China Animal Husbandry and Veterinary Medicine ›› 2023, Vol. 50 ›› Issue (6): 2427-2438.doi: 10.16431/j.cnki.1671-7236.2023.06.027

• Preventive Veterinary Medicine • Previous Articles     Next Articles

Research Progress on Long Non-coding RNA of Muscle Development in Livestock and Poultry

LI Jie1,2, CHEN Chuwen1,2, ZHAO Ruipeng1,3, LIU Yuan1,2, LI Zhixiong1,2   

  1. 1. Key Laboratory of Ministry of Education for Qinghai-Tibetan Plateau Animal Genetic Resource Reservation and Utilization, Southwest Minzu University, Chengdu 610041, China;
    2. College of Animal & Veterinary Sciences, Southwest Minzu University, Chengdu 610041, China;
    3. Institute of Qinghai-Tibetan Plateau, Southwest Minzu University, Chengdu 610041, China
  • Received:2022-11-10 Online:2023-06-05 Published:2023-05-30

Abstract: The muscle of livestock and poultry is the mainly source of protein required for human life activities.Research on the growth and development of muscle is essential to improve the yield and quality of meat products in livestock and poultry.The muscle growth and development in livestock and poultry is an extremely complex process, which is regulated not only by various myogenic regulators (such as MyoD, MyoG and Myf5, etc.), but also by various non-coding RNAs (ncRNA), such as long non-coding RNA (lncRNA), microRNA (miRNA), circular RNA (circRNA), and so on.lncRNA is a type of functional ncRNA that is more than 200 nucleotides in length and lack an open reading frame (ORF), has biological functions such as interfering with gene expression, interacting with proteins, acting as ceRNA and encoding peptides.In recent years, more and more lncRNAs related to muscle growth and development in livestock and poultry have been found and identified, and the specific mechanism and function of many lncRNAs have been gradually determined.Numerous studies have confirmed that lncRNA is widely involved in many stages of muscle growth and development in livestock and poultry, and affects the yield and quality of meat in livestock and poultry.In this article, the general process of muscle growth and development in livestock and poultry, the discovery, classification, and biological functions of lncRNA were introduced, and the currently discovered lncRNA associated with muscle development in various livestock and poultry such as pigs, cattle, sheep, and chickens and their functions were reviewed.This review provided a reference for in-depth research on lncRNA in the growth and development of muscles in livestock and poultry.

Key words: long non-coding RNA (lncRNA); livestock and poultry; muscle development; growth trait

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