中兽药复方组合与抗生素防治肉鸡呼吸道疾病的协同效应

doi:10.16431/j.cnki.1671-7236.2020.03.034

Abstract

Abstract: In order to explore the synergistic effect of the combination of Chinese veterinary drugs and antibiotics on the prevention and treatment of respiratory diseases in broilers,100 three-day-old White-feather broilers were randomly selected from two chicken houses in large-scale chicken farms,which were divided into two groups (group Ⅰ and group Ⅱ).Group Ⅰ was given antibiotics in drinking water.Group Ⅱ was fed with Chinese veterinary drug Yupingfeng oral liquid (3-7 d),Shegan Dilong granule (10-16 d),Shuanghuanglian oral liquid (22-25 d),Maxingshigan oral liquid (27-31 d) in different stages on the basis of adding antibiotics.Chicken infectious bronchitis live vaccine,Newcastle disease-infectious bronchitis combined live vaccine and Newcastle disease-avian influenza two inactivated vaccine were vaccinated at 8-day-old.Serum and tracheal tissues were collected at 1,7,14,21 and 28 days after immunization to detect antibody levels of Newcastle disease,avian influenza (H9),and infectious bronchitis vaccines,observe pathological changes of tracheal tissues,and calculate the immune organ index and average daily gain,and record the incidence rate.The results showed that the survival rate of group Ⅱ increased by 1.23% compared with group Ⅰ.The final weight and average daily weight of group Ⅱ were extremely significantly higher than that of group Ⅰ (P<0.01),which increased by 561.25 g and 16.63 g/d,respectively.The respiratory symptoms of group Ⅱ were lighter than that of group Ⅰ,the course of disease was short,and there were no obvious lesions in liver and heart.The spleen index was significantly higher than that of group Ⅰ at 36 d (P<0.05).At 21 days after immunization,the antibody levels of Newcastle disease,infectious bronchitis and avian influenza (H9) vaccine in group Ⅱ reached the highest level,which was significantly higher than group Ⅰ (P<0.05).The level of Newcastle disease antibody in group Ⅱ was extremely significantly higher than that of group Ⅰ(P<0.01) at 28 days after immunization.In summary,the combination of four kinds of Chinese veterinary drugs,which clearing heat-toxin,relieving cough and asthma,clearing liver and gallbladder,combined with antibiotic had synergistic effect on promoting growth and prevention of respiratory diseases in broilers.

Key words: Chinese veterinary medicine compounds; tracheal tissue; antibiotics; White-feather broiler

CLC Number:

S858.31

FENG Haipeng, XIN Ruihua, ZHANG Kai, WANG Lei, ZHANG Kang, LI Jianxi, WANG Xuezhi. Synergistic Effect of Combination of Chinese Veterinary Drugs and Antibiotics on the Prevention and Treatment of Respiratory Diseases in Broilers[J]. China Animal Husbandry and Veterinary Medicine, 2020, 47(3): 940-947.

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Synergistic Effect of Combination of Chinese Veterinary Drugs and Antibiotics on the Prevention and Treatment of Respiratory Diseases in Broilers

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