卵黄抗体提取方法及其在畜禽细菌性肠道疾病防治中的应用

doi:10.16431/j.cnki.1671-7236.2021.02.026

Abstract

Abstract: Bacterial intestinal infections are common diseases during breeding process in livestock and poultry industry,which can easily cause problems such as decline in livestock feeding and production performance,and even death.Antibiotics are usually used to breeding process.However,due to the long-term existence of antibiotic abuse and unreasonable use,drug residues and bacterial resistance problems have become increasingly prominent.Therefore,the development of safe and reliable antibiotic alternatives has become a research hotspot in the livestock industry.Egg yolk immunoglobulin (IgY) is immunoglobulin expressed in egg yolk after vaccination of laying hens,it can be used to the prevention and treatment of corresponding diseases.IgY has many advantages such as large output,stable properties,safety and efficiency.Currently,IgY is widely used in livestock and poultry breeding,and has achieved significant advantages.The article reviewed the molecular structure,physicochemical properties and mechanism of IgY.It summarized and compared the fat removal rate,antibody titer,total protein content and other indicators of five kinds of IgY extraction methods.Finally,the research status and application prospects of IgY in the prevention and treatment of common bacterial infections in livestock and poultry were introduced in detail and it was expected to provide research basis and technical support for the efficient production and disease prevention of IgY.

Key words: egg yolk immunoglobulins (IgY); physical and chemical properties; extraction method; bacterial intestinal diseases of livestock and poultry; antibiotic substitutes

CLC Number:

S852.4

HE Weizhao, ZHANG Huiyan, WANG Hao, ZHAO Qingyu, TANG Chaohua, ZHANG Junmin. Extraction Methods of Yolk Antibody and Its Application in Prevention and Treatment of Bacterial Intestinal Diseases in Livestock and Poultry[J]. China Animal Husbandry and Veterinary Medicine, 2021, 48(2): 640-649.

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Extraction Methods of Yolk Antibody and Its Application in Prevention and Treatment of Bacterial Intestinal Diseases in Livestock and Poultry

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