China Animal Husbandry and Veterinary Medicine ›› 2025, Vol. 52 ›› Issue (4): 1914-1923.doi: 10.16431/j.cnki.1671-7236.2025.04.043
• Basic Veterinary Medicine • Previous Articles Next Articles
CHEN Xiuying, LI Aijun, LI Mingyang, ZHANG Caihua, CUI Yanan, ZHOU Lina, GU Shouguo, ZHOU Yancheng
Received:
2024-10-12
Published:
2025-03-29
CLC Number:
CHEN Xiuying, LI Aijun, LI Mingyang, ZHANG Caihua, CUI Yanan, ZHOU Lina, GU Shouguo, ZHOU Yancheng. Research Progress on Pretreatment and Detection of Veterinary Drug Residues in Food of Animal Origin[J]. China Animal Husbandry and Veterinary Medicine, 2025, 52(4): 1914-1923.
[1] 马宁,王杰,裴斐,等.屠宰、预冷和市售阶段猪肉及内脏中兽药残留分析与风险评估[J].食品科学,2020,41(16):314-319.MA N,WANG J,PEI F,et al.Analysis and risk assessment of veterinary drug residues in pork and viscera at slaughtering,precooling and marketing stages[J]. Food Science,2020,41(16):314-319.(in Chinese) [2] 李春颖,王红义,李永春,等.表面增强拉曼光谱技术在动物源性食品兽药残留检测中的应用[J].光谱学与光谱分析,2023,43(6):1667-1675.LI C Y,WANG H Y,LI Y C,et al.Application of surface enhanced Raman spectroscopy in the detection of veterinary drug residues in animal derived food[J].Spectroscopy and Spectral Analysis,2023,43(6):1667-1675.(in Chinese) [3] 陈一资,胡滨.动物性食品中兽药残留的危害及其原因分析[J].食品与生物技术学报,2009,28(2):162-166.CHEN Y Z,HU B.Hazards and causes of veterinary drug residues in animal food[J].Journal of Food Science and Biotechnology,2009,28(2):162-166.(in Chinese) [4] WANG B,XIE K Z,LEE K.Veterinary drug residues in animal-derived foods:Sample preparation and analytical methods[J].Foods,2021,10(3):555. [5] REGAL P,LAMAS A,FENTE C A,et al.Influence and detection of the residues of veterinary formulations in foods[J].Reference Module in Food Science,2020.Doi:10.1016/B978-0-08-100596-5.22926-0. [6] LI J,REN X,DIAO Y,et al.Multiclass analysis of 25 veterinary drugs in milk by ultra-high performance liquid chromatography-tandem mass spectrometry[J].Food Chemistry,2018,257:259-264. [7] SHIN D,KANG H S,JEONG J,et al.Multi-residue determination of veterinary drugs in fishery products using liquid chromatography-tandem mass spectrometry[J].Food Analytical Methods,2018,11(6):1815-1831. [8] WANG J,ZHAO W,GUO W,et al.Simultaneous screening and analysis of 155 veterinary drugs in livestock foods using ultra-high performance liquid chromatography tandem quadrupole linear-ion-trap mass spectrometry[J].Food Chemistry,2022,393:133260. [9] JIA W,CHU X G,CHANG J,et al.High-throughput untargeted screening of veterinary drug residues and metabolites in tilapia using high resolution orbitrap mass spectrometry[J].Analytica Chimica Acta,2017,957:29-39. [10] NINGA E,SAPOZHNIKOVA Y,LEHOTAY S J,et al.High-throughput mega-method for the analysis of pesticides,veterinary drugs,and environmental contaminants by ultra-high-performance liquid chromatography-tandem mass spectrometry and robotic mini-solid-phase extraction cleanup plus low-pressure gas chromatography-tandem mass spectrometry,part 2:Catfish[J].Journal of Agricultural and Food Chemistry,2021,69(4):1169-1174. [11] WANG C F,LI X W,YU F G,et al.Multi-class analysis of veterinary drugs in eggs using dispersive-solid phase extraction and ultra-high performance liquid chromatography-tandem mass spectrometry[J].Food Chemistry,2021,334:127598. [12] BANG Y S,HUANG Y,LIN D Y.QuEChERS sample pre-processing with UPLC-MS/MS:A method for detecting 19 quinolone-based veterinary drugs in goat's milk[J]. Food Chemistry,2022,16(373):131466. [13] LI H,WU J H,BAI J L,et al.Determination of lincomycin in milk using Cu-based metal-organic framework adsorbent and liquid chromatography-tandem mass spectrometry[J]. Molecules,2023,28:5307. [14] WANG B,WANG Y,XIE X,et al.Quantitative analysis of spectinomycin and lincomycin in poultry eggs by accelerated solvent extraction coupled with gas chromatography tandem mass spectrometry[J].Foods,2020,9(5):651. [15] LI X W,CHI Q C,XIA S J,et al.Untargeted multi-residue