[1] XU D,WANG Y,ZHANG X,et al.Dietary valine/isoleucine ratio impact carcass characteristics,meat edible quality and nutritional values in finishing crossbred Duroc×Landrace×Yorkshire pigs with different slaughter weights[J].Frontiers in Nutrition,2022,9:899871. [2] ZHOU X H,ZHANG Y M,WU X,et al.Effects of dietary serine supplementation on intestinal integrity,inflammation and oxidative status in early-weaned piglets[J].Cellular Physiology and Biochemistry,2018,48(3):993-1002. [3] HE L Q,LONG J,ZHOU X H,et al.Serine is required for the maintenance of redox balance and proliferation in the intestine under oxidative stress[J].The FASEB Journal,2020,34(3):4702-4717. [4] HE Y W,LIU Y H,GUAN P,et al.Serine administration improves selenium status,oxidative stress,and mitochondrial function in longissimus dorsi muscle of piglets with intrauterine growth retardation[J].Biological Trace Element Research,2023,201(4):1740-1747. [5] OGBUAGU N E,AYO J O.Effects of L-serine administration on meat quality,characteristics and mineral content of tibia bone in heat-stressed broiler[J].Veterinary Integrative Sciences,2022,21(1):131-144. [6] WANG W W,DAI Z L,WU Z L,et al.Glycine is a nutritionally essential amino acid for maximal growth of milk-fed young pigs[J].Amino Acids,2014,46(8):2037-2045. [7] YUN J,FAN X X,ZHANG Y C,et al.Glycine regulates mucosal immunity and the intestinal microbial composition in weaned piglets[J].Amino Acids,2022,54(3):385-398. [8] HOU Y Q,WU G Y.L-glutamate nutrition and metabolism in swine[J].Amino Acids,2018,50(11):1497-1510. [9] KANG D R,BELAL S A,CHO E S R,et al.Meat quality and chemical assessment of porcine longissimus dorsi within different muscle pH[J].Animal Production Science,2019,59(6):1155-1160. [10] DUAN Y H,ZHENG C B,ZHENG J,et al.Profiles of muscular amino acids,fatty acids,and metabolites in Shaziling pigs of different ages and relation to meat quality[J].Science China.Life Sciences,2023,66(6):1323-1339. [11] 程天德,钟南.粤北山区散养模式下麻鸡的主要呈味氨基酸研究——以清远麻鸡为例[J].湖北农业科学,2020,59(2):125-127. CHENG T D,ZHONG N.Study on the main flavor amino acids of the hemp chickens in the free-range breeding mode in northern mountains of Guangdong:Take Qingyuan Pai chicken as an example[J].Hubei Agricultural Sciences,2020,59(2):125-127.(in Chinese) [12] 周辉,关鹏,王晨昱,等.丝氨酸对宫内发育迟缓哺乳仔猪生长性能、肠道形态结构和免疫相关指标的影响[J].畜牧兽医学报,2023,54(10):4220-4232. ZHOU H,GUAN P,WANG C Y,et al.Effects of serine on growth performance,intestinal morphology and immune related indexes of suckling piglets with intrauterine growth retardation[J].Acta Veterinaria et Zootechnica Sinica,2023,54(10):4220-4232.(in Chinese) [13] GUO Y T,HE F,DENG Z Y,et al.Dietary serine supplementation improves growth performance,intramuscular fat content,and composition of gut microbes and metabolites in growing-finishing pigs[J].Agriculture,2024,14(3):349. [14] 周腊枚,周锡红.丝氨酸的生理功能及其在猪生产中的应用研究进展[J].中国畜牧杂志,2022,58(1):71-76. ZHOU L M,ZHOU X H.Research progress on physiological functions of serine and its application in pig production[J].Chinese Journal of Animal Science,2022,58(1):71-76.(in Chinese) [15] LONG J,LIU Y H,ZHOU X H,et al.Dietary serine supplementation regulates selenoprotein transcription and selenoenzyme activity in pigs[J].Biological Trace Element Research,2021,199(1):148-153. [16] 曾思静,刘永辉,龙静,等.