›› 2013, Vol. 40 ›› Issue (10): 211-215.

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Investigation of Antibiotic Resistance among Escherichia coli Isolated from Different Animals

HE Dan-dan1, HUANG Liang-zong2, CHEN Xiao-jie1, YANG Tong1, RAO Li-li1, LUO Dong-mei1, CHEN Pei-ling1, PENG Hui1, LIU Jian-hua1   

  1. 1. Guangdong Key Laboratory for Veterinary Drug Development and Safety Evaluation, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China;
    2. Foshan University, Foshan 528000, China
  • Received:2013-03-27 Online:2013-10-20 Published:2013-12-19

Abstract: To determine the resistance of Escherichia coli strains to kinds of antimicrobials, a total of 935 Escherichia coli isolates were collected from diseased and healthy food-producing animals during 2011 to 2012, which contained 606 E.coli strains from healthy swine, 114 from diseased swine, 51 from diseased chicken and 164 from diseased water fowl(duck and goose).The susceptibility of 935 isolates to 15 antimicrobials were determined by agar dilution method. The results showed that the resistance of the isolates was serious.The resistance rates to most of the antimicrobials were over 70.0%, especially ampicillin, sulfamethoxazole/trimethoprim and tetracycline, with resistance rates of over 80.0%. There was a relative low frequency of cefoxitin, colistin and amikacin among these isolates, except that the resistance rate(52.4%) to amikacin in Escherichia coli from diseased water fowl was higher than other animals distinctly. The resistance rates of the isolates from diseased animals to most of the antimicrobials were significantly higher than those from healthy animals, which indicated that the use of antimicrobials increased the resistance rates of the isolates to quinolones and the third cephalosporinases, that would increase the difficult of the clinical treatment.

Key words: Escherichia coli; antibiotic resistance; multiple resistance

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