硒代蛋氨酸的生物学功能及其在猪生产中的应用

doi:10.16431/j.cnki.1671-7236.2020.09.015

摘要/Abstract

摘要： 硒（Se）是机体必需的微量元素，其生理作用主要表现在抗氧化、免疫和抗肿瘤等方面。机体缺硒会引发骨骼肌变性或坏死、肝坏死和心肌纤维变性等疾病，因此，硒在人和动物营养方面越来越被人们重视。硒代蛋氨酸（Se-Met）作为有机硒的一种，比亚硒酸钠等无机硒具有更高的生物利用率和更低的毒性，是替代无机硒的有效有机硒源。应现阶段动物生产中对硒的需要，作者以Se-Met为研究对象，介绍了Se-Met在动物机体中的吸收代谢机制，并在此基础上与无机硒进行了比较分析，突出了Se-Met作为有机补硒剂的优越性；简述了Se-Met在机体抗氧化、免疫和抗肿瘤方面的功能、作用机制以及在猪生产中的应用效果；并进一步阐释了Se-Met在猪生产中的应用现状，通过对日增重、日采食量和料重比等生长指标，以及猪肉的pH、滴水损失、硒沉积量和肉色等肉品质指标的分析，进一步确定了Se-Met在猪生产中广泛应用的可能性，为今后猪营养中Se-Met等有机硒广泛替代无机硒提供了参考依据和理论基础，并期望为后续研究提供参考。

关键词: 硒代蛋氨酸; 吸收代谢; 生物学功能; 猪生产

Abstract: As an essential nutrient,selenium plays important role in antioxidation,immunity and antitumor.Selenium deficiency in the body can cause diseases such as skeletal muscle degeneration or necrosis,liver necrosis and myocardial fibrosis.Therefore,it has been paid more and more attention in human and animal nutrition.As a kind of organic selenium,selenomethionine (Se-Met) has higher bioavailability and lower toxicity than sodium selenite,and it is an effective organic selenium source to replace inorganic selenium.In response to the current demand for selenium sources in animal production,this article takes Se-Met as the research object,introduces the absorption and metabolism mechanism of Se-Met in the body,and on this basis,makes a comparative analysis with inorganic selenium,highlighting the advantages of Se-Met as an organic selenium supplement.The function and mechanism of Se-Met in the body's antioxidation,immunity and antitumor,and the effect of its application in animal production are briefly described.The application status of Se-Met in pig production is explained,and through the analysis of growth indicators such as daily weight gain,daily feed intake,and feed-to-weight ratio,as well as meat quality indicators such as pH,drip loss,selenium deposition,and meat color of pork,the possibility of Se-Met being widely used in animal production is further determined.This article aims to provide practical reference and theoretical basis for the widespread replacement of inorganic selenium by organic selenium such as Se-Met in animal nutrition in the future,and provide references for subsequent scientific research.

Key words: selenomethionine; absorption and metabolism; biological function; pig production

中图分类号:

S828.9

张少涛, 李敏, 解玉怀, 程振峰, 杨维仁. 硒代蛋氨酸的生物学功能及其在猪生产中的应用[J]. 中国畜牧兽医, 2020, 47(9): 2824-2832.

ZHANG Shaotao, LI Min, XIE Yuhuai, CHENG Zhenfeng, YANG Weiren. The Biological Function of Selenomethionine and Its Application in Pigs Production[J]. China Animal Husbandry and Veterinary Medicine, 2020, 47(9): 2824-2832.

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