围产期母猪饲粮补充丝氨酸对泌乳母猪和哺乳仔猪血清生化指标和抗氧化功能的影响[J].动物营养学报,2021,33(4):1976-1985. ZENG S J,LIU Y H,LONG J,et al.Effects of serine supplementation in diets for perinatal sows on serum biochemical indices and antioxidant function of lactating sows and suckling piglets[J].Chinese Journal of Animal Nutrition,2021,33(4):1976-1985.(in Chinese) [17] HE L Q,ZHANG H W,ZHOU X H.Weanling offspring of dams maintained on serine-deficient diet are vulnerable to oxidative stress[J].Oxidative Medicine and Cellular Longevity,2018,2018:8026496. [18] 刘永辉,李响,周锡红,等.低蛋白质饲粮中丝氨酸和甘氨酸比例对育肥猪背最长肌氧化应激状态的影响[J].动物营养学报,2020,32(7):3109-3117. LIU Y H,LI X,ZHOU X H,et al.Effects of serine to glycine ratio in low protein diet on oxidative stress status in longissimus dorsi of finishing pigs[J].Chinese Journal of Animal Nutrition,2020,32(7):3109-3117.(in Chinese) [19] ZHOU X H,LIU Y H,ZHANG L Y,et al.Serine-to-glycine ratios in low-protein diets regulate intramuscular fat by affecting lipid metabolism and myofiber type transition in the skeletal muscle of growing-finishing pigs[J].Animal Nutrition,2021,7(2):384-392. [20] AMBERG R,MIZUTANI T,WU X Q,et al.Selenocysteine synthesis in mammalia:An identity switch from tRNA(Ser) to tRNA(Sec)[J].Journal of Molecular Biology,1996,263(1):8-19. [21] JIANG S W,QUAN W,LUO J,et al.Low-protein diets supplemented with glycine improves pig growth performance and meat quality:An untargeted metabolomic analysis[J]. Frontiers in Veterinary Science,2023,10:1170573. [22] ZHONG Y Z,YAN Z M,SONG B,et al.Dietary supplementation with betaine or glycine improves the carcass trait,meat quality and lipid metabolism of finishing mini-pigs[J].Animal Nutrition,2021,7(2):376-383. [23] WU W S,WANG Y L,ZOU J J,et al.Bifidobacterium adolescentis protects against necrotizing enterocolitis and upregulates TOLLIP and SIGIRR in premature neonatal rats[J].BMC Pediatrics,2017,17(1):1. [24] XU X,WANG X Y,WU H T,et al.Glycine relieves intestinal injury by maintaining mTOR signaling and suppressing AMPK,TLR4,and NOD signaling in weaned piglets after lipopolysaccharide challenge[J].International Journal of Molecular Sciences,2018,19(7):1980. [25] LIU G M,GU K,LIU X L,et al.Dietary glutamate enhances intestinal immunity by modulating microbiota and Th17/Treg balance-related immune signaling in piglets after lipopolysaccharide challenge[J].Food Research International,2023,166(4):112597. [26] 胡诚军,张婷,李华伟,等.饲粮添加亮氨酸和谷氨酸对肥育猪生长性能、胴体性状和肉品质的影响[J].动物营养学报,2017,2(29):590-596. HU C J,ZHANG T,LI H W,et al.Effects of dietary leucine and glutamic acid supplementation on growth performance,carcass traits and meat quality of finishing pigs[J].Chinese Journal of Animal Nutrition,2017,2(29):590-596.(in Chinese) [27] 方桂友,郭庆,董志岩.谷氨酸对断乳仔猪生长性能、血浆抗氧化和免疫指标的影响[J].福建畜牧兽医,2023,45(3):7-11. FANG G Y,GUO Q,DONG Z Y.Effects of glutamate on the growth performance,plasma antioxidant and immune indicators in weaning piglets[J].Fujian Animal Husbandry Veterinarian,2023,45(3):7-11.(in Chinese) [28] 方桂友,郭庆,刘景,等.低蛋白质氨基酸平衡饲粮添加谷氨酸和精氨酸对断奶仔猪生长性能和血液指标的影响[J].福建农业学报,2022,37(11):1407-1414. FANG G Y,GUO Q,LIU J,et al.Effects of amino acid-balanced low-protein diet supplemented with glutamate and arginine on growth and serum indicators of weaned piglets[J].Fujian Journal of Agricultural Sciences,2022,37(11):1407-1414.