›› 2016, Vol. 43 ›› Issue (11): 2982-2988.doi: 10.16431/j.cnki.1671-7236.2016.11.026

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Association Analysis on MAP3K5 Gene Polymorphism Site with Growth and Feed Efficiency Related Traits in Duroc Pigs

PU Lei1,2, YUE Jing-wei1, ZHANG Jin-shan1, LIU Xin1, WANG Li-gang1, YAN Hua1, HOU Xin-hua1, GAO Hong-mei1, ZHANG Tian1, ZHANG Yue-bo1, WU Qun-qing1,3, ZHANG Long-chao1, WANG Li-xian1   

  1. 1. Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China;
    2. College of Animal Science and Veterinary Medicine, Tianjin Agricultural University, Tianjin 300384, China;
    3. College of Animal Science Technology, Hunan Agricultural University, Changsha 410128, China
  • Received:2016-05-16 Online:2016-11-20 Published:2016-11-18

Abstract:

This study was aimed to analyze the association of four SNPs of MAP3K5 gene with growth and feed efficiency related traits in Duroc populations. Four SNPs(Ssc1:30769583 A>C;Ssc1:30781169 A>G;Ssc1:30940839 A>G;Ssc1:30962276 G>A)of MAP3K5 gene in Duroc populations were obtained by porcine SNP60 BeadChip(Illumina). The genotype frequency and allele frequency of four SNPs of MAP3K5 gene were analyzed,the result showed that four SNPs were the low-moderate mutation SNPs.The polymorphism of MAP3K5 gene and its association with feed efficiency related traits in Duroc population were analyzed. The results indicated that CC genotype individuals in Ssc1:30769583 A>C had significant lower RFI(133.08 g/d)than AA genotype individuals(P<0.05);GG genotype individuals in Ssc1:30781169 A>G had significant lower RFI(116.18 g/d)and ADFI(0.23 kg/d)than AG genotype individuals(P<0.05);GG genotype individuals in Ssc1:30940839 A>G had significant lower FCR(0.10%)than AG genotype individuals(P<0.05);AA genotype individual in Ssc1:30962276 G>A had significant lower ADG(0.04 kg/d)than GG genotype individuals(P<0.05). All in all,the results suggested that four SNPs polymorphisms of MAP3K5 gene had the significant impact on RFI, ADFI, FCR and ADG traits in Duroc pigs.

Key words: MAP3K5 gene; Duroc pig; SNP; RFI; feed utilization efficiency

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