method for the simultaneous determination of 141 veterinary drugs and their metabolites in pork by high-performance liquid chromatography time-of-flight mass spectrometry[J].Journal of Chromatography A,2020,1634:461671. [16] SHIN D,KIM J,KANG H S.Simultaneous determination of multi-pesticide residues in fish and shrimp using dispersive-solid phase extraction with liquid chromatography-tandem mass spectrometry[J].Food Control,2021,120:107552. [17] WANG C F,LI X W,YU F G,et al.Multi-class analysis of veterinary drugs in eggs using dispersive-solid phase extraction and ultra-high performance liquid chromatography-tandem mass spectrometry[J].Food Chemistry,2021,334:127598. [18] MELEKHIN A O,TOLMACHEVA V V,GONCHAROV N O,et al.Multi-class,multi-residue determination of 132 veterinary drugs in milk by magnetic solid-phase extraction based on magnetic hypercrosslinked polystyrene prior to their determination by high-performance liquid chromatography-tandem mass spectrometry[J].Food Chemistry,2022,387:132866. [19] CHEN M,ZHAO Y,YANG Y T,et al.Development of a magnetic MOF-based M-D-μSPE methodology combined with LC-MS/MS for the determination of fluorotelomer alcohols and its metabolites in animal derived foods[J].Food Chemistry,2021,363:130205. [20] CHEN D M,WU M R,XIE S Y,et al.Determination of tartrazine,lutein,capsanthin,canthaxanthin and β-carotene in animal-derived foods and feeds by HPLC method[J]. Journal of Chromatographic Science,2019,57,(5):462-468. [21] XU H,MI H Y,GUAN M M,et al.Residue analysis of tetracyclines in milk by HPLC coupled with hollow fiber membranes-based dynamic liquid-liquid micro-extraction[J].Food Chemistry,2017,232:198-202. [22] CHOI J M,ZHENG W J,ABD EL-ATY A M,et al.Residue analysis of tebufenozide and indoxacarb in chicken muscle,milk,egg and aquatic animal products using liquid chromatography-tandem mass spectrometry[J].Biomedical Chromatography,2019,33(7):e4522. [23] ZHENG J P,YE C,WANG P,et al.Quantitative analysis of total methenolone in animal source food by liquid chromatography-tandem mass spectrometry[J].Drug Testing and Analysis,2020,13:148-155. [24] MIOSSEC C,MILLE T,LANCELEUR L,et al.Simultaneous determination of 42 pharmaceuticals in seafood samples by solvent extraction coupled to liquid chromatography-tandem mass spectrometry[J].Food Chemistry,2020,32:126765. [25] JIA Q,QIU J,ZHANG L,et al.Multiclass comparative analysis of veterinary drugs,mycotoxins,and pesticides in bovine milk by ultrahigh-performance liquid chromatography-hybrid quadrupole-linear ion trap mass spectrometry[J].Foods,2022,11(3):331. [26] DU L J,YI L,YE L H,et al.Miniaturized solid-phase extraction of macrolide antibiotics in honey and bovine milk using mesoporous MCM-41 silica as sorbent[J].Journal of Chromatography Acta,2018,1537:10-20. [27] CHEN Q,PAN X D,HUANG B F,et al.Quantification of 16β-lactams in chicken muscle by QuEChERS extraction and UPLC-Q-Orbitrap-MS with parallel reaction monitoring[J].Journal of Pharmaceutical and Biomedical Analysis,2017,145:525-530. [28] ABDALLAH H,ARNAUDGUILHEM C,JABER F,et al.Multiresidue analysis of 22 sulfonamides and their metabolites in animal tissues using quick,easy,cheap,effective,rugged,and safe extraction and high resolution mass spectrometry (hybrid linear ion trap-orbitrap)[J].Journal of Chromatography,2014,1355:61-72. [29] KHALED A,BELINATO J R,PAWLISZYN J.Rapid and high-throughput screening of multi-residue pharmaceutical drugs in bovine tissue using solid phase microextraction and direct analysis in real time-tandem mass spectrometry (SPME-DART-MS/MS)[J].Talanta,2020,217:121095. [30] WANG C,CHEN M,HU Q,et al.Non-lethal microsampling and rapid identification of multi-residue veterinary drugs in aquacultured fish by direct analysis in real time coupled with quadrupole-Orbitrap high-resolution mass spectrometry[J].Microchemical Journal,2021,160:105673. [31] HAN C,HU B Z,JIN N,et