(in Chinese) [29] ZIMMERMAN D R.Glutamic acid and tryptophan additions to a low-protein pig starter[J].Journal of Animal Science,1975,40(5):871-874. [30] 许庆庆.低蛋白日粮平衡谷氨酸对育肥猪蛋白质利用及生长性能的影响研究[D].重庆:西南大学,2017. XU Q Q.Study on the effects of balancing low-protein diets with glutamate on the utilization of protein and growth performance of finishing pigs[D].Chongqing:Southwest University,2017.(in Chinese) [31] UPADHAYA S D,LEE S S,KIM Y H,et al.Effects of supplementation of graded level of glutamic acid to crude protein reduced diets on the performance of growing pigs[J].Journal of Animal Physiology and Animal Nutrition,2022,106(4):825-831. [32] YIN J,LIU M F,REN W K,et al.Effects of dietary supplementation with glutamate and aspartate on diquat-induced oxidative stress in piglets[J].PLoS One,2015,10(4):e0122893. [33] 胡诚军.饲粮添加精氨酸和谷氨酸对肥育猪肉品质的影响及机制研究[D].广州:华南农业大学,2017. HU C J.Effects of dietary supplementation with arginine and glutamate on meat quality and its mechanism in growing-finishing pigs[D].Guangzhou:South China Agricultural University,2017.(in Chinese) [34] HU C J,JIANG Q Y,ZHANG T,et al.Dietary supplementation with arginine and glutamic acid enhances key lipogenic gene expression in growing pigs[J].Journal of Animal Science,2017,95(12):5507-5515. [35] 杨翠,罗鲜青,黄丽霞,等.日粮中添加富利宝和谷氨酸对猪肥育与屠宰性能及肉品质的影响[J].家畜生态学报,2016,37(2):28-33. YANG C,LUO X Q,HUANG L X,et al.Effect of diet with Fulibao and glutamic acid on finishing and slaughter performances and meat quality of swine[J].Journal of Domestic Animal Ecology,2016,37(2):28-33.(in Chinese) [36] LIU T,PENG J,XIONG Y Z,et al.Effects of dietary glutamine and glutamate supplementation on small intestinal structure,active absorption and DNA,RNA concentrations in skeletal muscle tissue of weaned piglets during d 28 to 42 of age[J].Asian-Australasian Journal of Animal Sciences,2002,15(2):238-242. [37] WU X,ZHANG Y,LIU Z,et al.Effects of oral supplementation with glutamate or combination of glutamate and N-carbamylglutamate on intestinal mucosa morphology and epithelium cell proliferation in weanling piglets[J].Journal of Animal Science,2012,90(4):337-339. [38] 秦颖超,宋志文,朱敏,等.谷氨酸通过保护回肠结构完整性增强猪回肠屏障功能[J].动物营养学报,2020,32(5):2101-2107. QIN Y C,SONG Z W,ZHU M,et al.Glutamate enhances porcine ileal barrier function via protecting ileal structural integrality[J].Chinese Journal of Animal Nutrition,2020,32(5):2101-2107.(in Chinese) [39] LIN M,ZHANG B L,YU C N,et al.L-glutamate supplementation improves small intestinal architecture and enhances the expressions of jejunal mucosa amino acid receptors and transporters in weaning piglets[J].PLoS One,2014,9(11):e111950. [40] JIAO N,WU Z L,JI Y,et al.L-glutamate enhances barrier and antioxidative functions in intestinal porcine epithelial cells[J].The Journal of Nutrition,2015,145(10):2258-2264. [41] QIN Q,XU X,WANG X Y,et al.Glutamate alleviates intestinal injury,maintains mTOR and suppresses TLR4 and NOD signaling pathways in weanling pigs challenged with lipopolysaccharide[J].Scientific Reports,2018,8(1):15124. [42] 张明伟.不同水平天冬氨酸对断奶仔猪生长性能的影响[J].