非编码RNA与骨骼肌发育研究进展

doi:10.16431/j.cnki.1671-7236.2020.11.020

Abstract

Abstract: Skeletal muscle is an important tissue of the vertebrate body,its embryonic development starts from the proliferation and differentiation of myogenic progenitor cells of the dermomyotome into myoblasts,and further develops to form myotubes and eventually form muscle fibers.The entire development process is subject to complex and tight regulation,any abnormal regulation may affect the normal development process of skeletal muscle.In recent years,studies have shown that,in addition to myogenic regulator factors,myocyte enhancer factors and paired box proteins,non-coding RNA includes microRNA (miRNA),long noncoding RNA (lncRNA)and circular RNA (circRNA) can be widely used as important regulators to participate in the regulation of skeletal muscle development.miRNA mainly acts on target mRNA,and regulates the expression of related genes at the post-transcription level by inducing the destabilization of target mRNA and/or inhibiting translation.lncRNA has long length and advanced structure,which can regulate the expression of related genes in both pre-transcriptional and post-transcriptional levels through a variety of action modes.circRNA is mainly used as a miRNAs ponge,competitively binds to miRNA,and participates in the regulatory network of skeletal muscle development.The author summarized the seven aspects of skeletal muscle development,miRNA mechanism,miRNA and skeletal muscle development,lncRNA mechanism,lncRNA and skeletal muscle development,circRNA mechanism and circRNA and skeletal muscle development,in order to provide reference for studying the regulation of non-coding RNA in skeletal muscle development.

Key words: skeletal muscle development; miRNA; lncRNA; circRNA

CLC Number:

Q527⁺.3

BAI Fengting, LI Lin, CHEN Junhao, ZHAO Bei, PENG Xinyu, WANG Yanhong, FANG Xingtang, ZHANG Chunlei, SONG Chengchuang. Research Progress on Non-coding RNA and Skeletal Muscle Development[J]. China Animal Husbandry and Veterinary Medicine, 2020, 47(11): 3584-3594.

