非编码RNA调节羊绒细度候选基因的研究进展

doi:10.16431/j.cnki.1671-7236.2018.11.024

Abstract

Abstract:

Cashmere fineness is the key quantitative trait to evaluate cashmere quality and cashmere price.In recent years,with the intensive study of cashmere fineness functional marker genes and through the genome-wide association analysis,the candidate genes of fineness traits of cashmere were gradually screened out.But the key regulated genes,their expression levels and molecular regulation mechanisms of cashmere fineness have not been resolved.Gene expression is regulated by a variety of regulatory factors.The regulation of non-coding RNA is more active,it mainly includes microRNA,lncRNA and circRNA.High throughput sequencing and biological information analysis discovered that non-coding RNA is differential expressed and regulated of related target genes of skin,secondary hair follicle and the development of secondary hair follicle in periodic growth in different cashmere fineness of individual in cashmere goat breeds and varieties.At present,the related researchs of using SNP marker,transcriptional screening,high throughput analytical non-coding RNA and genome-wide association analysis to selected differential genes of cashmere fineness have found that the same cashmere fineness target genes focus on two pathways were more,but it was very rare to cover two or more passages.In this paper,the authors mainly discussed the research progress on molecular regulation mechanism of cashmere fineness candidate genes,and microRNA,lncRNA and circRNA on cashmere fineness related target genes at transcriptional level.

Key words: cashmere fineness; target gene; microRNA; lncRNA; circRNA

CLC Number:

S813.2

ZHENG Yuanyuan, HUI Taiyu, GUO Dan, GUO Suling, WANG Yiru, LIU Yuhao, WANG Zicheng, WANG Yingxuan, HUANG Lifei, BAI Wenlin, WANG Zeying. Research Progress on Cashmere Fineness Candidate Genes Regulating by Non-coding RNA[J]. , 2018, 45(11): 3176-3184.

