超氧化物歧化酶的生理功能及其在动物生产中的应用前景

doi:10.16431/j.cnki.1671-7236.2024.03.006

Abstract

Abstract: Oxidative stress can lead to the imbalance between oxidation and antioxidation in the body,resulting in excessive reactive oxygen species (ROS),causing damage to cells and tissues,inflammation and other diseases,affecting the growth and development of the body.Superoxide dismutase (SOD) is an antioxidant metal enzyme that exists in living organisms.It can catalyze superoxide anion radical (O₂^―) through disproportionation reaction,thereby eliminating excessive ROS in animals.Studies have found that SOD not only has a specific and high efficiency in antioxidant function,slows down the aging of the body,but also improves the intestinal health production performance of animals and regulates the immune function of the body to a certain extent.In the case of large-scale use of intensive livestock and poultry breeding and production machines,the damage caused by radiation to animals needs to be paid attention to.Effectively utilizing the anti-radiation function of SOD to alleviate or improve the impact of radiation on the body is worth further exploration.At present,the main additives for relieving oxidative stress of the body are vitamins,trace elements,plant extracts,etc.,while the use of SOD to relieve oxidative stress and improve production performance of animals is relatively few studies,mainly due to the high extraction cost,large molecular weight,easy inactivation of natural SOD.However,with the emergence of synthetic SOD,the cost of preparing SOD is reduced,and it has the characteristics of high activity and easy absorption of small molecules,which makes the application of SOD in livestock and poultry production gradually increase,and more potential of SOD can be tapped in the future,and SOD can be more widely used in animal production.In this paper,the physiological functions of SOD such as anti-oxidation,anti-aging,anti-inflammation,anti-radiation and regulating immunity were summarized,in order to provide more theoretical basis for the application of SOD in animal production.

Key words: superoxide dismutase (SOD); physiological function; animal production; application

CLC Number:

S816.7

JIANG Huiqiong, LIU Yating, CHEN Qinghua. Physiological Function of Superoxide Dismutase and Its Application Prospect in Animal Production[J]. China Animal Husbandry and Veterinary Medicine, 2024, 51(3): 945-954.

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Physiological Function of Superoxide Dismutase and Its Application Prospect in Animal Production

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