›› 2011, Vol. 38 ›› Issue (8): 167-170.

• 疾病防治 • 上一篇    下一篇

肥大细胞在动物肠道黏膜免疫屏障中的作用

姜楠, 胡易, 陈耀星, 王子旭, 曹静, 董玉兰, 白鹤   

  1. 中国农业大学动物医学院,北京 100193
  • 收稿日期:2011-03-07 修回日期:1900-01-01 出版日期:2011-08-20 发布日期:2011-08-20
  • 通讯作者: 王子旭

Effect of Mast Cell on the Animal Intestinal Mucosal Immune Barrier

JIANG Nan, HU Yi, CHEN Yao-xing, WANG Zi-xu, CAO Jing, DONG Yu-lan, BAI He   

  1. College of Veterinary Medicine,China Agricultural University,Beijing 100193,China
  • Received:2011-03-07 Revised:1900-01-01 Online:2011-08-20 Published:2011-08-20

摘要: 肠道黏膜屏障包括机械屏障和免疫屏障等,后者主要由肠黏膜吸收上皮细胞和肠道相关淋巴组织构成。肠道黏膜免疫细胞包括淋巴细胞、杯状细胞、肥大细胞等。其中肥大细胞是天然免疫的效应细胞之一,其不仅在天然免疫中发挥重要作用,且能通过所分泌的细胞因子参与获得性免疫。笔者综述了肥大细胞的生物学特性及其在肠道免疫屏障中的作用。

关键词: 肥大细胞; 黏膜免疫; 肠道屏障

Abstract: Intestinal mucosal barrier include mechanical barrier and immune barrier etc. The immune barrier mainly is composed of intestinal epithelial absorbed cells and gut-associated lymphoid tissue. Intestinal mucosal immune cells can be included by lymphocytes,goblet cells,mast cell and so on. And mast cell is one of the innate immune effector cells. It can not only play a key role in the innate immunity but also play an important role in the acquired immune by secreting of cytokine. Here we make a brief summary about biological characteristics of mast cell,and its function in intestinal immunological barrier.

Key words: mast cell; mucosal immune; intestinal barrier

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