中药复方灌注剂对奶牛乳房炎的防治效果及免疫增强作用

›› 2011, Vol. 38 ›› Issue (7): 219-224.

中药复方灌注剂对奶牛乳房炎的防治效果及免疫增强作用

孟庆娟¹, 李志明², 冯士彬¹, 王希春¹, 韩春杨¹, 邹松阳², 刘琦山², 吴金节¹

1. 安徽农业大学动物科技学院,安徽合肥 230036;2. 安徽白帝乳业有限公司,安徽合肥 230031

收稿日期:2010-12-16 修回日期:1900-01-01 出版日期:2011-07-20 发布日期:2011-07-20
通讯作者: 吴金节

Prevention and Cure Effect and Immunological Enhancement of the Complex Perfusion Fluid of the Traditional Chinese Medicine to Mastitis of Dairy Cows

MENG Qing-juan¹, LI Zhi-ming², FENG Shi-bin¹, WANG Xi-chun¹, HAN Chun-yang¹, ZOU Song-yang², LIU Qi-shan², WU Jin-jie¹

1. College of Animal Science and Technology,Anhui Agricultural University,Hefei 230036,China;2. Anhui Baidi Milk Limited Company,Hefei 230031,China

Received:2010-12-16 Revised:1900-01-01 Online:2011-07-20 Published:2011-07-20

摘要/Abstract

摘要： 选取临床型、隐性型和健康型荷斯坦奶牛共80头,用于中药复方灌注剂对奶牛乳房炎的防治及免疫试验,对治疗前后乳中体细胞数(SCC)、乳清中白蛋白(SA)、乳酸脱氢酶(LDH)、丙氨酸氨基转移酶(ALT)、天门冬氨酸氨基转移酶(AST)、淋巴细胞刺激指数(SI)、嗜中性粒细胞吞噬率和使用前后干奶期乳房炎的发病率进行了研究。结果表明,中药复方灌注剂和抗生素对隐性乳房炎的治愈率分别为94.44%和88.24%,有效率均为100%;对临床型乳房炎的治愈率分别为86.67%和76.92%,有效率为93.33%和84.62%;对干奶期乳房炎的预防效果分别为88.89%和94.12%,而生理盐水对照组发病率高达45.45%。中药复方灌注剂可以极显著降低患病奶牛乳中SCC、SA、LDH、ALT、AST水平(P＜0.01),提高SI和嗜中性粒细胞吞噬率(P＜0.01)。试验证实了中药复方灌注剂对奶牛乳房炎有较好的防治效果,能够修复奶牛受损的乳腺上皮细胞,降低受损细胞产生的酶含量和血乳的渗透性,提高患病奶牛机体的免疫机能。

关键词: 中药; 灌注剂; 乳房炎; 体细胞数; 淋巴细胞

Abstract: 80 dairy cows were selected in order to observe the prevention and cure effect and immunological enhancement of the traditional Chinese medicine complex perfusion fluid to mastitis. The SCC,SA,ALT,AST,LDH,SI,the rate of neutrophil phagocytosis of dairy cows with mastitis during cure were measured,and the incidence of mastitis was observed in the dry period. The results showed that the cure rate of sub-clinical mastitis by traditional Chinese medicine complex perfusion fluid and antibiotics were respectively 94.44% and 88.24%,and the effective rate were 100%. The cure rate of clinical mastitis in dairy cows were respectively 86.67% and 84.62%,and the effective rate were 93.33% and 91.67%. The preventive effects of mastitis in dry period were 88.89% and 94.12%,while the incidence rate in the control group was 42.86%. The levels of SCC,SA,ALT,AST,LDH were significantly decreased by the traditional Chinese medicine complex perfusion fluid,and the levels of SI and the rate of neutrophil phagocytosis were significantly increased (P<0.01). The experiment showed that the traditional Chinese medicine complex perfusion fluid had a better treat effect on mastitis,which can repair damaged mammary gland epithelial cells and reduce the permeability of the blood-milk and the activity of the enzymes in milk. It can improve the immune function of cows.

Key words: traditional Chinese medicine; complex perfusion fluid; mastitis; SCC; lymphocyte

中图分类号:

S853.74

孟庆娟;李志明;冯士彬;王希春;韩春杨;邹松阳;刘琦山;吴金节. 中药复方灌注剂对奶牛乳房炎的防治效果及免疫增强作用[J]. , 2011, 38(7): 219-224.

MENG Qing-juan;LI Zhi-ming;FENG Shi-bin;WANG Xi-chun;HAN Chun-yang;ZOU Song-yang;LIU Qi-shan;WU Jin-jie. Prevention and Cure Effect and Immunological Enhancement of the Complex Perfusion Fluid of the Traditional Chinese Medicine to Mastitis of Dairy Cows[J]. China Animal Husbandry & Veterinary Medicine, 2011, 38(7): 219-224.

