microRNA与动物肌肉发育研究进展

摘要/Abstract

摘要： microRNAs(miRNAs)是一类19～25 nt的小分子非编码RNA，通过与靶基因3′-UTR互补配对介导靶基因转录后调控，在生物的生命过程中扮演着十分重要的角色。miRNA作为机体重要的调控子，参与动物生长、发育、疾病等过程。目前，对miRNA的研究已经成为生命科学领域中的热点。作者综述了miRNA对肌肉的发育调控及动物发育miRNA鉴定的最新研究进展。

关键词: 动物; microRNA; 肌肉; 发育

Abstract: microRNAs (miRNAs) are a class of short (19 to 25 nt) non-coding RNAs that negatively regulate gene expression at the post-transcriptional level by binding with 3′-UTR of the target gene. microRNAs play the important roles in the fundamental biological processes. microRNAs involved in the regulation of growth, development and diseases of animal as the key regulators. Up to now, microRNAs have been the focus of studies on life science. In this study, we overview the latest research progress on microRNAs of regulation of muscle development, also introduce the identification and characterization of animal miRNAs.

Key words: animal; microRNA; muscle; development

赵倩君，浦亚斌，关伟军，马月辉. microRNA与动物肌肉发育研究进展[J]. 中国畜牧兽医.

ZHAO Qian-jun, PU Ya-bin, GUAN Wei-jun, MA Yue-hui. Research Progress on microRNA and Development of Animal Muscle[J]. .

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