymorphism (SNP) with high-throughput and high density.Genotyping based on chip was widely used in research and breeding practice,becoming a new technology and hotspot in livestock and poultry breeding.In this review,the research and application of SNP chip technology in livestock and poultry breeding,its technical advantages,existing problems,challenges and application prospects are summarized.The paper showed that gene chip technology would become an important basic technology in molecular breeding of livestock and poultry,and play an important role in the rapid development of livestock and poultry breeding industry,promoting the genetics progress of livestock and poultry breeding in China,and enhancing the scientific and technological competiveness of livestock and poultry breeding industry in China.

Key words: chip technology; SNP; high-throughput sequencing; animal breeding

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