片球菌抑菌机制及其在畜禽生产中的应用

doi:10.16431/j.cnki.1671-7236.2020.10.019

中国畜牧兽医 ›› 2020, Vol. 47 ›› Issue (10): 3203-3213.doi: 10.16431/j.cnki.1671-7236.2020.10.019

片球菌抑菌机制及其在畜禽生产中的应用

檀克勤¹, 唐嘉虹², 马现永¹, 邓盾¹

1. 广东省农业科学院动物科学研究所, 畜禽育种国家重点实验室, 农业农村部华南动物营养与饲料重点实验室, 广东省动物育种与营养公共实验室, 广东省禽肉品质质量安全控制与评定工程技术中心, 广州 510640;
2. 暨南大学生物工程学系, 广州 510632

收稿日期:2020-01-16 出版日期:2020-10-20 发布日期:2020-10-17
通讯作者: 邓盾 E-mail:dengdun2008@126.com
作者简介:檀克勤(1993-),男,安徽池州人,硕士,研究方向:微生物与畜禽健康,E-mail:120269608@qq.com
基金资助:
广东省农业科学院院长基金（201807）；广东省畜禽育种与营养研究重点实验室开放运行项目（2017B030314044）；广东省现代农业产业技术体系创新团队项目（2018LM1080）；清远市创新创业科研团队（2018002）；广东省农业科学院人才计划项目（201803）；广东省现代农业产业技术体系创新团队项目（2019KJ115）

Antibacterial Mechanism of Pediococcus and Its Application in Livestock and Poultry Production

TAN Keqin¹, TANG Jiahong², MA Xianyong¹, DENG Dun¹

1. Guangdong Provincial Poultry Meat Quality, Quality Control and Evaluation Engineering Technology Center, Guangdong Provincial Animal Breeding and Nutrition Public Laboratory, South China Key Laboratory of Animal Nutrition and Feed, Ministry of Agriculture and Rural Affairs, State Key Laboratory of Animal Breeding, Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China;
2. Department of Bioengineering, Jinan University, Guangzhou 510632, China

Received:2020-01-16 Online:2020-10-20 Published:2020-10-17

摘要/Abstract

摘要： 寻找抗生素替代品是养殖业面临的一大课题。片球菌（Pediococcus）是饲料添加目录中允许的益生菌之一，它是一种革兰氏阳性乳酸菌。大量研究表明，片球菌在食品、医疗和养殖行业中有着巨大的应用价值，它们在宿主肠道黏膜细胞表面具有的良好的定植能力，减少了其他细菌的黏附。同时，片球菌能够产生包括片球菌素、有机酸和过氧化氢在内的许多抗菌物质，因而在抑制病原菌生长、改善肠道微生物群落结构、刺激宿主免疫、促进养殖动物生产健康并提升动物生长性能等方面表现出良好的益生性能，但是相比较其他益生菌而言其关注程度不高。作者总结了片球菌产生抑菌物质的种类及其抑菌机制，介绍了片球菌的黏附和免疫调控作用方式，以及片球菌在猪和鸡等畜禽养殖动物生产上的应用，旨在为其在动物生产中的合理应用提供理论参考。片球菌具有广谱、稳定的抑菌效果，丰富的益生性能，它们有利于畜禽动物健康生长，预防病原菌感染，减少疾病发生，因此值得加大推广和应用的力度。

关键词: 片球菌; 片球菌素; 抑菌机制; 益生菌; 畜禽养殖

Abstract: Finding antibiotic alternatives is a major issue in the breeding industry.Pediococcus, a kind of Gram-positive lactic acid bacteria,is one of the probiotics allowed in the feed addition catalogue.A large number of studies have shown that Pediococcus has great application value in the food,medical and breeding industries.Their good colonization ability on the surface of the host intestinal mucosal cells reduces the adhesion of other bacteria.Meanwhile,Pediococcus is able to produce many antibacterial substances including pediocin,organic acids and hydrogen peroxide.Therefore,it's showing their good probiotic performance in inhibiting the growth of pathogenic bacteria,improving the intestinal microbial community structure,stimulating the host's immunity,promoting the health of farmed animals,and improving animal growth performance,However,compared with other probiotics,its degree of attention is not high.This article summarizes the types of bacteriostatic substances produced by Pediococcus and their bacteriostatic mechanisms,introduces Pediococcus's adhesion and immune regulation,and the application of Pediococcus in the production of animals such as pigs and chickens.The aim was to provide a theoretical reference for Pediococcus's reasonable application in animal production.The results discussed in this article indicated that Pediococcus had broad-spectrum,stable bacteriostatic effects and rich probiotic properties.It's beneficial to the healthy growth of livestock and poultry,prevents pathogenic bacterial infections,and reduces the incidence of diseases.Therefore,Pediococcus is worth increasing its promotion and application.

Key words: Pediococcus; pediocins; antibacterial mechanisms; probiotics; livestock breeding

中图分类号:

S828.9

檀克勤, 唐嘉虹, 马现永, 邓盾. 片球菌抑菌机制及其在畜禽生产中的应用[J]. 中国畜牧兽医, 2020, 47(10): 3203-3213.

TAN Keqin, TANG Jiahong, MA Xianyong, DENG Dun. Antibacterial Mechanism of Pediococcus and Its Application in Livestock and Poultry Production[J]. China Animal Husbandry and Veterinary Medicine, 2020, 47(10): 3203-3213.

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片球菌抑菌机制及其在畜禽生产中的应用

Antibacterial Mechanism of Pediococcus and Its Application in Livestock and Poultry Production

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