Abstract: Equine,especially sport horses,tend to suffer from locomotor system injury.Once the injury occurs,it will lead to varying degrees of lameness,and it is difficult to completely repair the damaged tissue,which often leads to a significant decline in horse motor performance and poor prognosis,and is one of the main reasons for the early end of sports career of sports horses.Platelet-rich plasma (PRP) is a regenerative medicine formulation that promotes tissue repair and regeneration by activating platelets to release large amounts of growth factors.Many studies and clinical reports have shown that PRP has a certain therapeutic effect on locomotor injuries,and is most commonly used in the treatment of equine tendon,ligament injury and osteoarthritis,and is widely used in Europe and the United States and other countries.In addition,PRP also has certain antibacterial effect and is expected to be used in the treatment of septic arthritis.It also shows a certain therapeutic potential for laminitis and other diseases with limited response of traditional treatment.In the field of equine sports medicine,the mechanism and scope of application of PRP are not well understood in China,and there is a lack of research reports on the use of PRP in the treatment of equine locomotor system injury in clinical practice.The author reviewed the preparation and classification of PRP,the clinical application and research progress of PRP in the treatment of equine locomotor system injury,and summarized the application scope and development trend of PRP in the treatment of equine locomotor system injury,in order to provide references for domestic veterinarians and related practitioners to apply PRP.

Key words: equine; platelet-rich plasma; locomotor system injuries; clinical application