›› 2010, Vol. 37 ›› Issue (7): 132-135.

• 疾病防治 • 上一篇    下一篇

蓝舌病病毒基因产物及其生物学功能

童亮,柴俊,张以芳,肖晶   

  1. (云南农业大学动物科技学院,昆明 650201)
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2010-07-20 发布日期:2010-07-20
  • 通讯作者: 张以芳

The Gene Product of the Bluetongue Virus and its Biological Functio

TONG Liang, CAI Jun, ZHANG Yi-fang, XIAO Jing   

  1. (College of Animal Science and Technology, Yunnan Agricultural University, Kunming 650201, China)
  • Received:1900-01-01 Revised:1900-01-01 Online:2010-07-20 Published:2010-07-20
  • Contact: ZHANG Yi-fang

摘要: 蓝舌病病毒(bluetongue disease virus,BTV)是呼肠孤病毒科环状病毒属的双股RNA病毒,其核酸由3个大片段(L1~L3)、3个中片段(M4~M6)和4个小片段(S7~S10)等10个节段组成,分别编码7种结构多肽(VP1~VP7)和4种非结构多肽(NS1、NS2、NS3a、NS3b)。通过dsRNA基因组进行体外翻译,再根据各基因与所编码蛋白的关系,查明了各基因编码的蛋白质及其分子质量和功能。

关键词: 蓝舌病病毒; 基因结构; 基因产物; 编码蛋白; 生物学功能

Abstract: Bluetongue disease virus, double-stranded RNA, a member of Orbivirus genus within Reoviridae family, consisting of 10 segments of different sizes nucleic acid (L1 to L3, M4 to M6 and S7 to S10) with seven structural proteins(VP1 to VP7)and four non-structural proteins(NS1, NS2, NS3a, NS3b). The functions and sizes of the proteins encoded by the 10 segments nucleic acid, has been determined by the vitro translation of the genome dsRNA and expression and functional characterization.

Key words: bluetongue disease virus; genetic structure; gene product; encoded proteins; biological function

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