References

[1] HORAK M,NOVAK J,BIENERTOVA-VASKU J.Muscle-specific microRNAs in skeletal muscle develop-ment[J].Developmental Biology,2016,410(1):1-13.
[2] MOLKENTIN J D,FIRULLI A B,BLACK B L,et al.MEF2B is a potent transactivator expressed in early myogenic lineages[J].Molecular and Cellular Biology,1996,16(7):3814-3824.
[3] MOLKENTIN J D,BLACK B L,MARTIN J F,et al.Cooperative activation of muscle gene expression by MEF2 and myogenic bHLH proteins[J].Cell,1995,83(7):1125-1136.
[4] RELAIX F,ROCANCOURT D,MANSOURI A,et al.A Pax3/Pax7-dependent population of skeletal muscle progenitor cells[J].Nature,2005,435(7044):948-953.
[5] DE RIE D,ABUGESSAISA I,ALAM T,et al.An integrated expression atlas of miRNAs and their promoters in human and mouse[J].Nature Biotechnology,2017,35(9):872-878.
[6] DUCHAINE T F,FABIAN M R.Mechanistic insights into microRNA-mediated gene silencing[J].Cold Spring Harb Perspect Biology,2019,11(3):a032771.
[7] MOHR A,MOTT J.Overview of microRNA biology[J].Seminars in Liver Disease,2015,35(1):3-11.
[8] JO M H,SHIN S,JUNG S-R,et al.Human argonaute 2 has diverse reaction pathways on target RNAs[J].Molecular Cell,2015,59(1):117-124.
[9] DYKES I M,EMANUELI C.Transcriptional and post-transcriptional gene regulation by long non-coding RNA[J].Genomics Proteomics Bioinformatics,2017,15(3):177-186.
[10] MA L N,BAJIC V B,ZHANG Z.On the classification of long non-coding RNAs[J].RNA Biology,2013,10(6):925-933.
[11] BI P,RAMIREZ-MARTINEZ A,LI H,et al.Control of muscle formation by the fusogenic micropeptide myomixer[J].Science,2017,356(6335):323-327.
[12] KRISTENSEN L S,ANDERSEN M S,STAGSTED L V W,et al.The biogenesis,biology and characterization of circular RNAs[J].Nature Reviews Genetics,2019,20(11):675-691.
[13] 齐玉涵,刘泽鹏,张伟杰,等.环形RNA研究进展[J].生理学报,2019,71(4):613-624. QI Y H,LIU Z P,ZHANG W J,et al.Research advance in circular RNAs[J].Acta Physiologica Sinica,2019,71(4):613-624.(in Chinese)
[14] LI Z Y,HUANG C,BAO C,et al.Exon-intron circular RNAs regulate transcription in the nucleus[J].Nature Structural & Molecular Biology,2015,22(3):256-264.
[15] CHEN N F,ZHAO G,YAN X,et al.A novel FLI1 exonic circular RNA promotes metastasis in breast cancer by coordinately regulating TET1 and DNMT1[J].Genome Biology,2018,19(1):218.
[16] CONN V M,HUGOUVIEUX V,NAYAK A,et al.A circRNA from SEPALLATA3 regulates splicing of its cognate mRNA through R-loop formation[J].Nature Plant,2017,3:17053.
[17] LI X,YANG L,CHEN L L.The biogenesis,functions,and challenges of circular RNAs[J].Molecular Cell,2018,71(3):428-442.
[18] THOMSDN D W,DINGER M E.Endogenous microRNA sponges:Evidence and controversy[J].Nature Reviews Genetics,2016,17(5):272-283.
[19] SIRACUSA J,KOULMANN N,BANZET S.Circulating myomiRs:A new class of biomarkers to monitor skeletal muscle in physiology and medicine[J].Journal of Cachexia,Sarcopenia and Muscle,2018,9(1):20-27.
[20] CHEN J F,MANDEL E M,THOMSON J M,et al.The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation[J].Nature Genetics,2005,38(2):228-233.
[21] WINBANKS C E,WANG B,BEYER C,et al.TGF-β regulates miR-206 and miR-29 to control myogenic differentiation through regulation of HDAC4[J].The Journal of Biological Chemistry,2011,286(16):13805-13814.
[22] SUN Y T,GE Y J,DRNEVICH J,et al.Mammalian target of rapamycin regulates miRNA-1 and follistatin in skeletal myogenesis[J].The Journal of Cell Biology,2010,189(7):1157-1169.
[23] GOLJANEK-WHYSALL K,SWEETMAN D,ABU-ELMAGD M,et al.microRNA regulation of the paired-box transcription factor Pax3 confers robustness to developmental timing of myogenesis[J].Proceedings of the National Academy of Sciences of the United States of America,2011,108(29):11936-11941.
