肌细胞生成素基因多态性与泸宁鸡生长性状的关联研究

doi:10.11843/j.issn.1671-7236.2015.03.019

Abstract

Abstract: This study was designed to investigate the correlation between SNP of MyoG gene and growth traits in Luning chicken.The 5'polymorphism of MyoG gene were detected by PCR-SSCP and DNA sequencing technology.As a result,four SNPs (A153G,A267G,A446G and C612T) were found in MyoG gene.Analysis showed that the mutation in 153 bp of MyoG gene exhibited three genotypes (AA,AG and GG),individuals with AA genotype had significant effect on liver weight than those with AG and GG genotypes (P <0.05).The mutation in 446 bp of MyoG gene performed three genotypes (AA,AG and GG),compared with individuals with GG genotype,those with AA and AG genotypes had significant effect on slaughter percentage (P <0.05),and with AA Genotype,those with AG and GG genotypes had significant effect on breast muscle percentage (P <0.05).It could be stated that MyoG gene showed a significant effect on Luning chicken growth traits.So MyoG gene could be served as a candidate gene in growth traits of Luning chicken for further study.

Key words: Luning chicken; MyoG gene; PCR-SSCP; growth traits; association analysis

CLC Number:

S813.3

LIU Hong-li, XU Ya-ou, XIONG Bin, HU Wei-min, MEI Han, SHI Hao, ZUO Bin, NIE Xiao-qing, WANG Hai. Study on the Correlation between Polymorphisms of MyoG Gene and Growth Traits in Luning Chicken[J]. , 2015, 42(3): 629-637.

References

[1] Wright W E,Sassoon D A,Lin V K.Myogenin,a factor regulating myogenesis,has a domain homologous to MyoD[J].Cell,1989,56(4):607-617.

[2] Rawls A,Valdez M R,Zhang W,et al.Overlapping functions of the myogenic bHLH genesMRF4 andMyoD revealed in double mutant mice[J].Development,1998,125(13):2349-2358.

[3] Te Pas M F,Soumillion A,Harders F L,et al.Influences of myogenin genotypes on birth weight,growth rate,carcass weight,backfat thickness,and lean weight of pigs[J].J Anim Sci,1999,77(9):2352-2356.

[4] Braun T,Bober E,Buschhausen-Denker G,et al.Differential expression of myogenic determination genes in muscle cells:Possible autoactivation by the Myf gene products[J].EMBO J,1989,8(12):3617-3625.

[5] Olson E N.MyoD family:A paradigm for development[J].Genes Dev,1990,4(9):1454-1461.

[6] Weintraub H,Davis R,Tapscott S,et al.The MyoD gene family:Nodal point during specification of the muscle cell lineage[J].Science,1991,251(4995):761-766.

[7] Hasty P,Bradley A,Morris J H,et al.Muscle deficiency and neonatal death in mice with a targeted mutation in the myogenin gene[J].Nature,1993,364(6437):501-506.

[8] Nabeshima Y,Hanaoka K,Hayasaka M,et al.Myogenin gene disruption results in perinatal lethality because of severe muscle defect[J].Nature,1993,364(6437):532-535.

[9] Dwyer C M,Fletcher J M,Stickland N C.Muscle cellularity and postnatal growth in the pig[J].J Anim Sci,1993,71(12):3339-3343.

[10] 王琼,刘益平,蒋小松,等.MyoG基因多态性与优质肉鸡屠宰性状和肉质性状的相关性分析[J].遗传,2007,29(9):1089-1096.

[11] Anton I,Zsolnai A,Komlosi I.Effect of MyoG genotypes on growth rate and production traits in Hungarian Large White pigs[J].Acta Vet Hung,2006,54(3):393-397.

[12] 杨宁.现代养鸡生产[M].北京:北京农业大学出版社,1994.

[13] 宋兴超,杨福合,邢秀梅,等.甘肃马鹿基因5'UTR单核苷酸多态性检测及其序列变异分析[J].中国畜牧兽医,2010,37(9):100-106.

[14] 蔡兆伟,罗玉衡,张金枝,等.猪MyoG基因的多态性及其对岔路黑猪胴体和肉质的影响研究[J].家畜生态学报,2008,29(3):11-14.

[15] 郭云雁,陈来华,程笃学,等.MyoG和c-fos基因多态性及其合并基因型与猪肌纤维性状的关联分析[J].畜牧兽医学报,2013,44(2):188-196.

[16] 唐莹,王金玉,张跟喜,等.MyoG基因外显子1多态性与京海黄鸡生长性状的相关性分析[J].中国畜牧杂志,2013,23:5-8.

[17] 唐修君,高玉时,陆俊贤,等.MyoG和A-FABP基因多态性与鹅肉品质性状的相关性研究[J].家畜生态学报,2011,32(6):16-20.

Study on the Correlation between Polymorphisms of MyoG Gene and Growth Traits in Luning Chicken

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