Abstract: The experiment was conducted to use three dosage levels of ceftiofur suspension (10,5,2.5 mg/kg) with twice in 72 h and ceftiofur sodium injection (10 mg/kg) with twice in one day for 3 days to cure piglet pleuropneumonia by intramuscular injection．The results showed that both ceftiofur suspension of three inclusion levels and ceftiofur sodium injection as medicine control group have significantly therapeutic efficacy on piglet contagiows pleuropneumonia and the survival rate was up to 80% to 100%, which was distinguished higher level than the infection control group(P<0.01)．Especially，the high and the medium level of ceftiofur suspension had higher survival rate than the low levels of ceftiofur suspension and ceftiofur sodium injection(P<0.01)．Artificial infection experiment indicated that ceftiofur suspension could reduce clinical symptom and decrease mortality．The levels of ceftiofur suspension(5 to 10 mg/kg) had better effection as injection on curing Actinobacillus pleuropneumoniae．

Key words: ceftiofur suspension; piglet; contagious pleuropneumonia