›› 2016, Vol. 43 ›› Issue (1): 197-203.doi: 10.16431/j.cnki.1671-7236.2016.01.029

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Research Progress on Long Non-coding RNA in Growth Regulation of Livestock

SU Xiao-na, XIE Qing-mei, CHEN Feng   

  1. College of Animal Science, South China Agricultural University, Guangzhou 510642, China
  • Received:2015-06-08 Online:2016-01-20 Published:2016-01-23

Abstract: Long non-coding RNA(lncRNA) are non-protein coding transcripts longer than 200 nucleotides that are usually considered collectively as a heterogeneous class of RNA.Recently, an increasing number of studies have shown that lncRNA have a pivotal role in various critical biological processes and a number of complex human diseases.lncRNA act as regulators at different levels of gene expression including chromatin organization, transcriptional regulation, and post-transcriptional control.lncRNA expression disorder has been found to be associated to cancer and other human disease.As functional molecules, lncRNA have attracted more and more researchers attention.Compared to human medicine, it is still at the initial stage of lncRNA application in livestock studies.In the present study, the characteristics, classification, acting mechanisms, methods for lncRNA analysis, as well as research progress in growth regulation of livestock of lncRNA are reviewed, and prospect the application of lncRNA in livestock breeding, in order to provide the theory foundation for thorough study of lncRNA in growth regulation of livestock.

Key words: long non-coding RNA(lncRNA); gene regulation; acting mechanism; livestock; research progress

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