[24] WANG D Z,XIAO X,YAN Z,et al.microRNA-1 and microRNA-206 regulate skeletal muscle satellite cell proliferation and differentiation by repressing Pax7[J].Journal of Cell Biology,2010,190(5):867-879.
[25] BJORNSON C R,CHEUNG T H,LIU L,et al.Notch signaling is necessary to maintain quiescence in adult muscle stem cells[J].Stem Cells,2012,30(2):232-242.
[26] GAGAN J,DEY B K,LAYER R,et al.Notch3 and Mef2c proteins are mutually antagonistic via Mkp1 protein and miR-1_206 microRNAs in differentiating myoblasts[J].Journal of Biological Chemistry,2012,287(48):40360-40370.
[27] GOLJANEK-WHYSALL K,MOK G F,FAHAD A A,et al.MyomiR-dependent switching of BAF60 variant incorporation into Brg1 chromatin remodeling complexes during embryo myogenesis[J].Development,2014,141(17):3378-3387.
[28] FENG Y,NIU L L,WEI W,et al.A feedback circuit between miR-133 and the ERK1/2 pathway involving an exquisite mechanism for regulating myoblast proliferation and differentiation[J].Cell Death and Disease,2013,4:e934.
[29] MOK G F,LOZANO-VELASCO E,MANIOU E,et al.miR-133-mediated regulation of the Hedgehog pathway orchestrates embryo myogenesis[J].Development,2018,145(12):dev159657.
[30] DEY B K,GAGAN J,DUTTA A,et al.miR-206 and -486 induce myoblast differentiation by downregulating Pax7[J].Molecular and Cellular Biology,2011,31(1):203-214.
[31] SMALL E M,O'ROURKE J R,MORESI V,et al.Regulation of PI3-kinase/Akt signaling by muscle-enriched microRNA-486[J].Proceedings of the National Academy of Sciences of the United States of America,2010,107(9):4218-4223.
[32] CAI B L,MA M T,CHEN B,et al.miR-16-5p targets SESN1 to regulate the p53 signaling pathway,affecting myoblast proliferation and apoptosis,and is involved in myoblast differentiation[J].Cell Death & Disease,2018,9(3):367.
[33] SONG C C,YANG Z X,DONG D,et al.miR-483 inhibits bovine myoblast cell proliferation and differentiation via IGF1/PI3K/AKT signal pathway[J].Journal of Cellular Physiology,2019,234(6):9839-9848.
[34] KONG D L,HE M,YANG L,et al.miR-17 and miR-19 cooperatively promote skeletal muscle cell differentia-tion[J].Cellular and Molecular Life Sciences,2019,76(24):5041-5054.
[35] GE G H,YANG D L,TAN Y,et al.miR-10b-5p regulates C2C12 myoblasts proliferation and differentiation[J].Bioscience,Biotechnology,and Biochemistry,2019,83(2):291-299.
[36] WANG H,ZHANG Q,WANG B B,et al.miR-22 regulates C2C12 myoblast proliferation and differentiation by targeting TGFBR1[J].European Journal of Cell Biology,2018,97(4):257-268.
[37] YIN H D,HE H R,SHEN X X,et al.miR-9-5p inhibits skeletal muscle satellite cell proliferation and differentiation by targeting IGF2BP3 through the IGF2-PI3K/Akt signaling pathway[J].International Journal of Molecular Sciences,2020,21(5):1655.
[38] HOU L J,XU J,JIAO Y R,et al.miR-27b promotes muscle development by inhibiting MDFI expression[J].Cellular Physiologyand Biochemistry,2018,46(6):2271-2283.
[39] IBRAHIM E E,DONG D,WANG X,et al.Bta-miR-885 promotes proliferation and inhibits differentiation of myoblasts by targeting MyoD1[J].Journal of Cellular Physiology,2020,Online ahead of print.
[40] DU J J,ZHANG P W,ZHAO X,et al.microRNA-351-5p mediates skeletal myogenesis by directly targeting lactamase-β and is regulated by lnc-mg[J].The FASEB Journal,2019,33(2):1911-1926.
[41] GE J,ZHU J Y,XIA B,et al.miR-423-5p inhibits myoblast proliferation and differentiation by targeting Sufu[J].Journal of Cellular Biochemistry,2018,119(9):7610-7620.
