›› 2011, Vol. 38 ›› Issue (9): 197-199.

• 兽医临床 • 上一篇    下一篇

产后骨关节炎患牛血液生化指标的研究

王海霞1, 王洪海2, 王国卿3, 王文有4, 张乃生1   

  1. 1. 吉林大学畜牧兽医学院,吉林长春 130062;2. 黑龙江省大庆市畜牧兽医水产局,黑龙江大庆 163311;3. 东北大学生物技术研究所,辽宁沈阳 110004;4. 哈尔滨市宏有牧业责任有限公司,黑龙江哈尔滨 150030
  • 收稿日期:1900-01-01 修回日期:2011-03-21 出版日期:2011-09-20 发布日期:2011-09-20
  • 通讯作者: 王国卿

The Study of Hematological Biochemistry in Osteoarthritis Dairy Cow

WANG Hai-xia1, WANG Hong-hai2, WANG Guo-qing3, WANG Wen-you4, ZHANG Nai-sheng1   

  1. 1. College of Animal Science and Veterinary Medicine, Jilin University, Changchun 130062, China;2. Pasturage Vet Bureau of Daqing City in Heilongjiang Province, Daqing 163311, China;3. Research Institute of Biotechnology, Northeastern University, Shenyang 110004, China;4. Harbin Hongyou Animal Husbandry Limited Liability Company, Harbin 150030, China
  • Received:1900-01-01 Revised:2011-03-21 Online:2011-09-20 Published:2011-09-20

摘要: 通过对产后15~20 d、跗关节炎患牛与正常奶牛血清中蛋白、甲状腺素(T3、T4)、维生素、葡萄糖、乳酸、丙酮酸、Ca、P等生化指标的比较,探讨血液生化指标的变化与奶牛骨关节疾病的关系。结果表明,试验组血清白蛋白显著低于对照组(P<0.05),而α-球蛋白显著高于对照组(P<0.05);试验组T3水平显著高于对照组(P<0.05),T4显著低于对照组(P<0.05);试验组乳酸和丙酮酸水平显著高于对照组(P<0.05);试验组血糖、VA、VC、VE及Ca、P含量均显著低于对照组(P<0.05),说明产后关节炎过程中T4、VA、VC的含量降低使关节软骨的胶原及蛋白多糖合成减少,解聚相对增多,引起血清蛋白组成发生变化;而产后血糖水平降低,引起乳酸、丙酮酸含量升高,低血糖又抑制了VC的合成;关节炎过程中可见Ca、P水平降低,可能是通过影响骨质代谢而促进了关节炎的发生。

关键词: 奶牛; 骨关节炎; 血液生化

Abstract: This article contrasted albumin, thyroxine (T3, T4), vitamin, glucose, lactic acid, pyruvic acid, Ca and P in the blood serum of the arthritis puerperium dairy cow, to study that the relation blood biochemical indicator’s changes with Joint disease. The result indicated the albumin, T4, vitamin A, vitamin C, vitamin E, Ca and P were in experimental group notablely lower than control group, globulin-α, lactic acid, pyruvic acid and T3 were significant higher than control group. It showed that the content of T4 and vitamin were degraded in arthritis postpartum dairy cow maked the collagen in articular cartilage and proteoglycan reduce,depolymerization increase,to cause the compose of serum protein change; but blood sugar level depressed that it caused lactic acid and pyruvic acid raise, hypoglycemia inhibited composition of vitamin C, Ca and P level depressed. It maybe effect sclerotin metabolism to promote development of arthritis.

Key words: dairy cow; osteoarthritis; hematological biochemistry

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