›› 2012, Vol. 39 ›› Issue (4): 162-165.

• 遗传繁育 • 上一篇    下一篇

瘦素对动物生殖调控的研究进展

夏敏, 田科雄   

  1. 湖南农业大学动物营养研究所,饲料安全与高效利用教育部工程研究中心,湖南长沙 410128
  • 收稿日期:2011-09-15 修回日期:1900-01-01 出版日期:2012-04-20 发布日期:2012-04-20
  • 通讯作者: 田科雄

Modulation of Leptin on Animal Reproduction Research

XIA Min, TIAN Ke-xiong   

  1. Engineering Research Center for Feed Safety and Efficient Utilization of Ministry of Education, Institute of Aniamal Nutrition, Hunan Agricultural University, Changsha 410128,China
  • Received:2011-09-15 Revised:1900-01-01 Online:2012-04-20 Published:2012-04-20

摘要: 瘦素是由白色脂肪细胞分泌的一种蛋白类激素,对动物的采食量及能量平衡调控具有明显的作用。除此之外,瘦素对生殖系统也有着重要的调节作用。瘦素通过JAK-STAT途径及与KiSS-1/GPR54系统的相互作用,对动物初情期的启动,下丘脑—垂体—性腺(HPG)轴及胎盘与子宫等产生广泛的影响。

关键词: 瘦素; 生殖; 下丘脑—垂体—性腺轴; KiSS-1/GPR54系统

Abstract: Leptin is a protein hormone secreted from white fat cells,the amount of animal feed and energy balance regulation has a significant role.In addition,a growing number of studies have shown that leptin on the reproductive system also has an important role in the regulation.By going through the JAK-STAT pathway and having interaction with KiSS-1/GPR54 system,leptin have a wide-ranging impact on the animals start puberty,the hypothalamus-pituitary-gonadal (HPG) axis,the placenta and uterus.

Key words: leptin; reproduction; hypothalamus-pituitary-gonadal axis; KiSS-1/GPR54 system

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