cGhrelin对岭南黄蛋鸡生产性能的影响

摘要/Abstract

摘要： 本研究旨在观察cGhrelin对岭南黄蛋鸡生产性能的调节作用。选择45周龄的岭南黄蛋鸡24羽,随机分为试验组和对照组。试验组定时每3 d翅下静脉注射0.5 nmol/100 g cGhrelin,对照组注射相应体积的生理盐水,并记录各组生产性能;第15天屠宰取样检测生理生化指标。结果表明,cGhrelin可以显著降低蛋鸡的产蛋率及日均采食量(P<0.05),对料蛋比与平均蛋重无显著影响(P>0.05);试验组蛋鸡血清中雌二醇含量显著低于对照组 (P<0.05),且三碘甲腺原氨酸与甲状腺激素含量也明显降低(P>0.05)。因此,cGhrelin对岭南黄蛋鸡部分生产性能有负调控作用。

关键词: cGhrelin; 岭南黄蛋鸡; 生产性能; 甲状腺素; 雌二醇

Abstract: The current study was conducted to investigate the regulatory effects of cGhrelin on productive performance in Lingnan yellow laying hens. A total of 24 Lingnan yellow layers at 45 weeks age were randomly divided into the test group and the control group. The layers in test group were treated by wing intravenous injection of 0.5 nmol/100 g cGhrelin every 3 days, and the layers in control group were injected in the same volume of normal saline as test group. The productive performance of layers was measured every 3 days, and physiological and biochemical indicators were checked on the 15 days through a slaughtering experiment. The results showed that compared with the control, cGrelin could decrease egg production percentage and daily feed intake (P<0.05); but had no significant effects on feed/egg ratio and average egg weight (P>0.05); concentrations of triiodothyronine and thyroxine were decreased obviously (P>0.05) and the level of estradiol was decreased significantly (P<0.05). It indicated that cGhrelin had averse effects on some productive performance in Lingnan yellow layers.

Key words: cGhrelin; Lingnan yellow layers; productive performance; thyroxine; estradiol

中图分类号:

S831.1

董小英, 唐胜球. cGhrelin对岭南黄蛋鸡生产性能的影响[J]. , 2012, 39(7): 116-119.

DONG Xiao-ying, TANG Sheng-qiu. Effects of cGhrelin on Productive Performance in Lingnan Yellow Layers[J]. China Animal Husbandry & Veterinary Medicine, 2012, 39(7): 116-119.

参考文献

1 唐胜球, 董小英. cGhrelin对黄羽肉鸡体重与腹脂率的影响[J]. 西南农业学报, 2010, 23(1):227~230.
2 Caminos J E, Tena-Sempere M, Gaytan F, et al. Expression of ghrelin in the cyclic and pregnant rat ovary. Endocrinology, 2003,144(4):1594~1602.
3 Dafopoulos K, Chalvatzas N, Kosmas G, et al. The effect of estrogens on plasma ghrelin concentrations in women. J Endocrinol Invest, 2010, 33(2):109~112.
4 Furuse M T, Tachibana A, Ohgushi R, et al. Intracerebroventricular injection of ghrelin and growth hormone releasing factor inhibits food intake in neonatal chicks. Neurosci Lett, 2001, 301(2):123~126.
5 Furuta M, Funabashi T, Kimura F. Intracerebroventricular administration of ghrelin rapidly suppresses pulsatile luteinizing hormone secretion in ovariectomized rats. Biochem Biophys Res Commun, 2001, 288(4):780~785.
6 García M C, López M, Alvarez C V, et al. Role of ghrelin in reproduction. Reproduction, 2007, 133(3):531~540.
7 Gaytan F, Barreiro M L, Caminos J E, et al. Expression of ghrelin and its functional receptor, the type 1a growth hormone secretagogue receptor, in normal human testis and testicular tumors. Clin Endocrinol Metab, 2004, 89(1): 400~409.
8 Gnanapavan S, Kola B, Bustin S A, et al. The tissue distribution of the mRNA of ghrelin and subtypes of its receptor, GHS-R, in humans. J Clin Endocrinol Metab, 2002,87(6):2988~2991.
9 Hashizume T, Horiuchi M, Tatea N, et al. Effects of ghrelin on growth hormone secretion from cultured adenohypophysial cells in pigs. Domest Anim Endocrinol, 2003, 24: 209~218.
10 Khazali H. Effect of third ventricle infusuion of ghrelin on plasma GH, T₃, T₄, milk amount and constituents in the dairy goats. Endocrine Abstracts, 2005, 10:48.
11 Kluge M, Riedl1 S, Uhr M, et al. Ghrelin affects the hypothalamus-pituitary-thyroid axis in humans by increasing free thyroxine and decreasing TSH in plasma. European Journal of Endocrinology, 2010, 162(6):1059~1065.
12 Kluge M, Schussler P, Uhr M, et al. Ghrelin suppresses secretion of luteinizing hormone(LH)in humans. Clin Endocrinol Metab, 2007,92(8):3202~3205.
13 Kluge M, Uhr M, Bleninger P, et al. Ghrelin suppresses secretion of follicle stimulating hormone (FSH) in males. Clin Endocrinol (Oxf), 2009, 70(6):920~923.
14 Kojima M, Hosoda H, Date Y, et al. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature,1999, 23(402):656~660.
15 OBrien M, Earley P, Morrison J J, et al. Ghrelin in the human myometrium. Reprod Biol Endocrinol, 2010,8(1):55~65.
16 Saito E, Kaiya H, Takagi T, et al. Chicken ghrelin and growth hormone-releasing peptide-2 inhibit feed intake of neonatal chicks. Eur J Pharmacol, 2002,453(1):75~79.
17 Sirotkin A V, Grossmann R, María-Peon M T, et al. Novel expression and functional role of ghrelin in chicken ovary. Mol Cell Endocrinol, 2006, 257~258:15~25.
18 Sirotkin A V, Grossmann R. The role of ghrelin and some intracellular mechanisms in controlling the secretory activity of chicken ovarian cells. Comp Biochem Physiol A Mol Integr Physiol, 2007,147(1):239~246.
19 Soares J B, Leite-Moreira A F. GhreLin, des-acyl ghrelin and and obestatin: three pieces of the same puzzle. Peptides, 2008, 29(7):1255~1270.
20 Theodoropoulou A, Psyrogiannis A, Metallinos I C, et al. Ghrelin response to oral glucose load in hyperthyroidism, before and after treatment with antithyroid drugs. J Endocrinol Invest, 2009,32(2):94~97.
21 Vulliemoz N R, Xiao E, Xia Z L. Decrease in luteinizing hormone pulse frequency during a five-hour peripheral Ghrelin infusion in the ovariectomized rhesus monkey. Clin Endocrinol Metab, 2004, 89(11):5718~5723.

