›› 2011, Vol. 38 ›› Issue (2): 125-127.

• 遗传繁育 • Previous Articles     Next Articles

Genetic Variations in Porcine Erythropoietin Receptor Gene

ZHANG Long-chao, WANG Li-gang, ZHAO Ke-bin, LI Yong, YAN Hua, WANG Li-xian   

  1. (Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China)
  • Received:1900-01-01 Revised:1900-01-01 Online:2011-02-20 Published:2011-02-20

Abstract: In this study, 8 pair primers were designed based on erythropoietin receptor (EPOR) RNA (AF274305) and DNA (EU407778) sequences in porcine which were submitted on GenBank. Genetic variation was analyzed by sequencing using a DNA pool from 10 Beijing Black pigs and 10 Large white pigs. The results showed that the porcine EPOR gene contains one 5′untranslated region (UTR), eight exons, seven introns, and one 3′UTR, covering at least 5.2 kb of genomic DNA. 9 new single nucleotide polymorphisms (SNPs) were identified: g.705G>T in intron 1, g.1450C>T in intron 2, g.2373C>T in intron 4, and g.2882C>T, g.3035A>G, g.3132A>T, g.3295C>T, g.3942C>>T and g.4106G>A in intron 6.

Key words: pig; EPOR gene; genetic variation

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