China Animal Husbandry and Veterinary Medicine ›› 2025, Vol. 52 ›› Issue (4): 1914-1923.doi: 10.16431/j.cnki.1671-7236.2025.04.043

• Basic Veterinary Medicine • Previous Articles     Next Articles

Research Progress on Pretreatment and Detection of Veterinary Drug Residues in Food of Animal Origin

CHEN Xiuying, LI Aijun, LI Mingyang, ZHANG Caihua, CUI Yanan, ZHOU Lina, GU Shouguo, ZHOU Yancheng   

  1. Tangshan Food and Drug Comprehensive Inspection and Testing Center, Tangshan 063000, China
  • Received:2024-10-12 Published:2025-03-29

Abstract: Veterinary drugs have played an irreplaceable role in preventing livestock and poultry diseases,promoting growth and improving feed conversion rate.However,food safety problems caused by veterinary drug residues are common in recent years,and it is urgent to carry out detection of veterinary drug residues in animal-derived food to ensure food safety.The author summarized the application progress of pretreatment methods (liquid-liquid extraction,solid phase extraction,accelerated solvent extraction,QuEChERS,dispersive solid-phase extraction and magnetic solid-phase extraction),instrument detection techniques ((ultra) high performance liquid chromatography,(ultra) high performance liquid chromatography-mass spectrometry,gas chromatography-mass spectrometry and matrix assisted laser desorption ionization time-of-flight mass spectrometry),and the rapid detection technology (immunological detection technology,biosensor detection technology,surface enhanced Raman spectroscopy and microbial inhibition analysis technology).The advantages and disadvantages of various pretreatment methods and detection technologies were analyzed,and the future development direction was discussed from the perspective of complementary advantages of instrument detection technology and rapid detection technology.In order to achieve rapid,convenient,intelligent and accurate detection of veterinary drug residues,provided strong support for market supervision and escort food safety.

Key words: food of animal origin; veterinary drug residues; pretreatment; detection technology

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