[42] QIN J,SUN Y M,LIU S G,et al.microRNA-323-3p promotes myogenesis by targeting Smad2[J].Journal of Cellular Biochemistry,2019,120(11):18751-18761.
[43] WU J Y,YUE B L,LAN X Y,et al.miR-499 regulates myoblast proliferation and differentiation by targeting transforming growth factor β receptor 1[J].Journal of Cellular Physiology,2019,234(3):2523-2536.
[44] WANG J,SONG C C,CAO X K,et al.miR-208b regulates cell cycle and promotes skeletal muscle cell proliferation by targeting CDKN1A[J].Journal of Cellular Physiology,2019,234(4):3720-3729.
[45] WANG J,TAN J Y,QI Q,et al.miR-487b-3p suppresses the proliferation and differentiation of myoblasts by targeting IRS1 in skeletal muscle myogenesis[J].International Journal of Biological Sciences,2018,14(7):760-774.
[46] HOU L J,ZHU L H,LI H Q,et al.miR-501-3p forms a feedback loop with FOS,MDFI,and MyoD to regulate C2C12 myogenesis[J].Cells,2019,8(6):573.
[47] LU Z K,DU L X,LIU R Z,et al.miR-378 and BMP-Smad can influence the proliferation of sheep myoblast[J].Gene,2018,674:143-150.
[48] GAN M L,DU J J,SHEN L Y,et al.miR-152 regulates the proliferation and differentiation of C2C12 myoblasts by targeting E2F3[J].In Vitro Cellular & Developmental Biology Animal,2018,54(4):304-310.
[49] CAI R,NAREN Q,MA M L,et al.Wnt1 microRNA-664-5p promotes myoblast proliferation and inhibits myoblast differentiation by targeting serum response factor and Wnt1[J].The Journal of Biological Chemistry,2018,293(50):19177-19190.
[50] YUAN R Q,ZHANG X M,FANG Y,et al.miR-127-3p inhibits the proliferation of myocytes by targeting KMT5a[J].Biochemical and Biophysical Research Communications,2018,503(2):970-976.
[51] HUANG W L,GUO L J,ZHAO M X,et al.The inhibition on MDFIC and PI3K/AKT pathway caused by miR-146b-3p triggers suppression of myoblast proliferation and differentiation and promotion of apoptosis[J].Cells,2019,8(7):656.
[52] HU X,XING Y S,REN L,et al.ACVR1BBta-miR-24-3p controls the myogenic differentiation and proliferation of fetal,bovine,skeletal muscle-derived progenitor cells by targeting[J].Animals:An Open Access Journal from MDPI,2019,9(11):859.
[53] LI X,ZHU Y B,ZHANG H F,et al.microRNA-106a-5p inhibited C2C12 myogenesis via targeting PIK3R1 and modulating the PI3K/AKT signaling[J].Genes,2018,9(7):333.
[54] LING Y H,SUI M H,ZHENG Q,et al.miR-27b regulates myogenic proliferation and differentiation by targeting Pax3 in goat[J].Scientific Reports,2018,8(1):3909.
[55] WANG Z J,ZHANG X C,LI Z H,et al.miR-34b-5p mediates the proliferation and differentiation of myo-blasts by targeting IGFBP2[J].Cells,2019,8(4):360.
[56] YANG Z X,SONG C C,JIANG R,et al.micro-ribonucleic acid-216a regulates bovine primary muscle cells proliferation and differentiation via targeting SMAD nuclear interacting protein-1 and Smad7[J].Frontiers in Genetics,2019,10:1112.
[57] ZHOU S,LI S,ZHANG W W,et al.miR-139 promotes differentiation of bovine skeletal muscle-derived satellite cells by regulating DHFR gene expression[J].Journal of Cell Physiology,2018,234(1):632-641.
[58] ZHU L H,HOU L J,OU J X,et al.miR-199b represses porcine muscle satellite cells proliferation by targeting JAG1[J].Gene,2019,691:24-33.
[59] YU X H,ZHANG Y,LI T T,et al.Long non-coding RNA linc-RAM enhances myogenic differentiation by interacting with MyoD[J].Nature Communications,2017,8:14016.
[60] CARETTI G,LOUIS SCHILJZ R,JEFFREY DILWORTH F,et al.The RNA helicases p68/p72 and the noncoding RNA SRA are coregulators of MyoD and skeletal muscle differentiation[J].Developmental Cell,2006,11(4):547-560.
[61] MOUSAVI K,ZARE H,DELL'ORSO S,et al.eRNAs promote transcription by establishing chromatin accessibility at defined genomic loci[J].Molecular Cell,2013,51(5):606-617.
