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Research Progress on microRNA and Development of Animal Muscle

ZHAO Qian-jun, PU Ya-bin, GUAN Wei-jun, MA Yue-hui   

  1.  (Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China)
  • Received:2013-08-21 Online:2014-02-20 Published:2014-03-27

Abstract: microRNAs (miRNAs) are a class of short (19 to 25 nt) non-coding RNAs that negatively regulate gene expression at the post-transcriptional level by binding with 3′-UTR of the target gene. microRNAs play the important roles in the fundamental biological processes. microRNAs involved in the regulation of growth, development and diseases of animal as the key regulators. Up to now, microRNAs have been the focus of studies on life science. In this study, we overview the latest research progress on microRNAs of regulation of muscle development, also introduce the identification and characterization of animal miRNAs.

Key words: animal; microRNA; muscle; development