中国动物保健,2022,24(9):74-75. ZHANG M W.Effects of different levels of aspartic acid on growth performance of weaned piglets[J].China Animal Health,2022,24(9):74-75.(in Chinese) [43] 王晨昱,刘永辉,李响,等.D-天冬氨酸对断奶仔猪生长性能、血清生化指标和营养物质表观消化率的影响[J].动物营养学报,2021,33(6):3154-3164. WANG C Y,LIU Y H,LI X,et al.Effects of D-aspartate on growth performance,serum biochemical indices and nutrient apparent digestibilities in weaned piglets[J].Chinese Journal of Animal Nutrition,2021,33(6):3154-3164.(in Chinese) [44] 关鹏,王晨昱,胡鲜,等.低蛋白日粮补充天冬氨酸对断奶至育肥阶段猪生长性能及肉品质性状的影响[J].畜牧兽医学报,2022,53(10):3500-3510. GUAN P,WANG C Y,HU X,et al.Effects of aspartic acid supplementation in low-protein diets on growth performance and meat quality traits of pigs from weaning to fattening[J].Acta Veterinaria et Zootechnica Sinica,2022,53(10):3500-3510.(in Chinese) [45] WU G Y,WU Z L,DAI Z L,et al.Dietary requirements of "nutritionally non-essential amino acids" by animals and humans[J].Amino Acids,2013,44(4):1107-1113. [46] CHEN L L,ZHONG Y,OUYANG X Q,et al.Effects of β-alanine on intestinal development and immune performance of weaned piglets[J].Animal Nutrition,2023,12(1):398-408. [47] WANG F,YIN Y X,WANG Q Y,et al.Effects of dietary beta-alanine supplementation on growth performance,meat quality,carnosine content,amino acid composition and muscular antioxidant capacity in Chinese indigenous Ningxiang pig[J].Journal of Animal Physiology and Animal Nutrition,2022,107(3):878-886. [48] OGBUAGU N E,AYO J O,ALUWONG T,et al.L-serine modulates activities of antioxidant enzymes and behavioral responses in broiler chickens subjected to feed restriction during the hot-dry season[J].Journal of Veterinary Behavior,2023,60(2):1-9. [49] WANG F G,ZHOU H B,DENG L G,et al.Serine deficiency exacerbates inflammation and oxidative stress via microbiota-gut-brain axis in D-galactose-induced aging mice[J].Mediators of Inflammation,2020,2020(1):5821428. [50] ZHOU J M,QIU K,WANG J,et al.Effect of dietary serine supplementation on performance,egg quality,serum indices,and ileal mucosal immunity in laying hens fed a low crude protein diet[J].Poultry Science,2021,100(12):101465. [51] DEAN D W,BIDNER T D,SOUTHERN L L.Glycine supplementation to low protein,amino acid-supplemented diets supports optimal performance of broiler chicks[J].Poultry Science,2006,85(2):288-296. [52] WON S Y,HAN G P,KWON C H,et al.Effect of individual or combination of dietary betaine and glycine on productive performance,stress response,liver health,and intestinal barrier function in broiler chickens raised under heat stress conditions[J].Poultry Science,2023,102(7):102771. [53] 冯倩倩.低蛋白饲粮中甘氨酸和胱氨酸水平及其组合效应促进肉仔鸡生长的机理[D].北京:中国农业科学院,2021. FENG Q Q.Dietary level of glycine and cystine and their combinative effects on stimulation of growth of broiler chickens fed low protein diet[D].Beijing:Chinese Academy of Agricultural Sciences,2021.(in Chinese) [54] HOFMANN P,SIEGERT W,KENÉZ Á,et al.Very low crude protein and varying glycine concentrations in the diet affect growth performance,characteristics of nitrogen excretion,and the blood metabolome of broiler chickens[J].The Journal of Nutrition,2019,149(7):1122-1132. [55] ALLEN P J.Creatine metabolism and psychiatric disorders:Does creatine supplementation have therapeutic value?