[1]	刘志旭, 韩文昌, 李彦芹, 张利文, 刘燕, 苑昭伟, 李建斌, 王晓, 曹荣峰. 山东地区隐性乳房炎牛乳中β-内酰胺酶blaZ基因与微生物相关性研究[J]. 中国畜牧兽医, 2025, 52(5): 2318-2327.
[2]	罗琴, 刘丁语, 刘宝玲, 乔常宏, 陈翔宇, 何振文, 王晓虎, 陈晶, 张翩, 黄元, 王刚, 刘昊, 蔡汝健. 不同组学视角分析中药抗病毒作用研究进展[J]. 中国畜牧兽医, 2025, 52(2): 554-561.
[3]	乔常宏, 陈翔宇, 刘宝玲, 罗琴, 刘丁语, 何振文, 王晓虎, 陈晶, 张翩, 黄元, 白挨泉, 王刚, 蔡汝健. 多组学视角下中药抗菌机制研究进展[J]. 中国畜牧兽医, 2025, 52(1): 52-59.
[4]	马洪鹏, 邵伟, 娄肖肖, 高姣姣, 马宪兰, 陈贺, 郑楠, 赵艳坤. 新疆部分地区奶牛源大肠杆菌的流行性与耐药性分析[J]. 中国畜牧兽医, 2025, 52(1): 470-480.
[5]	王美乐, 于扬帆, 徐朋, 陈青, 安珂兰·安维尔, 李姝璇, 杨松华, 尹素改, 冯书营. 非洲猪瘟病毒致病机制及防治策略研究进展[J]. 中国畜牧兽医, 2024, 51(7): 3041-3055.
[6]	鲜钰涵, 冯宏盛, 高永宇, 李海洋, 杨思宇, 桑辰君, 曹玉蝶, 唐越, 李子彬, 高凤山. 猪源病毒细胞毒性T淋巴细胞表位研究进展[J]. 中国畜牧兽医, 2024, 51(7): 3086-3099.
[7]	高庆羽, 符乐, 石玉祥, 李杰峰, 刘嫣然, 秦立佳, 张华莹, 何团拥, 王晓芳. 中药组方对大肠杆菌致小鼠腹泻治疗效果研究[J]. 中国畜牧兽医, 2024, 51(6): 2661-2670.
[8]	董媛, 王嘉宁, 刘佳琪, 马广辉, 朱洁, 于欢, 王会岩. 复方中药制剂对H22荷瘤小鼠免疫功能的影响[J]. 中国畜牧兽医, 2024, 51(6): 2717-2725.
[9]	张腾龙, 郭晨阳, 钟华晨, 刘嘉琳, 宋洁, 王丽芳. 蒲公英和连翘提取物对隐性乳房炎奶牛生产性能、血清抗氧化及免疫指标的影响[J]. 中国畜牧兽医, 2024, 51(4): 1490-1499.
[10]	王建东, 丁辉, 刘欣, 侯鹏霞, 梁小军, 高海慧, 王瑞刚, 姜武. 葡萄渣对肉母牛外周血淋巴细胞亚群、淋巴细胞转化率与凋亡率及抗氧化性的影响[J]. 中国畜牧兽医, 2024, 51(4): 1530-1536.
[11]	王玉, 石嵩, 靳盼豪, 李金昕, 张洺溪, 李托, 李陇平, 屈雷, 董书伟. 榆林部分地区湖羊乳房炎病原菌的分离鉴定及耐药性和毒力基因检测[J]. 中国畜牧兽医, 2024, 51(4): 1746-1756.
[12]	王士勇, 苏东雪, 张靖, 陈丽红, 詹军, 陈尧, 文盛鸿, 杨月春. 复方中药提取物对公兔生殖生理的影响[J]. 中国畜牧兽医, 2024, 51(3): 1122-1131.
[13]	产燕子, 王馨悦, 李思菡, 王俊凯, 王宇艳, 胡铁生, 莫桂芬, 梁德宏, 石达友. 复方中药对强制换羽蛋鸡生产性能及生殖功能的影响[J]. 中国畜牧兽医, 2024, 51(3): 1151-1159.
[14]	李俊贤, 任涛, 杨剑, 郭杨, 文安林, 欧德渊. 抗鸡传染性支气管炎病毒中药的筛选[J]. 中国畜牧兽医, 2024, 51(3): 1241-1249.
[15]	何兴丽, 王昭元, 周佩瑶, 牟泉宙, 沈冰蕾. 奶牛乳房炎金黄色葡萄球菌免疫逃避机制研究进展[J]. 中国畜牧兽医, 2024, 51(2): 748-758.