α-倒捻子素对肉鸡生长性能、免疫功能、抗氧化能力和解毒功能的影响

doi:10.16431/j.cnki.1671-7236.2025.03.014

摘要/Abstract

摘要： 【目的】研究基础饲粮中添加不同水平的α-倒捻子素对黄羽肉鸡生长性能、免疫功能、抗氧化能力和解毒功能的影响，为其在肉鸡上的应用提供依据。【方法】900只1日龄麻黄肉母雏根据体重一致原则分为6个处理组，每个组6个重复，每个重复25只鸡。6个处理分别在基础饲粮中添加0、15、30、60、120和240 mg/kg α-倒捻子素。试验期54 d。每重复于试验结束当天挑选接近平均重的1只鸡采血、屠宰，分离血浆测定细胞因子含量和抗氧化指标，采集肝脏测定抗氧化和解毒功能相关指标。【结果】①肉鸡体重和平均日增重随α-倒捻子素添加水平的升高呈线性和二次曲线升高(P＜0.05)。不同处理组之间肉鸡平均日采食量、料重比和死淘率均无显著差异(P＞0.05)。②饲粮添加不同水平的α-倒捻子素显著影响肉鸡血浆白细胞介素-1β(IL-1β)、IL-6、IL-10和丙二醛(MDA)含量(P＜0.05)，且随α-倒捻子素添加水平的升高，IL-1β、IL-6和MDA含量均呈线性和二次曲线降低(P＜0.05)，IL-10含量呈线性和二次曲线升高(P＜0.05)。③饲粮添加不同水平的α-倒捻子素显著影响肉鸡肝脏MDA含量以及总超氧化物歧化酶(T-SOD)和谷胱甘肽-S转移酶(GSH-ST)活力(P＜0.05)，且随α-倒捻子素添加水平的升高，MDA含量呈线性和二次曲线降低(P＜0.05)，T-SOD活力呈线性和二次曲线升高(P＜0.05)，GSH-ST活力呈线性升高(P＜0.05)。【结论】饲粮添加α-倒捻子素可改善1～54日龄黄羽肉鸡生长性能，提高免疫功能、抗氧化能力和解毒功能。以体重和平均日增重为主要评价指标、依据二次曲线模型估测，饲粮中α-倒捻子素的适宜添加水平分别为188和156 mg/kg。

关键词: α-倒捻子素; 黄羽肉鸡; 生长性能; 免疫功能; 抗氧化能力; 解毒功能

Abstract: 【Obiective】 The experiment was conducted to investigate the effects of different levels of α-mangostin in basic diet on growth performance,immune function,antioxidant capacity and detoxification function of Yellow-feathered broilers,and to provide evidence for its application in broilers.【Method】 A total of 900 1-day-old Ephedra broiers (female) were divided into 6 treatment groups with 6 replicates per group and 25 broilers per replicate.The diets in 6 treatment groups were supplemented with 0,15,30,60,120,and 240 mg/kg α-mangostin in the basal diet, respectively.The experiment lasted for 54 d.One broiler weighted close to the average body weight was selected from each replicate for blood collection and slaughter on the end of experiment,plasma was separated to determine cytokine content and antioxidant index,liver was collected to determine antioxidant and detoxification function related index.【Result】 ①The body weight and average daily gain of broilers increased linearly and quadratically with the increase of α-mangostin supplemental level (P＜0.05).There were no significant differences in average daily feed intake,feed to gain ratio and mortality rate of broilers among different treatment groups (P＞0.05).②The contents of interleukin-1β (IL-1β),IL-6,IL-10 and malondialdehyde (MDA) in plasma of broilers were significantly affected by different α-mangostin supplemental levels (P＜0.05),and the contents of IL-1β,IL-6 and MDA were linearly and quadratically decreased with the increase of α-mangostin supplemental levels (P＜0.05),IL-10 content increased linearly and quadratically (P＜0.05).③Dietary supplemental different levels of α-mangostin significantly affected the liver malondialdehyde (MDA) content,total superoxide dismutase (T-SOD) and glutathione S transferase (GSH-ST) activities of broilers (P＜0.05),and with the increase of α-mangostin supplemental levels,the MDA content was linearly and quadratically decreased (P＜0.05),T-SOD activity increased linearly and quadratically (P＜0.05),GSH-ST activity increased linearly (P＜0.05).【Conclusion】 Dietary α-mangostin could improve growth performance,immune function,antioxidant capacity and detoxification function of Yellow-feathered broilers aged 1 to 54 days.Using the body weight and average daily gain as main evaluation indexes,according to the quadratic curve model,the optimal supplemental levels of α-mangostin in diet were 188 and 156 mg/kg, respectively.

Key words: α-mangostin; Yellow-feathered broilers; growth performance; immune function; antioxidant capacity; detoxification function

中图分类号:

S816.7

范秋丽, 陶正国, 李辉, 苟钟勇, 王一冰, 林厦菁, 叶金玲, 蒋守群. α-倒捻子素对肉鸡生长性能、免疫功能、抗氧化能力和解毒功能的影响[J]. 中国畜牧兽医, 2025, 52(3): 1123-1130.

FAN Qiuli, TAO Zhengguo, LI Hui, GOU Zhongyong, WANG Yibing, LIN Xiajing, YE Jinling, JIANG Shouqun. Effects of α-mangostin on Growth Performance,Immune Function, Antioxidant Capacity and Detoxification Function of Broilers[J]. China Animal Husbandry and Veterinary Medicine, 2025, 52(3): 1123-1130.

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