›› 2011, Vol. 38 ›› Issue (2): 64-67.

• 生物技术 • Previous Articles     Next Articles

RNA Interference Technique and its Application to Studies of Parasitic Nematode

CHEN Nan-ying1,2,HE Yan-hua1,BO Xin-wen1,WANG Xin-hua1   

  1. (1.The Breed and Biotechnology Key Laboratory of Sheep in Reproduction and Construction Group of Xinjiang,Xinjiang Academy of Agricultural and Reclamation Science, Shihezi 832000,China;2.College of Animal Science and Technology, Shihezi University,Shihezi 832003,China)
  • Received:1900-01-01 Revised:1900-01-01 Online:2011-02-20 Published:2011-02-20
  • Contact: WANG Xin-hua

Abstract: RNA interference(RNAi) technique is a gene silencing technology. It causes post transcriptional gene silence by inducing degradation of mRNA of specific target sequence. The technology is now widely used in studies of genome function and gene therapy of certain diseases. In this article, the formation mechanism, function characteristics, research strategies of RNAi and the application in the studies of parasitic nematodes will be expatiated.

Key words: RNA interference; parasitic nematode; application

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