猪3号染色体上与产仔性状和窝内仔猪初生重整齐度显著关联的标记鉴定

doi:10.16431/j.cnki.1671-7236.2020.11.016

Abstract

Abstract: This study was aimed to find the molecular markers significantly associated with litter size traits and uniformity of the piglet's birth weight,and provided a basis for genetic improvement of reproductive traits in pigs.This study was based on the genome-wide selective sweep analysis of pig conducted by the research group in the previous studies,two SNPs (rs338309012 and rs335824784) on porcine chromosome 3 were selected,and the genotyping-in-thousand by sequencing was used,the relationship between two SNPs and litter size traits (including total number born,total number born alive,number of stillborn pigs and number of mummified pigs,etc.) and the uniformity of the piglet's birth weight was association analyzed in Danish Yorkshire and American Yorkshire pigs.The results showed that rs338309012 were significantly associated with the total number born and the number of mummified pigs (P<0.05),and the total number born and the number of mummified pigs of AC genotype sows was significantly higher than CC genotype (P<0.05).rs335824784 was significantly associated with the effective number of born alive and the number of mummified pigs (P<0.05),and was also extremely significantly associated with the total number born alive and the number of stillborn pigs (P<0.01).The effect of different genotypes on the total number born alive and effective number of born alive were GG > CG > CC.On the contrary,the effect of different genotypes on the coefficient of variation of the birth weight of piglets,the number of dead and mummified fetuses were GG < CG < CC.Thus,the GG genotype sows with rs335824784 not only had more total number born alive,but also had regular piglet's birth weight and lower number of stillborn and mummified pigs,which could be used as a molecular marker to improve the litter size traits and uniformity of the piglet's birth weight.

Key words: pigs; reproductive traits; SNP; association analysis

CLC Number:

S813.3

WANG Weiwei, XIAO Yujing, MA Yunlong, LIU Xiangdong, LI Xinyun, YU Mei. Identification of Markers Significantly Associated with Litter Size Traits and Uniformity of the Piglet's Birth Weight on Porcine Chromosome 3[J]. China Animal Husbandry and Veterinary Medicine, 2020, 47(11): 3546-3554.

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Identification of Markers Significantly Associated with Litter Size Traits and Uniformity of the Piglet's Birth Weight on Porcine Chromosome 3

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