苯唑西林敏感耐甲氧西林金黄色葡萄球菌研究进展

doi:10.16431/j.cnki.1671-7236.2017.08.034

《中国畜牧兽医》 ›› 2017, Vol. 44 ›› Issue (8): 2458-2464.doi: 10.16431/j.cnki.1671-7236.2017.08.034

苯唑西林敏感耐甲氧西林金黄色葡萄球菌研究进展

赵吴静¹, 徐进强^1,2, 武中庸^1,3, 蒲万霞¹

1. 中国农业科学院兰州畜牧与兽药研究所, 农业部兽用药物创制重点实验室, 甘肃省新兽药工程重点实验室, 兰州 730050;
2. 甘肃农业大学动物医学院, 兰州 730070;
3. 西北民族大学生命科学与工程学院, 兰州 730124

收稿日期:2016-12-28 出版日期:2017-08-20 发布日期:2017-08-18
通讯作者: 蒲万霞 E-mail:puwanxia@caas.cn
作者简介:赵吴静(1989-),女,河南郑州人,硕士生,研究方向:兽医病原微生物耐药性,E-mail:634582057@qq.com
基金资助:
中央级公益性科研院所基本科研业务费专项基金项目——奶牛养殖环境中耐药数据库及奶牛乳房炎病原菌种库建设（610322016014）；国家重点研发计划"畜禽重要病原耐药性检测与控制技术研究"（2016YFD0501306）

Research Progress on Oxacillin-susceptible Methicillin-resistant Staphylococcus aureus

ZHAO Wu-jing¹, XU Jin-qiang^1,2, WU Zhong-yong^1,3, PU Wan-xia¹

1. Key Laboratory of New Animal Drug Project, Gansu Province, Key Laboratory of Veterinary Pharmaceutical Development, Ministry of Agriculture, Lanzhou Institute of Husbandry and Pharmaceutical Sciences of CAAS, Lanzhou 730050, China;
2. College of Veterinary Medicine, Gansu Agricultural University, Lanzhou 730070, China;
3. College of Life Science and Engineering, Northwest University for Nationalities, Lanzhou 730124, China

Received:2016-12-28 Online:2017-08-20 Published:2017-08-18

摘要/Abstract

摘要：

金黄色葡萄球菌（Staphylococcus aureus，SA）是革兰氏阳性菌，是目前临床感染常见的一种病原菌，能引起局部化脓性感染、关节炎、心内膜炎、蜂窝织炎、败血症、脓毒血症等全身感染。近些年来，由于抗生素不合理的使用，金黄色葡萄球菌的耐药性日益严重，特别是苯唑西林敏感耐甲氧西林金黄色葡萄球菌（oxacillin-susceptible methicillin-resistant Staphylococcus aureus，OS-MRSA）的出现给临床治疗增加了巨大的难度。了解OS-MRSA的流行病学特点和耐药机制可帮助临床医师更好地选择治疗药物，鉴于此，作者针对OS-MRSA的流行病学及耐药机制研究进展进行综述。

关键词: 苯唑西林敏感耐甲氧西林金黄色葡萄球菌; 流行病学; 耐药机制

Abstract:

Staphylococcus aureus (S.aureus) is a gram-positive bacteria which could cause many kinds of infections, such as arthritis, endocarditis cellulitis, septicemia, pyemia and other systemic infections. In recent years, due to the unreasonable use of antibiotics, resistant Staphylococcus aureus increased rapidly.Particularly, the oxacillin-susceptible methicillin-resistant Staphylococcus aureus (OS-MRSA),it is a great challenge for clinical treatment. Understand the epidemiological characteristics and the mechanism of drug resistance of OS-MRSA can help clinicians to choose therapeutic drugs much better. This review summarized the research progress of epidemiology and resistant mechanism of OS-MRSA.

Key words: oxacillin-susceptible methicillin-resistant Staphylococcus aureus(OS-MRSA); epidemiology; resistant mechanism

中图分类号:

R446.5

赵吴静, 徐进强, 武中庸, 蒲万霞. 苯唑西林敏感耐甲氧西林金黄色葡萄球菌研究进展[J]. 《中国畜牧兽医》, 2017, 44(8): 2458-2464.

ZHAO Wu-jing, XU Jin-qiang, WU Zhong-yong, PU Wan-xia. Research Progress on Oxacillin-susceptible Methicillin-resistant Staphylococcus aureus[J]. , 2017, 44(8): 2458-2464.

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苯唑西林敏感耐甲氧西林金黄色葡萄球菌研究进展

Research Progress on Oxacillin-susceptible Methicillin-resistant Staphylococcus aureus

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