›› 2011, Vol. 38 ›› Issue (1): 108-111.

• 生物技术 • 上一篇    下一篇

代谢组学及其在动物营养研究中的应用

聂存喜,张文举   

  1. (石河子大学动物科技学院,新疆石河子 832003)
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2011-01-01 发布日期:2011-01-01
  • 通讯作者: 张文举

Metabonomics and its Application in Animal Nutrition

NIE Cun-xi, ZHANG Wen-ju   

  1. (College of Animal Science and Technology,Shihezi University, Shihezi 832003,China)
  • Received:1900-01-01 Revised:1900-01-01 Online:2011-01-01 Published:2011-01-01
  • Contact: ZHANG Wen-ju

摘要: 代谢组学作为一种高通量、高灵敏度、高精确度的现代分析技术,在过去的十几年里得到了迅速的发展,被广泛应用于植物学、微生物、食品学、营养学、毒理学、药物学和环境科学等领域的研究中。随着动物营养学的研究向宏观扩展和微观的深入,代谢组学作为一种强大的技术手段为其提供了重要的技术支持,它将会成为动物营养学研究的重要手段之一。作者从代谢组学的提出、代谢组学的特点及其研究方法对代谢组学进行了简单介绍;并从在研究营养素与机体的相互关系中的应用、用于饲料营养对动物机体影响的评价、用于研究动物消化道菌群与宿主的相互作用、在动物性食品安全中的应用及代谢组学在发酵饲料开发中的应用5个方面综述了代谢组学在动物营养研究中的应用。

关键词: 代谢组学; 动物营养; 色谱联用技术

Abstract:

As a high flux, sensitivity, highly accurate analysis of modern technology ,metabonomics has made Enormous progress over past decade ,which has been used widely in the different fields of science research such as botany, microbiology, bromatology, dietetics, toxicology, pharmacology and environmental science .With the further research on the macroscopic and microcosmic nutritional of animals, metabonomics, as a strong technical means will become an important way of nutritional research. This article give a brief introduction about metabonomics from its generation, characteristic and research methods. Five aspects applications of metabonomics are reviewed in the animal nutritional study :the relationship between nutrient and organism; the interacting research with the host and microbe in the animal enteron ;the foodstuffs from animal related to security; fermentation feed developing.

Key words: metabonomics; animal nutrition; hyphenated techniques chromatography

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