›› 2009, Vol. 36 ›› Issue (5): 49-52.

• 生理生化 • 上一篇    下一篇

混饮低剂量ChIFN-α对健康肉鸡免疫功能及生产性能的影响

陶胜利, 邱银生, 张艳萍, 朱江江, 向志威, 朱惠玲   

  1. (武汉工业学院饲料科学系 动物营养与饲料科学湖北省重点实验室, 武汉 430023)
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2009-05-20 发布日期:2009-05-20
  • 通讯作者: 邱银生

Effects of Drinking Administration of Low-dose ChIFN-α on Immune Function and Growth Performance of Health Broilers

TAO Sheng-li,QIU Yin-sheng,ZHANG Yan-ping,ZHU Jiang-jiang,XIANG Zhi-wei,ZHU Hiu-ling   

  1. (Hubei Key Laboratory of Animal Nutrition and Feed Science,Department of Feed Science,Wuha n Polytechnic University,Wuhan 430023,China)
  • Received:1900-01-01 Revised:1900-01-01 Online:2009-05-20 Published:2009-05-20
  • Contact: QIU Yin-sheng

摘要: 试验选取50只雏肉鸡饲养至14日龄,随机分为5组,每组10只, 14~42日龄期间试验Ⅱ、Ⅲ、Ⅳ组每日分别混饮0.1、1.0、10 U/mL剂量ChIFN-α(鸡干扰素-α),Ⅰ组设为空白组,混饮自来水。Ⅴ组设为阳性对照,混饮50 mg/L盐酸左旋咪唑,研究混饮ChIFN-α后对肉鸡免疫功能及生产性能的影响。结果显示,混饮ChIFN-α后可提高肉鸡外周血白细胞总数、淋巴细胞百分比和嗜碱性粒细胞百分比,降低嗜中性粒细胞百分比和单核细胞百分比;提高肉鸡脾脏指数及血清总蛋白(TP)、血清白蛋白(ALB)、血清球蛋白(GLO)的浓度及ALB/GLO比值;不影响肉鸡的生长发育。因此,混饮低剂量的ChIFN-α可提高肉鸡的免疫功能,对健康肉鸡的生长无显著的影响。

关键词: 肉鸡; 鸡干扰素-α; 混饮; 低剂量; 免疫功能; 生长性能

Abstract: In the experiments 50 broiles reared to 14 d are selected ,randomly is divided into 5 groups of 10 broilers.During 14 to 42 d the test group Ⅱ, Ⅲ, Ⅳ are administrated continuously ChIFN-α in drinking water followed by 0.1,1.0 and 10 U/mL respectively. Ⅰ group as the control group is only given water.Ⅴ group as positive control is administrated 50 mg/L levamisole hydrochloride. The experiments is designed to study the effects of ChIFN-α on immune function and growth performance after the broilers are administrated in drinking water. The results show ChIFN-α can increase the total number of leukocytes in peripheral blood of broilers,the percentage of lymphocytes, the percentage of basophils,reduce the percentage of neutrophils and monocytes, raise chickens spleen index,as well as the concentration of serum total protein (TP), serum albumin (ALB),serum globulin (GLO) and ALB/GLO ratio; and can not impact on the broiler growth and development obviously after drinking administration. As a result, administration of low-dose ChIFN-α in broilers drinking water can enhance the immune function of broilers, and can not impact significantly on the growth the healthy broilers.

Key words: broilers; ChIFN-α; drinking administration; low-dose; immune function; growth performance

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