China Animal Husbandry and Veterinary Medicine ›› 2020, Vol. 47 ›› Issue (3): 948-957.doi: 10.16431/j.cnki.1671-7236.2020.03.035

• Basic Veterinary Medicine • Previous Articles     Next Articles

Advances on Risk Assessment of Tetracycline Antibiotics in the Environment

XU Xiangyue1,2, MA Wenjin1,2, AN Boyu1,2, CHENG Guyue1,2, HUANG Lingli1,2   

  1. 1. MOA Laboratory for Risk Assessment of Quality and Safety of Livestock and Poultry Products(HZAU), Wuhan 430070, China;
    2. National Reference Laboratory of Veterinary Drug Residues(HZAU) and MOA Key Laboratory for Detection of Veterinary Drug Residues, Wuhan 430070, China
  • Received:2019-10-08 Online:2020-03-20 Published:2020-03-17

Abstract: Tetracycline antibiotics (TCs) are the most widely used in veterinary medicine,which is due to factors such as their low cost,broad spectrum and high antimicrobial activity.Due to their poor absorption when administered to animals,most of the doses of TCs are excreted as original (not metabolized) compounds in feces and urine.In this study,exposure status,adsorption and degradation behavior and effect assessment of TCs were reviewed.The results showed that TCs were exposed to a large amount in the environment,with strong adsorption capacity and weak migration capacity.Microorganisms,light and temperature affected their stability.The exposure in the environment had a negative impact on plant,aquatic organisms,microbial community structure and quantity and resistance genes.By summarizing the current situation of environmental risk assessment of TCs,people should pay more attention to the pollution of TCs in the environment,which will provide reference for the removal of TCs and resistance genes in the environment.Consequently,it is urgent to carry out a systematic research on environmental risk assessment of TCs.

Key words: tetracycline antibiotics; environment; adsorption; degradation; ecological toxicity

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