芪蓝复方对围产期母猪免疫、繁殖及排便功能的影响

doi:10.16431/j.cnki.1671-7236.2025.05.037

摘要/Abstract

摘要： 【目的】揭示芪蓝复方对围产期母猪免疫、繁殖及排便功能的影响，为提高围产期母猪健康水平提供参考。【方法】选取25头二元母猪(30～40 胎龄)，均分为空白组(N)，0.1%、0.2%和0.4%芪蓝复方组(L、M和H)及阳性对照组(A)，每组5个重复，每个重复1头母猪。空白组母猪饲喂基础饲粮，芪蓝复方组分别在基础饲粮中添加0.1%、0.2%和0.4%芪蓝复方，阳性对照组在基础饲粮中添加50 mg/kg爱乐新。试验自妊娠91 d开始，至断奶(产后21 d)结束，妊娠91 d、产后4和21 d采血，检测芪蓝复方对母猪血清中总抗氧化能力(T-AOC)、谷胱甘肽过氧化物酶(GSH-Px)、超氧化物歧化酶(SOD)活性或和丙二醛(MDA)、免疫球蛋白(IgG、IgM和IgA)、炎症因子(白细胞介素-6(IL-6)和IL-1β)、胃肠激素(血清P物质(SP)、胃动素(MTL)和血管活性肠肽(VIP)含量)及猪繁殖与呼吸综合征病毒(PRRSV)抗体水平的影响，统计繁殖功能指标和便秘率，并于产后21 d收集试验猪粪便，检测芪蓝复方对粪便短链脂肪酸(SCFAs)的影响。【结果】产后4和21 d,与N组相比，芪蓝复方组母猪血清中T-AOC、GSH-Px和SOD活性显著升高(P＜0.05)，MDA含量显著降低(P＜0.05)；免疫球蛋白IgG、IgM和IgA含量显著提高(P＜0.05)，IL-6和IL-1β含量显著降低(P＜0.05)，其中H组效果最显著；PRRSV抗体S/P值显著降低(P＜0.05)；VIP含量显著降低(P＜0.05)，SP和MTL含量显著上升(P＜0.05)。与N组相比，芪蓝复方组死胎率和弱仔率显著降低(P＜0.05)，初生窝重和断奶窝重显著提升(P＜0.05)，母猪便秘率显著降低(P＜0.05)；芪蓝复方组母猪粪便SCFAs含量显著上升(P＜0.05)。【结论】芪蓝复方对围产期母猪免疫、繁殖及排便功能具有显著促进作用，饲粮中添加0.4%芪蓝复方效果最佳，可用于围产期母猪保健。

关键词: 芪蓝复方; 围产期母猪; 免疫功能; 繁殖功能; 排便功能

Abstract: 【Objective】 This experiment was conducted to reveal the effects of Qilan compound on immunity function,reproduction performance and defecation function of perinatal sows,and provide a reference for improving the health of perinatal sows.【Method】 Twenty-five binary sows (30-40 gestational age) were selected and divided into blank group (N),0.1%,0.2% and 0.4% Qilan compound groups (L,M and H) and positive control group (A),5 replicates per group and 1 sow per replicate.The pigs in Qilan compound groups were supplemented with 0.1%,0.2% and 0.4% Qilan compound in the basal diet,respectively,and pigs in positive control group were supplemented with 50 mg/kg Elaxin in the basal diet.The test started on day 91 of gestation and ended at weaning (21 days postpartum).Blood was collected at 91 days of gestation,4 and 21 days postpartum to measure the serum antioxidant function (T-AOC,GSH-Px,SOD and MDA),immunoglobulins (IgG,IgM and IgA),inflammation factors (IL-6 and IL-1β) and gastrointestinal hormones (SP,MTL and VIP) contents and PRRSV antibody levels.Reproductive function indicators and constipation rate were counted,and the feces of the test pigs were collected at 21 days after parturition to detect the effect of Qilan compound on fecal short-chain fatty acids.【Result】 On postnatal days 4 and 21,compared with group N,T-AOC,GSH-Px and SOD activities in serum of sows in Qilan compound groups were significantly increased (P＜0.05),and MDA content were significantly decreased (P＜0.05);The contents of immunoglobulin IgG,IgM and IgA were significantly increased (P＜0.05),and the contents of IL-6 and IL-1β were significantly decreased (P＜0.05),and H group had the most significant effect;S/P value of PRRSV antibody was significantly decreased (P＜0.05);The content of VIP was decreased significantly (P＜0.05),and the contents of SP and MTL were increased significantly (P＜0.05).Compared with group N,the rate of stillbirth and weak piglets were significantly decreased in the Qilan compound groups (P＜0.05),litter weight at birth and weight of weaning litter were significantly increased (P＜0.05);The constipation rate in Qilan compound group were significantly decreased (P＜0.05);The content of SCFAs in feces of sows in Qilan compound group were significantly increased (P＜0.05).【Conclusion】 Qilan compound had a significant effect on the immunity function,reproduction performance and defecation function of perinatal sows,the effect of 0.4% Qilan compound in diet was the best,and could be used for perinatal sow health care.

Key words: Qilan compound; perinatal sows; immunity function; reproduction performance; defecation function

中图分类号:

S853.7

臧欣怡, 张偌益, 陈泽晗, 范舒钰, 李健. 芪蓝复方对围产期母猪免疫、繁殖及排便功能的影响[J]. 中国畜牧兽医, 2025, 52(5): 2341-2352.

ZANG Xinyi, ZHANG Ruoyi, CHEN Zehan, FAN Shuyu, LI Jian. Effects of Qilan Compound on Immune Function,Reproductive Performance and Defecation Function of Perinatal Sows[J]. China Animal Husbandry and Veterinary Medicine, 2025, 52(5): 2341-2352.

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