[62] WANG L J,ZHAO Y,BAO X C,et al.lncRNA Dum interacts with Dnmts to regulate Dppa2 expression during myogenic differentiation and muscle regeneration[J].Cell Research,2015,25(3):335-350.
[63] JIN J J,LV W,XIA P,et al.Long noncoding RNA SYISL regulates myogenesis by interacting with polycomb repressive complex 2[J].Proceedings of the National Academy of Sciences of the United States of America,2018,115(42):E9802-E9811.
[64] WANG S S,ZUO H,JIN J J,et al.Long noncoding RNA Neat1 modulates myogenesis by recruiting Ezh2[J].Cell Death & Disease,2019,10(7):505.
[65] KANG X D,ZHAO Y,ARSDELL G V,et al.Ppp1r1b-lncRNA inhibits PRC2 at myogenic regulatory genes to promote cardiac and skeletal muscle development in mouse and human[J].RNA (New York,N.Y.),2020,26(4):481-491.
[66] CHEN X N,HE L Q,ZHAO Y,et al.Malat1 regulates myogenic differentiation and muscle regeneration through modulating MyoD transcriptional activity[J].Cell Discovery,2017,3:17002.
[67] ZHOU Y L,CHEUNSUCHON P,NAKAYAMA Y,et al.Activation of paternally expressed genes and perinatal death caused by deletion of the Gtl2 gene[J].Development,2010,137(16):2643-2652.
[68] ZHAO J,OHSUMI T K,KUNG J T,et al.Genome-wide identification of polycomb-associated RNAs by RIP-seq[J].Molecular Cell,2010,40(6):939-953.
[69] ZHOU L,SUN K,ZHAO Y,et al.Linc-YY1 promotes myogenic differentiation and muscle regeneration through an interaction with the transcription factor YY1[J].Nature Communications,2015,6:10026.
[70] MILITELLO G,HOSEN M R,PONOMAREVA Y,et al.A novel long non-coding RNA myolinc regulates myogenesis through TDP-43 and Filip1[J].Journal of Molecular Cell Biology,2018,10(2):102-117.
[71] HITACHI K,NAKATANI M,TAKASAKI A,et al.Myogenin promoter-associated lncRNA Myoparr is essential for myogenic differentiation[J].EMBO Report,2019,20(3):e47468.
[72] SUI Y T,HAN Y,ZHAO X Y,et al.Long non-coding RNA Irm enhances myogenic differentiation by interacting with MEF2D[J].Cell Death & Disease,2019,10(3):181.
[73] KALLEN A N,ZHOU X B,XU J,et al.The imprinted H19 lncRNA antagonizes let-7 microRNAs[J].Molecular Cell,2013,52(1):101-112.
[74] CESANA M,CACCHIARELLI D,LEGNINI I,et al.A long noncoding RNA controls muscle differentiation by functioning as a competing endogenous RNA[J].Cell,2011,147(2):358-369.
[75] ZHANG Z K,LI J,GUAN D G,et al.A newly identified lncRNA MAR1 acts as a miR-487b sponge to promote skeletal muscle differentiation and regeneration[J].Journal of Cachexia, Sarcopenia Muscle,2018,9(3):613-626.
[76] ZHU M,LIU J F,XIAO J,et al.lnc-mg is a long non-coding RNA that promotes myogenesis[J].Nature Communications,2017,8:14718.
[77] SONG C C,WANG J,MA Y L,et al.Linc-smad7 promotes myoblast differentiation and muscle regeneration via sponging miR-125b[J].Epigenetics,2018,13(6):591-604.
[78] ZHANG Z K,LI J,GUAN D G,et al.Long non-coding RNA lncMUMA reverses established skeletal muscle atrophy following mechanical unloading[J].Molecular Therapy,2018,26(11):2669-2680.
[79] LI H,YANG J M,JIANG R,et al.Long non-coding RNA profiling reveals an abundant MDNCR that promotes differentiation of myoblasts by sponging miR-133a[J].Molecular Therapy Nucleic Acids,2018,12:610-625.
[80] WANG G Q,WANG Y,XIONG Y,et al.Sirt1 AS lncRNA interacts with its mRNA to inhibit muscle formation by attenuating function of miR-34a[J].Scientific Reports,2016,6:21865.
[81] LIANG T T,ZHOU B,SHI L,et al.lncRNA AK017368 promotes proliferation and suppresses differentiation of myoblasts in skeletal muscle development by attenuating the function of miR-30c[J].The FASEB Journal,2017,32(1):377-389.