al.Accelerated solvent extraction-gel permeation chromatography-gas chromatography-tandem mass spectrometry to rapid detection of clotrimazole residue in animal-derived food[J].LWT-Food Science and Technology,2021,144:111248. [32] ZHAO Y F,BOUKHERROUB R,XU G J,et al.Au@BN-enhanced laser desorption/ionization mass spectrometry and imaging for determination of fipronil and its metabolites in food and biological samples[J].Food Chemistry,2023,418:135935. [33] HE M Y,WANGX J,BIAN Y,et al.Modeling the distribution of malachite green in zebrafish using matrix-assisted laser desorption/ionization mass spectrometry imaging[J].Analytical and Bioanalytical Chemistry,2021,413:7021-7030. [34] HE J X,ZHENG Y,CHEN X,et al.Development of an enzyme-linked immunosorbent assay for the detection of mebendazole in chicken and mutton[J].Analytical Methods,2021,13(14):1740-1746. [35] NI T T,PENG D P,WANG Y X,et al.Development of a broad-spectrum monoclonal antibody-based indirect competitive enzyme-linked immunosorbent assay for the multi-residue detection of avermectins in edible animal tissues and milk[J].Food Chemistry,2019,286:234-240. [36] WANG Z L,SUN Y Z,LIANG D M,et al.Highly sensitive chromatographic time-resolved fluoroimmunoassay for rapid onsite detection of streptomycin in milk[J].Journal of Dairy Science,2020,103:8750-8760. [37] JIANG J L,LUO P J,LIANG J X,et al.A highly sensitive and quantitative time resolved fluorescent microspheres lateral flow immunoassay for streptomycin and dihydrostreptomycin in milk,honey,muscle,liver,and kidney[J].Analytica Chimica Acta,2022,1192:339360. [38] YANG Q B,QI Y H,ZHOU J M,et al.Development of a fluorescent immunochromatographic assay based on quantum dots for the detection of fleroxacin[J].RSC Advances,2021,11(36):22005-22013. [39] LUO M X,XING K Y,GUO Z,et al.Sensitive immunoassays based on a monoclonal antibody for detection of marbofloxacin in milk[J].Journal of Dairy Science,2020,103(9):7791-7800. [40] GAUDIN V,HEDOU C,SOUMET C,et al.Evaluation and validation of a multi-residue method based on biochip technology for the simultaneous screening of six families of antibiotics in muscle and aquaculture products[J].Food Additives and Contaminants:Part A,2016,33(3):403-419. [41] YAO Y Y,WANG X Z,DUAN W N,et al.A label-free,versatile and low-background chemiluminescence aptasensing strategy based on gold nanocluster catalysis combined with the separation of magnetic beads[J].Analyst,2018,143(3):709-714. [42] FENG X B,GAN N,ZHANG H,et al.A novel"dual-po-tential "electrochemiluminescence aptasensor array using CdS quantum dots and luminol-gold nanoparticles as labels for simultaneous detection of malachite green and chloramphenicol[J].Biosensors and Bioelectronics,2015,74:587-593. [43] 窦博鑫,张云亮,王艳,等.生物传感器在食品检测领域的应用研究进展[J].食品安全质量检测学报,2022,13(3):845-851.DOU B X,ZHANG Y L,WANG Y,et al.Advances in the application of biosensors in the field of food detection[J].Journal of Food Safety&Quality,2022,13(3):845-851.(in Chinese) [44] HUANG W,ZHANG H Y,LAI G S,et al.Sensitive and rapid aptasensing of chloramphenicol by colorimetric signal transduction with a DNA zyme-functionalized gold nanoprobe[J].Food Chemistry,2019,270:287-292. [45] ZHANG Y,LIU R,HASSAN M M,et al.Fluorescence resonance energy transfer-based aptasensor for sensitive detection of kanamycin in food[J].Spectrochimica Acta Part A:Molecular and Biomolecular Spectroscopy,2021,262:120147. [46] PAN Y,FEI D W,LIU P H,et al.Surface-enhanced Raman scattering-based lateral flow immunoassay for the detection of chloramphenicol antibiotics using Au@Ag nanoparticles[J].Food Analytical Methods,2021,14(12):2642-2650. [47] YAN W J,YANG L P,ZHANG H,et al.Engineered" hot"core-shell nanostructures for patterned detection of chloramphenicol[J].Biosens Bioelectron,2015,78:67-72 [48] FANG Q Q,LI Y Y,MIAO X X,et al.Sensitive detection of antibiotics using aptamer conformation cooperated enzyme-assisted SERS technology[J].Analyst,2019,144(11):3649-3658. [49] CHEN J,HUANG M Z,KONG L L.Flexible Ag/nanocellulose fibers SERS substrate and its applications for in-situ hazardous residues detection on food[J].Applied Surface Science,2020,533:147454. [50] WU Q,PENG D P,LIU Q Y,et al.A novel microbiological method in microtiter plates for screening seven kinds of widely used antibiotics residues in milk,chicken egg and honey[J].Frontiers in Microbiology,2019,10:43. |