References

[1] 田文亮.中国山羊绒品质分析(一)[J].中国纤检,2015,1:27-31. TIAN W L.Quality analysis of Chinese cashmere(1)[J].China Fiber Inspection,2015,1:27-31.(in Chinese)
[2] 田文亮.中国山羊绒品质分析(二)[J].中国纤检,2015,3:22-25. TIAN W L.Quality analysis of Chinese cashmere(2)[J].China Fiber Inspection,2015,3:22-25.(in Chinese)
[3] 刘海英,杨桂芹,张微,等.FGF5基因对内蒙古绒山羊绒毛性状的影响[J].遗传,2009,31(2):175-179. LIU H Y,YANG G Q,ZHANG W,et al.Effect of FGF5 gene on fibre traits on Inner Mongolia cashmere goats[J].Hereditas,2009,31(2):175-179.(in Chinese)
[4] JIN M,WANG L,LI S,et al.Characterization and expression analysis of KAP7.1,KAP8.2 gene in Liaoning new-breeding cashmere goat hair follicle[J].Molecular Biology Reports,2011,38(5):3023-3028.
[5] ZHAO M,CHEN H,WANG X,et al.A PCR-SSCP and DNA sequencing detecting two silent SNPs at KAP8.1 gene in the cashmere goat[J].Molecular Biology Reports,2009,36(6):1387-1391.
[6] ZENG X C,CHEN H Y,JIA B,et al.Identification of SNPs within the sheep PROP1 gene and their effects on wool traits[J].Molecular Biology Reports,2011,38(4):2723-2728.
[7] ZHOU J P,ZHU X P,ZHANG W,et al.A novel single-nucleotide polymorphism in the 5'upstream region of the prolactin receptor gene is associated with fiber traits in Liaoning cashmere goats[J].Genetics and Molecular Research,2011,10(4):2511-2516.
[8] 刘斌.绒山羊绒毛生长相关基因的筛选、鉴定和多态性分析[D].呼和浩特:内蒙古农业大学,2012. LIU B.Selection,identification and SNP analysis of correlation genes with cashmere growth on cashmere goats[D].Hohhot:Inner Mongolia Agricultural University,2012.(in Chinese)
[9] 狄冉.中国产绒山羊微卫星和单核苷酸多态性研究[D].北京:中国农业科学院,2008. DI R.The microsatellite and SNPs study of Chinese cashmere goats[D].Beijing:Chinese Academy of Agricultural Sciences,2008.(in Chinese)
[10] 李丽娟,张利平,刘武军.三个绒山羊品种KIFI基因多态性与绒用性状相关性研究[D].兰州:甘肃农业大学,2009. LI L J,ZHANG L P,LIU W J.Polymorphism of KIFI gene associated with cashmere traits in there cashmere goat breeds[D].Lanzhou:Gansu Agricultural University,2009.(in Chinese)
[11] 田月珍.中国美利奴羊(新疆型)羊毛细度相关候选基因的筛选及其关联分析[D].乌鲁木齐:新疆农业大学,2012. TIAN Y Z.Study on selection and relation of candidate gene and associated with wool fineness in Merino sheep[D].Urumqi:Xinjiang Agricultural University,2012.(in Chinese)
[12] 于永生,曹阳,朴庆林,等.辽宁绒山羊绒直径相关基因的筛选[J].中国草食动物科学,2014,S1:147-149. YU Y S,CAO Y,PU Q L,et al.Screening of cashmere diameter related genes in Liaoning cashmere goats[J].China Herbivore Science,2014,S1:147-149.(in Chinese)
[13] 张丽丽.MP1基因在辽宁绒山羊皮肤的表达研究[D].大连:辽宁师范大学,2015. ZHANG L L.Study on the expression of MP1 in Liaoning cashmere goat skin[D].Dalian:Liaoning Normal University,2015.(in Chinese)
[14] QIAO X,SU R,WANG Y,et al.Genome-wide target enrichment-aided chip design:A 66 K SNP chip for cashmere goat[J].Scientific Report,2017,7(1):8621.
[15] ZHANG W,GUANG W,JIANG H,et al.A subset of skin-expressed micrornas with possible roles in goat and sheep hair growth based on expression profiling of mammalian micrornas[J].A Journal of Integrative Biology,2007,4(11):385-396.
[16] 樊凯军,尹俊.绒山羊70 d胚胎皮肤小分子RNA文库构建及miRNA鉴定[J].生物技术,2014,24(1):32-36. FAN K J,YIN J.Construction of a small RNA library and identify of miRNAs from 70 days cashmere goat fetal skin[J].Journal of Biology,2014,24(1):32-36.(in Chinese)
[17] LIU Z H,XIAO H M,LI H P,et al.Identification of conserved and novel microRNAs in cashmere goat skin by deep sequencing[J].PLoS One,2012,7(12):e50001.
[18] DONG Y,XIE M,JIANG Y,et al.Sequencing and automated whole-genome optical mapping of the genome of a domestic goat(Capra hircus)[J].Nature Biotechnology,2013,31(2):135-141.
[19] 袁超.绒山羊次级毛囊周期性变化相关microRNA的鉴定及miR-125b在毛乳头细胞中的功能研究[D].杨凌:西北农林科技大学,2014. YUAN C.Identification of micro RNAs in secondary hair follicle cycling and functional analysis of miR-125b in dermal papilla cells of cashmere goats[D].Yangling:Northwest A & F University,2014.(in Chinese)
[20] 付绍印.绒山羊绒毛周期性相关microRNA及其靶基因的研究[D].呼和浩特:内蒙古农业大学,2014. FU S Y.The Research of microRNA and targets related to cashmere cycle in cashmere goat[D].Hohhot:Inner Mongolia Agricultural University,2014.(in Chinese)
[21] 刘洋.绒山羊胎儿期毛囊发育相关microRNA的筛选与鉴定[D].呼和浩特:内蒙古农业大学,2016. LIU Y.Screening and identification of hair follicle development related microRNA in cashmere goat[D].Hohhot:Inner Mongolia Agricultural University,2016.(in Chinese)
[22] DINGER M E,AMARAL P P,MERCER T R,et al.Long noncoding RNAs in mouse embryonic stem cell pluripotency and differentiation[J].Genome Research,2008,18:1433-1445.