[1]	王贝贝, 郝二英, 张海华, 张海军, 邱凯, 武书庚. 饲粮中添加有机锰铁铜锌复合制剂对蛋鸡生产性能、血液生化指标、卵巢功能和胫骨质量的影响[J]. 中国畜牧兽医, 2025, 52(5): 2012-2022.
[2]	孙玉丽, 焦宁, 曲扬华, 仉磊, 张晓琳. 黑水虻幼虫的饲用价值以及在养猪生产中的应用进展[J]. 中国畜牧兽医, 2025, 52(5): 2066-2077.
[3]	刘朝乐门, 敖日格乐, 王纯洁, 斯木吉德, 陈浩. 全棉籽在反刍动物生产中的应用研究现状[J]. 中国畜牧兽医, 2025, 52(4): 1651-1659.
[4]	董理月, 范作堃, 唐美慧, 汤建强, 于海亮, 张涛, 张跟喜, 谢恺舟, 赵振华, 戴国俊. 柔嫩艾美耳球虫感染对黄羽肉鸡生产性能、免疫器官和肠道形态的影响[J]. 中国畜牧兽医, 2025, 52(3): 1263-1271.
[5]	郭琪琪, 魏立民, 薛琛璐, 吴蔚, 欧阳坤, 刘宇航, 孙瑞萍, 刘圈炜. 木薯粉对文昌鸡生产性能、血清生化及免疫指标的影响[J]. 中国畜牧兽医, 2025, 52(2): 615-623.
[6]	郭佳佳, 聂晶, 曲久, 旦增占都, 李小伟, 江明锋, 刘益丽. 抗菌肽抑菌作用机制及在畜禽中的应用[J]. 中国畜牧兽医, 2025, 52(2): 934-945.
[7]	王静, 宋丽荣, 刘蓁, 付睿, 王孜, 臧长江, 李凤鸣. 饲粮蛋白质水平对哺育期塔里木鸽种鸽生产性能、消化代谢和血浆生化指标的影响[J]. 中国畜牧兽医, 2024, 51(8): 3301-3310.
[8]	邱凯, 常心雨, 高珊, 张海华, 张海军, 武书庚. 饲粮添加甲酸钙对老龄蛋鸡生产性能和鸡蛋品质的影响[J]. 中国畜牧兽医, 2024, 51(8): 3320-3328.
[9]	马小雪, 龙锐, 牛玉杰, 郭红勇, 罗瑞卿, 吴妍妍, 张文举. 围产期饲粮中添加异位酸对奶牛瘤胃发酵参数、瘤胃微生物和生产性能的影响[J]. 中国畜牧兽医, 2024, 51(4): 1428-1437.
[10]	张腾龙, 郭晨阳, 钟华晨, 刘嘉琳, 宋洁, 王丽芳. 蒲公英和连翘提取物对隐性乳房炎奶牛生产性能、血清抗氧化及免疫指标的影响[J]. 中国畜牧兽医, 2024, 51(4): 1490-1499.
[11]	张文翔, 王建平. 过氧化氢酶对肉鸡生产性能、抗氧化能力、盲肠微生物及代谢物的影响[J]. 中国畜牧兽医, 2024, 51(3): 1086-1093.
[12]	产燕子, 王馨悦, 李思菡, 王俊凯, 王宇艳, 胡铁生, 莫桂芬, 梁德宏, 石达友. 复方中药对强制换羽蛋鸡生产性能及生殖功能的影响[J]. 中国畜牧兽医, 2024, 51(3): 1151-1159.
[13]	黄静, 赵娜, 郭万正, 金枫, 陈芳, 朱伟, 樊启文, 杜恩存, 陶文静, 黄少文, 魏金涛. 饲料桑对蛋鸡生产性能、蛋品质及肠道组织形态的影响[J]. 中国畜牧兽医, 2024, 51(2): 540-548.
[14]	孙鹏飞, 王晓涵, 胡云, 吴慧光, 赵静雯, 罗绪刚. 热应激对鸡生产性能、血清生化和肠道微生物影响研究进展[J]. 中国畜牧兽医, 2024, 51(2): 581-590.
[15]	马忠, 李云雷, 李冬立, 常卓, 杨宇泽, 陈超, 孙研研, 郭艳丽, 陈继兰. 不同光源类型对北京油鸡生长性能、屠宰性能和性发育的影响[J]. 中国畜牧兽医, 2024, 51(12): 5225-5233.