›› 2009, Vol. 36 ›› Issue (10): 193-197.

• 经验交流 • 上一篇    下一篇

鸡粪便中氧氟沙星的降解动态研究

潘孝成1,张丹俊1,程宝艳1,赵瑞宏1,许世富2,汤春莲2,胡晓苗1,詹凯1,孙军霞3   

  1. (1.安徽省农业科学院畜牧兽医研究所, 合肥 230031; 2.安徽省兽药饲料监察所, 合肥 230022;3.安徽铜陵正强禽业, 铜陵 244100)
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2009-10-20 发布日期:2009-10-20
  • 通讯作者: 张丹俊

Study on Degradation of Ofloxacin in Excrements of Chicken

PAN Xiao-cheng1, ZHANG Dan-jun1, CHENG Bao-yan1, ZHAO Rui-hong1, XU Shi-fu2, TANG Chun-lian2, HU Xiao-miao1, ZHAN Kai1, SUN Jun-xia3   

  1. (1.Institute of Animal and Veterinary Science, Anhui Academy of Agricultural Science, Hefei 230031, China; 2.Anhui Provincial Control Institute of Veterinary Pharmaceuticals and Feed, Hefei 230022, China; 3.Tongling Zhengqiang Poultry Company,Tongling 244100, China)
  • Received:1900-01-01 Revised:1900-01-01 Online:2009-10-20 Published:2009-10-20
  • Contact: ZHANG Dan-jun

摘要: 氧氟沙星(Ofloxacin,OFL)是畜禽养殖业中最常使用的抗菌药物之一,其在粪便中的残留会对微生态环境产生不利影响。本试验对3种条件下鸡粪便中氧氟沙星的降解进行了研究,结果显示,室温避光条件下,鸡粪便中氧氟沙星几乎不降解,发酵条件下OFL的降解很慢,自然光照时OFL的降解较快。 OFL降解的变化趋势符合一级动力学方程Ct=C0e-kt,根据此方程求得光照条件下的OFL降解半衰期为(5.77±0.466) d, 发酵条件下的OFL降解半衰期为(35.66±1.99) d。

关键词: 鸡; 粪便; 氧氟沙星; 降解

Abstract: Ofloxacin is one of the most widely used antibiotics in the livestock and poultry industry, its residue in the excrement will has the adverse effect to the environment. Ofloxacin’s degeneration in the chicken excrement had been studied in different conditions. The results showed that ofloxacin in chicken excrement was very stable in photophobic condition, the degradation rate of ofloxacin was slow in the chicken excrement of fermentation,but under daylight illumination, the degradation rate of ofloxacin was high in chicken excrement.The degradation process of ofloxacin in chicken excrement could be evaluated on the basis of the first order kinetic equation as Ct=C0e-kt. Calculated by this equation, the half-life of ofloxacin in chicken excrement was (5.77±0.466) d under daylight illumination. The half-life of ofloxacin was (35.66±1.99) d in chicken excrement of fermentation.

Key words: chicken; ofloxacin; excrement; degeneration

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