畜禽肌肉肌苷酸研究进展

doi:10.16431/j.cnki.1671-7236.2025.02.019

摘要/Abstract

摘要： 肌苷酸(inosine monophosphate，IMP)作为嘌呤代谢的中间产物，参与细胞内的能量代谢与信号传导。同时，肌苷酸是畜禽肉中的关键风味前体物质，与氨基酸、糖类等物质发生复杂相互作用产生香气化合物，显著提升畜禽肉鲜味和香味。肌苷酸含量是肉质风味的重要评价指标，也是影响畜禽肉产品经济价值的重要因素。因此，肌苷酸对肉品质的影响、肌苷酸沉积的遗传调控机制备受关注。肌苷酸的合成与代谢受到众多基因的网络式调控。随着现代分子生物学技术的发展，研究人员深入解析肌苷酸的合成与代谢途径，揭示了若干关键酶和调控基因。目前，多组学技术已广泛应用于畜禽重要经济性状的遗传机制解析，畜禽肌肉肌苷酸沉积的调控机制有望进一步突破。文章主要对畜禽肌肉肌苷酸的研究进展进行综述，介绍了肌苷酸的结构和检测方法，简述了肌苷酸对肉品质的影响，回顾了肌苷酸合成与代谢作用机制，分析了影响肌苷酸合成代谢的主要因素等，为深入研究肌苷酸的合成与代谢机制、畜禽肉质风味调控机制和畜禽遗传育种改良提供理论参考。

关键词: 肌苷酸; 畜禽; 肉品质; 作用机制

Abstract: Inosine monophosphate (IMP)，as an intermediate product of purine metabolism，is involved in intracellular energy metabolism and signal transduction.Meanwhile，IMP is a key flavor precursor in livestock and poultry muscle.It has complex interactions with amino acids,sugars and other substances to produce aroma compounds，which significantly improves the umami and aroma of livestock and poultry muscle.IMP content is an important evaluation index for meat flavor and a significant factor affecting the economic value of livestock and poultry muscle products.Therefore，the impact of IMP on meat quality and the genetic regulatory mechanisms of IMP deposition have garnered significant attention.The synthesis and metabolism of IMP are regulated by a network of numerous genes.With the development of modern molecular biology techniques，researchers have delved into the synthesis and metabolic pathways of IMP，revealing several key enzymes and regulatory genes.Currently，multi-omics technologies have been widely applied to elucidate the genetic mechanism underlying important economic traits in livestock and poultry，and further breakthroughs are expected in understanding the regulatory mechanism of IMP deposition in livestock and poultry muscle.This article provides an overview of the research progress on IMP in livestock and poultry muscle，introduces the structure and detection methods of IMP，outlines its impact on meat quality，reviews the mechanism of IMP synthesis and metabolism，and analyzes the main factors affecting IMP synthesis and metabolism.This review serves as a theoretical reference for further research on the synthesis and metabolism mechanism of IMP，the regulation mechanism of meat flavor in livestock and poultry，and the genetic improvement of livestock and poultry breeding.

Key words: inosine monophosphate; livestock and poultry; meat quality; mechanism of action

中图分类号:

S813.3

张瑶, 朱礼阳, 杨莹, 侯静严, 韩涛泽, 王凯龙, 徐垭烯, 盛熙晖. 畜禽肌肉肌苷酸研究进展[J]. 中国畜牧兽医, 2025, 52(2): 686-697.

ZHANG Yao, ZHU Liyang, YANG Ying, HOU Jingyan, HAN Taoze, WANG Kailong, XU Yaxi, SHENG Xihui. Research Progress on Inosine Monophosphate in Livestock and Poultry Muscle[J]. China Animal Husbandry and Veterinary Medicine, 2025, 52(2): 686-697.

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