[82] HAN X R,YANG F,CAO H Q,et al.Malat1 regulates serum response factor through miR-133 as a competing endogenous RNA in myogenesis[J].The FASEB Journal,2015,29(7):3054-3064.
[83] LU L N,SUN K,CHEN X N,et al.Genome-wide survey by ChIP-seq reveals YY1 regulation of lincRNAs in skeletal myogenesis[J].The EMBO Journal,2013,32(19):2575-2588.
[84] GONG C G,LI Z Z,RAMANUJAN K,et al.A long non-coding RNA,lncMyoD,regulates skeletal muscle differentiation by blocking IMP2-mediated mRNA transla-tion[J].Developmental Cell,2015,34(2):181-191.
[85] ZHANG Q,VASHISHT A A,O'ROURKE J,et al.The microprotein minion controls cell fusion and muscle formation[J].Nature Communications,2017,8:15664.
[86] QUINN M E,GOH Q,KUROSAKA M,et al.Myomerger induces fusion of non-fusogenic cells and is required for skeletal muscle development[J].Nature Communications,2017,8:15665.
[87] OUYANG H J,CHEN X L,LI W M,et al.Circular RNA circSVIL promotes myoblast proliferation and differentiation by sponging miR-203 in chicken[J].Frontiers in Genetics,2018,9:172.
[88] CHEN X L,OUYANG H J,WANG Z J,et al.A novel circular RNA generated by FGFR2 gene promotes myoblast proliferation and differentiation by sponging miR-133a-5p and miR-29b-1-5p[J].Cells,2018,7(11):199.
[89] CHEN B,YU J,GUO L J,et al.Circular RNA circHIPK3 promotes the proliferation and differentiation of chicken myoblast cells by sponging miR-30a-3p[J].Cells,2019,8(2):177.
[90] WANG X G,CAO X K,DONG D,et al.Circular RNA TTN acts as a miR-432 sponge to facilitate proliferation and differentiation of myoblasts via the IGF2/PI3K/AKT signaling pathway[J].Molecular Therapy Nucleic Acids,2019,18:966-980.
[91] YUE B L,WANG J,RU W X,et al.The circular RNA circHUWE1 sponges the miR-29b-AKT3 axis to regulate myoblast development[J].Molecular Therapy Nucleic Acids,2020,19:1086-1097.
[92] LI H,YANG J M,WEI X F,et al.circFUT10 reduces proliferation and facilitates differentiation of myoblasts by sponging miR-133a[J].Journal of Cell Physiology,2018,233(6):4643-4651.
[93] LI X Y,LI C Y,LIU Z J,et al.Circular RNA circ-FoxO3 inhibits myoblast cells differentiation[J].Cells,2019,8(6):616.
[94] PENG S J,SONG C C,LI H,et al.Circular RNA SNX29 sponges miR-744 to regulate proliferation and differentiation of myoblasts by activating the Wnt5a/Ca²⁺signaling pathway[J].Molecular Therapy. Nucleic Acids,2019,16:481-493.
[95] WEI X F,LI H,YANG J M,et al.Circular RNA profiling reveals an abundant circLMO7 that regulates myoblasts differentiation and survival by sponging miR-378a-3p[J].Cell Death & Disease,2017,8(10):e3153.
[96] LI H,WEI X F,YANG J M,et al.circFGFR4 promotes differentiation of myoblasts via binding miR-107 to relieve its inhibition of Wnt3a[J].Molecular Therapy Nucleic Acids,2018,11:272-283.
[97] WANG Y H,LI M L,WANG Y H,et al.A Zfp609 circular RNA regulates myoblast differentiation by sponging miR-194-5p[J].International Journal of Biological Macromolecules,2019,121:1308-1313.
[98] LI L,CHEN Y,NIE L,et al.MyoD-induced circular RNA CDR1as promotes myogenic differentiation of skeletal muscle satellite cells[J].Biochimica et Biophysica Acta.Gene Regulatory Mechanisms,2019,1862(8):807-821.
[99] OUYANG H J,CHEN X L,WANG Z J,et al.Circular RNAs are abundant and dynamically expressed during embryonic muscle development in chickens[J].DNA Research:An International Journal for Rapid Publication of Reports on Genes and Genomes,2018,25(1):71-86.

Research Progress on Non-coding RNA and Skeletal Muscle Development

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