›› 2014, Vol. 41 ›› Issue (10): 266-269.

• 疾病防治 • 上一篇    下一篇

鸡传染性支气管炎LDT3-A株冻干苗对蛋种鸡的免疫效果观察

张丹俊, 戴银, 赵瑞宏, 胡晓苗, 潘孝成, 刘伟, 沈学怀, 宋霞   

  1. 安徽省农科院畜牧兽医研究所, 安徽合肥 230031
  • 修回日期:2014-07-10 出版日期:2014-10-20 发布日期:2014-10-29
  • 作者简介:张丹俊(1962-),男,安徽人,学士,副研究员,研究方向:畜禽传染病。
  • 基金资助:
    国家现代农业产业技术体系项目(CARS-41);安徽省家禽产业技术体系专项;安徽省农科院科技创新团队项目(11C0404)

Observation of Immunogenic Effect on Egg Breeders Inoculated with Infectious Bronchitis LDT3-A Strains Freeze-dried Vaccine

ZHANG Dan-jun, DAI Yin, ZHAO Rui-hong, HU Xiao-miao, PAN Xiao-cheng, LIU Wei, SHEN Xue-huai, SONG Xia   

  1. Institute of Animal Husbandry and Veterinary Science, Anhui Academy of Agricultural Sciences, Hefei 230031, China
  • Revised:2014-07-10 Online:2014-10-20 Published:2014-10-29

摘要: 本试验旨在对中国自主研发的LDT3-A株鸡传染性支气管炎冻干苗(简称LDT3-A株传支冻干苗)在蛋种鸡中的应用效果进行观察比较。试验组和对照组初免分别使用LDT3-A株传支冻干苗和Ma5+clone30二联冻干苗免疫,在初免后均按照鸡场原定的免疫程序实施其他传支活毒疫苗(如H120、H52)和灭活疫苗免疫,初免后2组所用疫苗完全一致。试验结果显示,LDT3-A株传支冻干苗在父母代蛋种鸡3日龄时1.2倍量滴鼻免疫,免疫后应激反应较小;2组在随后实施相同的其他传支活毒疫苗和灭活疫苗加强免疫的基础上,试验组鸡群得到了有效保护,而对照组鸡群发生了传染性支气管炎疫情。试验期内试验组鸡群总死亡率较对照组降低10.11%;151~210日龄段的平均产蛋率提高了7.0%,种蛋合格率、受精率、出雏率和健雏率分别提高3.0%、2.3%、0.7%和3.2%,料蛋比降低了0.1。研究结果为蛋种鸡场优化筛选鸡传染性支气管炎免疫用疫苗和免疫程序,以及提高其免疫预防效果提供了临床依据。

关键词: LDT3-A株; 鸡传染性支气管炎; 冻干苗; 蛋种鸡; 免疫效果

Abstract: To observe and compare application effects on egg breeders inoculated with infectious bronchitis LDT3-A freeze-dried vaccine,a China's own developed vaccine strain. Test group immunization with LDT3-A strain freeze-dried vaccine and control group immunization with Ma5+clone30 strain bivalent freeze-dried vaccine in first immunization;after the first immunization,flocks immunization other infectious bronchitis live virus vaccine and inactivated vaccine(e.g. H120,H52) according to the immunization program,and vaccination was identical between the two groups. The results showed that more slightly stress response in three-day age egg breeders intranasal vaccinated with LDT3-A strain freeze-dried vaccine at 1.2 times amount;after subsequent supplementary immunization,the test groups had been effectively protected,while the control group occurred infectious bronchitis in flocks. Compared with control group,total mortality reduced 10.11%,151 to 210 days age average egg production rate increased by 7.0%,the eggs pass rate,fertilization rate,hatching rate and healthy chicks rate increased by 3.0%,2.3%,0.7% and 3.2%,respectively,and feed-egg ratio decreased 0.1 in test group. These results provided clinical evidence for selecting infectious bronchitis vaccine and optimal immunization programs in egg breeder farms.

Key words: LDT3-A strain; infectious bronchitis; freeze-dried vaccine; egg breeders; immunogenic effect

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