[J].Neuroscience and Biobehavioral Reviews,2012,36(5):1442-1462. [56] NGO A,COON C N,BEECHER G R.Dietary glycine requirements for growth and cellular development in chicks[J].The Journal of Nutrition,1977,107(10):1800-1808. [57] CHRYSTAL P V,MOSS A F,YIN D,et al.Glycine equivalent and threonine inclusions in reduced-crude protein,maize-based diets impact on growth performance,fat deposition,starch-protein digestive dynamics and amino acid metabolism in broiler chickens[J].Animal Feed Science and Technology,2020,261(3):114387. [58] MASLAMI V,NOERSIDIQ A,FAHRULLAH F,et al.Effect of glutamate supplementation in broiler chicken feed to the quality of carcass[J].Journal Biologi Tropis,2023,23(2):398-405. [59] MASLAMI V,JAMSARI M.Effect of glutamate supplementation as a feed additive on performance of broiler chickens[J].Journal of World’s Poultry Research,2019,9(3):154-159. [60] EBADIASL G.Effects of supplemental glutamine and glutamate on growth performance,gastrointestinal development,jejunum morphology and Clostridium perfringens count in caecum of broilers[D].Uppsala:Swedish University of Agricultural Science,2011. [61] MARUYAMA K,SUNDE M L,HARPER A E.Effect of D-alanine and D-aspartic acid on the chick[J].The Journal of Nutrition,1972,102(11):1441-1451. [62] DO P H,TRAN P V,BAHRY M A,et al.Oral administration of a medium containing both D-aspartate-producing live bacteria and D-aspartate reduces rectal temperature in chicks[J].British Poultry Science,2017,58(5):569-577. [63] ERWAN E,TOMONAGA S,YOSHIDA J,et al.Central administration of L- and D-aspartate attenuates stress behaviors by social isolation and CRF in neonatal chicks[J].Amino Acids,2012,43(5):1969-1976. [64] QI B,WANG J,MA Y B,et al.Effect of dietary beta-alanine supplementation on growth performance,meat quality,carnosine content,and gene expression of carnosine-related enzymes in broilers[J].Poultry Science,2018,97(4):1220-1228. [65] PARK S W,KIM C H,NAMGUNG N,et al.Effects of dietary supplementation of histidine,β-alanine,magnesium oxide,and blood meal on carnosine and anserine concentrations of broiler breast meat[J].The Journal of Poultry Science,2013,50(3):251-256. [66] TOMONAGA S,KANEKO K,KAJI Y,et al.Dietary β-alanine enhances brain,but not muscle,carnosine and anserine concentrations in broilers[J].Animal Science Journal,2006,77(1):79-86. [67] 齐博.β-丙氨酸对肉仔鸡生产性能、肌肉品质和肌源活性肽的影响[D].北京:中国农业科学院,2017. QI B.Effect of β-alanine on growth performance,meat quality and muscle-derived active peptide[D].Beijing:Chinese Academy of Agricultural Sciences,2017.(in Chinese) [68] QI B,WANG J,HU M,et al.Influences of beta-alanine and L-histidine supplementation on growth performance,meat quality,carnosine content,and mrna expression of carnosine-related enzymes in broilers[J].Animals (Basel),2021,11(8):2265. [69] KRAILK G,SAK-BOSNAR M,GRCEVIC M,et al.Effect of amino acids on growth performance,carcass characteristics,meat quality,and carnosine concentration in broiler chickens[J].The Journal of Poultry Science,2018,55(4):239-248. [70] PAUL K,WANG S B,CHEN S F,et al.Effects of central administration of glutamine and alanine on feed intake and hypothalamic expression of orexigenic and anorexigenic neuropetides in broiler chicks[J].Journal of Integrative Agriculture,2012,11(7):1173-1180. |