小花棘豆总黄酮体内抗氧化作用的研究

Abstract

Abstract: The purpose of this project was to study the anti-oxidant activity in vivo of total flavonoids from Oxytropis glabra DC. Ultrasonic-assisted extraction was adopted to extract total flavonoids from Oxytropis glabra DC. Mice model of carbon tetrachloride (CCl₄) liver injury was used to assay the antioxidant ability in vivo of total flavonoids. In mice serum and liver, total flavnoids from Oxytropis glabra DC could markedly increase the activity of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px), and decrease the content of maleic dialdehyde (MDA) and lipofuscim(LP). Therefore, total flavnoids from Oxytropis glabra DC had antioxidant activity in vivo to some extant, which provided for its further developing and researching.

Key words: Oxytropis glabra DC; total flavonoids; antioxidant activity in vivo

CLC Number:

S452

WANG Shuai, CHEN Gen-yuan, JIANG Hui, XI Lin-qiao, ZHANG Ling, MA Chun-hui. Study on Antioxidative Activities in vivo of Total Flavonoids from Oxytropis Glabra DC[J]. , 2012, 39(10): 133-136.

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Study on Antioxidative Activities in vivo of Total Flavonoids from Oxytropis Glabra DC

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