[1] | SUN Zhuwen, LIU Zhengqun, ZHU Longbo, LI Ning, LIU Yanrong, LIANG Shiyue, ZHENG Zi, MU Shuqin, YAN Jun, SUN Chao. Process Optimization and Structure Analysis of Calcium Oxide and Sodium Carbonate Pretreatment of Reed Straw [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(9): 3562-3572. |
[2] | SUN Xingya, LI Qiang, WANG Zhanhui, YU Wenbo, SHI Weimin, ZHANG Suxia. Comparative Study on Veterinary Drug Residue Limit Standards for Poultry Meat and Eggs in China, EU and USA [J]. China Animal Husbandry and Veterinary Medicine, 2022, 49(6): 2362-2375. |
[3] | LI Xin, WANG Zhixia, PAN Yuanhu, XIE Shuyu, YUAN Zonghui, HUANG Lingli, QU Wei. Progress Research on Antibacterial Synergist Preparation for Animals [J]. China Animal Husbandry and Veterinary Medicine, 2021, 48(5): 1816-1824. |
[4] | HE Zhaoyuan, LU Yang, CHEN Jinyuan, XIE Kaizhou, ZHANG Genxi, ZHANG Tao, DAI Guojun. Comparative Study of Veterinary Drug Residue Limit Standards for Pig Tissues in China,USA,EU,Japan and CAC [J]. China Animal Husbandry and Veterinary Medicine, 2021, 48(2): 704-716. |
[5] | LUO Runbo, ZHANG Yangdong, ZHENG Nan, WANG Jiaqi. Advances in High-throughput Detection of Veterinary Drug Residues in Milk and Dairy Products [J]. China Animal Husbandry and Veterinary Medicine, 2020, 47(10): 3410-3416. |
[6] | WANG Yuke, OU Yahong, ZHANG Liyun, WANG Yanxin, WANG Xu, PENG Dapeng, WANG Yulian, PAN Yuanhu, XIE Shuyu, CHEN Dongmei, HUANG Lingli, TAO Yanfei. Research Progress on Sample Preparation for Detection of Sulfonamides and Its Metabolites in Animal Food and Environment [J]. China Animal Husbandry and Veterinary Medicine, 2019, 46(10): 3032-3041. |
[7] | HAN Xiao-ya, CHEN Dong-mei, WANG Yu-lian, TAO Yan-fei, DONG Guo-liang, PENG DA-peng, YUAN Zong-hui. Research Progress on Antibodies Rapid Detection Technology for Veterinary Synthetic Antibacterial Agents [J]. , 2017, 44(6): 1869-1876. |
[8] | NI Teng-teng, PENG Da-peng, XIE Shu-yu, CHEN Dong-mei, WANG Yu-lian, PAN Yuan-hu, TAO Yan-fei, YUAN Zong-hui. Research Progress on Rapid Determination Technology of Avermectins in Feeds and Animal Products [J]. , 2016, 43(9): 2344-2351. |
[9] | YANG Yu. Development of Dairy Mastitis Detection Technology and Its Effect on Milk Quality [J]. , 2013, 40(S1): 109-111. |
[10] | REN Yan-ming. Application of Non-destructive Detection Technology in Raw Milk Detection [J]. , 2013, 40(S1): 81-84. |
[11] | HAN Rong-wei, ZHENG Nan, YU Zhong-na, QU Xue-yin, LI Song-li, ZHOU Xue-wei, WANG Jia-qi. Development of Risk Warning Method of Veterinary Drug Residues in Raw Milk Based on Shewhart Control Chart [J]. , 2013, 40(S1): 12-17. |
[12] | QIU Zheng-yan, GUO Jiang, YANG Chun, ZHAO Zhi-hui. Research Progress of DNA Methylation in Animal Genetics and Breeding [J]. , 2012, 39(7): 173-178. |
[13] | JIANG Cheng-yan;LI Kai-ming;XIE Kun;WEI Jing-ping;CHEN Lian. Porcine Circovirus type 2 Advances in Detection Technology [J]. , 2012, 39(1): 188-191. |
[14] | ZHAO Fan-fan;YOU Wei-yun;WANG Xiao-du;GAO Li-rong;YUAN Jin-qiang;WANG Ting;ZHOU Qi. Progress of Detection Technology for the Swine Japanese Encephalitis B [J]. , 2011, 38(10): 174-180. |
[15] | YU Hua;YAN Yu-bao;XIE jing;HU Juan;LIAO Dang-jin;ZHOU Min-jiang;CUI Peng-bo;YE Jian-qiang. Application of Enzyme-linked Immunosorbent Assay in Detection of Veterinary Drug Residues in Product of Animal [J]. , 2010, 37(11): 76-79. |
Viewed | ||||||
Full text |
|
|||||
Abstract |
|
|||||