›› 2012, Vol. 39 ›› Issue (10): 181-184.

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The Polymorphism of IGF-Ⅰ Gene and its Relationship with some Growth Traits in Saba Pig

DING Yan1, LU Shao-xiong2, LIAN Lin-sheng2   

  1. 1. Bureau of Stock Raising and Veterinary Medicine of Zhanyi County, Zhanyi 655331, China;
    2. Faculty of Animal Science and Technology, Yunnan Agricultural University, Kunming 650201, China
  • Received:2012-04-01 Online:2012-10-20 Published:2012-10-19

Abstract: The expression products of insulin-like growth factor-Ⅰ (IGF-Ⅰ) gene play an important role in muscle growth of pigs. In this research, IGF-Ⅰ gene was chosen as candidate genes for growth traits of Saba pigs. The HhaⅠ polymorphism of the gene was investigated by using PCR-RFLP technology, and the relationship between the polymorphism and 12 growth traits was analyzed. The results showed that there was a higher degree of polymorphisms on IGF-Ⅰ gene in the population. AA, AB, BB genotypes of IGF-Ⅰ gene were detected in Saba pigs, which frequency were 0.3473, 0.5149, 0.1378, respectively. The frequency of A and B were 0.6048 and 0.3952, respectively. The gene loci was in Hardy-Weinberg equilibration. The genetic variation of IGF-Ⅰ gene of Saba pigs had significant influence on growth traits (P<0.05 or P<0.01). The favorable genotype of the body weight and the daily gains at different growth stages was AB genotype,and the favorable genotype of the body size traits at 6 months was BB genotype except partial traits was AB genotype. Combining with the previous results, it could be primarily deduced that IGF-Ⅰ gene was probably a major gene or a QTL linked gene that associated with growth traits in pigs.

Key words: Saba pig; IGF-Ⅰ gene; polymorphism; growth traits

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