[23] MAO Y S,ZHANG B,SPECTOR D L.Biogensis and function of nucler bodies[J].Trends Genet,2011,27:295-306.
[24] GUETG C,LIENEMANN P,SIRRI V,et al.The NoRC complex mediates the heterochromatin formation and stability of silent rRNA genes and centromeric repeats[J].The EMBO Journal,2010,29:2135-2146.
[25] 路畅,黄银花.动物长链非编码RNA研究进展[J].遗传,2017,39(11):1054-1065. LU C,HUANG Y H.Progress in long non-coding RNAs in animals[J].Hereditas,2017,39(11):1054-1065.(in Chinese)
[26] ROTHER S,MEISTER G.Small RNAs derived from longer non-coding RNAs[J].Biochimie,2011,93:1905-1915.
[27] 郭杨.羊绒周期性生长特异性lncRNAs的筛选[D].杨凌:西北农林科技大学,2015. GUO Y.Screening of specific long non-coding RNAs regulating periodic growth of cashmere[D].Yangling:Northwest A & F University,2015.(in Chinese)
[28] WANG S,GE W,LUO Z,et al.Integrated analysis of coding genes and non-coding RNAs during hair follicle cycle of cashmere goat(Capra hircus)[J].BMC Genomics,2017,18(1):767.
[29] BAI W L,ZHAO S J,WANG Z Y,et al.lncRNAs in secondary hair follicle of cashmere goat:Identification,expression,and their regulatory network in wnt signaling pathway[J].Animal Biotechnology,2018,29(3):199-211.
[30] ZHOU G,KANG D,MA S,et al.Integrative analysis reveals ncRNA-mediated molecular regulatory network driving secondaryhair follicle regression in cashmere goats[J].BMC Genomics,2018,19(1):222.
[31] SALZMAN J,GAWAD C,WANG P L,et al.Circular RNAs are the predominant transcript isoform from hundreds of human genes in diverse cell types[J].PLoS One,2012,7(2):e30733.
[32] ZHENG Q,BAO C,GUO W,et al.Circular RNA profiling reveals an abundant circHIPK3 that regulates cell growth by sponging multiple miRNAs[J].Nature Communications,2016,7:11215.
[33] PANDA A C,GRAMMATIKAKIS I,KIM K M,et al.Identification of senescence-associated circular RNAs (SAC-RNAs) reveals senescence suppressor CircPVT1[J].Nucleic Acids Research,2017,45(7):4021-4035.
[34] JECK W R,SORRENTINO J A,WANG K,et al.Circular RNAs are abundant,conserved,and associated with ALU repeats[J].RNA,2013,19(2):141-157.
[35] ZHANG X O,WANG H B,ZHANG Y,et al.Complementary sequence-mediated exon circularization[J].Cell,2014,159(1):134-147.
[36] LI Z,HUANG C,BAO C,et al.Exon-intron circular RNAs regulate transcription in the nucleus[J].Nature Structural & Molecular Biology,2015,22(3):256-264.
[37] LU Z,FILONOV G S,NOTO J J,et al.Metazoan tRNA introns generate stable circular RNAs in vivo[J].RNA,2015,21(9):1554-1565.
[38] ENGLERT M,SHEPPARD K,ASLANIAN A,et al.Archaeal 3'phosphate RNA splicing ligase characterization identifies the missing component in tRNA maturation[J].Proceedings of the National Academy of Sciences of the United States of America,2011,108(4):1290-1295.
[39] GAO Y,WANG J,ZHENG Y,et al.Comprehensive identification of internal structure and alternative splicing events in circular RNAs[J].Nature Communications,2016,7:12060.
[40] 杨平,倪超,陈思,等.环状RNA及其在胃癌中作用的研究进展[J].中国细胞生物学学报,2017,39(12):1633-1641. YANG P,NI C,CHEN S,et al.Advances in circular RNAs and their role in gastric cancer[J].Chinese Journal of Cell Biology,2017,39(12):1633-1641.(in Chinese)
[41] YAO T,CHEN Q,FU L,et al.Circular RNAs:Biogenesis,properties,roles and their relationships with liver diseases[J].Hepatol Research,2017,47(6):497-504.
[42] MEMCZAK S,JENS M,ELEFSINIOTI A,et al.Circular RNAs are a large class of animal RNAs with regulatory potency[J].Nature,2013,495(7441):333-338.
[43] CONN S J,PILLMAN K A,TOUBIA J,et al.The RNA binding protein quaking regulates formation of circRNA[J].Cell,2015,160(6):1125-1134.
[44] ASHWAL-FLUSS R,MEYER M,PAMUDURTI N R,et al.circRNA biogenesis competes with pre-mRNA splicing[J].Molecular Cell,2014,56(1):55-66.
[45] TAO H,XIONG Q,ZHANG F,et al.Circular RNA profiling reveals chi_circ_0008219 function as microRNA sponges in pre-ovulatory ovarian follicles of goats (Capra hircus)[J].Genomics,2017,17:30129-30133.
[46] LI C Y,LI X Y,MA Q M,et al.Genome-wide analysis of circular RNAs in prenatal and postnatal pituitary glands of sheep[J].Scientific Report,2017,7(1):16143.
[47] LI C Y,LI X Y,MA Q M,et al.Genome-wide analysis of circular RNAs in prenatal and postnatal muscle of sheep[J].Oncotarget,2017,8(57):97165-97177.

Research Progress on Cashmere Fineness Candidate Genes Regulating by Non-coding RNA

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