复方中药发酵粉对断奶仔猪生长性能、养分表观消化率、抗氧化功能以及免疫功能的影响

doi:10.16431/j.cnki.1671-7236.2022.04.014

Abstract

Abstract: 【Objective】 This experiment was conducted to investigate the effects of compound Chinese medicine fermentation powder on growth performance,nutrient apparent digestibility,antioxidant function and immune function in weaned piglets.【Method】 48 healthy crossbred and castrated weaned piglets (Duroc×Landrace×Yorkshire) of 28-day-old with similar initial body weight of (8.290±0.140) kg were randomly divided into 2 groups with 6 replicates per group and 4 pigs per replicate.Pigs in the control group were fed a basal diet,while the piglets in the experimental group was fed a basal diet containing 3% compound Chinese medicine fermentation powder.The compound Chinese medicine fermentation powder was fermented from Hawthorn,Tangerine peel,chicken’s gizzard-membrane,Chinese yam and Poria cocos,and its main active substances include organic acids,flavonoids,polysaccharides and triterpenoids.The trial lasted for 28 d,3 d before the end of the experiment,dietary and fecal samples were collected.At the end of the experiment,one weaned piglets with an average body weight were selected from each replicate for slaughter,plasma and liver were collected and growth performance,nutrient apparent digestibility,plasma and liver antioxidant indices and plasma immune indices were detected.【Result】 Compared with the control group,there were no significant differences in the average daily feed intake (ADFI) and the feed to gain ratio (F/G) of weaned piglets in the compound Chinese medicine fermentation powder group (P>0.05),but the average daily gain (ADG) was significantly increased (P<0.05),and the diarrhea rate was significantly decreased (P<0.05).Compared with the control group,the apparent digestibility of ether extract (EE) and ash (Ash) and calcium (Ca) in the compound Chinese medicine fermentation powder group were extremely significantly or significantly increased (P<0.01;P<0.05).Compared with the control group,the plasma catalase (CAT) and glutathione peroxidase (GSH-Px) activities and the total antioxidant capacity (T-AOC) of weaned piglets in compound Chinese medicine fermentation powder group were significantly or extremely significantly increased (P<0.05;P<0.01).Furthermore,the activity of total superoxide dismutase (T-SOD) in liver of piglets in the compound Chinese medicine fermentation powder group was significantly higher than that of control group (P<0.05).Compared with the control group,the content of immunoglobulin A (IgA) and immunoglobulin M (IgM) in plasma of piglets in the compound Chinese medicine fermentation powder group were significantly increased (P<0.05),while the content of tumor necrosis factor-α (TNF-α) was significantly decreased (P<0.05).【Conclusion】 Adding 3% compound Chinese medicine fermentation powder in the basal diet could improve the apparent digestibility of EE,Ash and Ca,improve the antioxidation capacity and enhance the immune function of the body,thereby reducing diarrhea rate and improving the growth performance of weaned piglets.

Key words: compound Chinese medicine fermentation powder; weaned piglets; nutrient apparent digestibility; antioxidant function; immune fuction

CLC Number:

S828

WANG Chaopu, MA Xianyong, TIAN Zhimei, YU Miao, LIU Zhichang, DENG Dun, RONG Ting, TI Junling, SONG Min, ZHANG Huihua. Effects of Compound Chinese Medicine Fermentation Powder on Growth Performance,Nutrient Apparent Digestibility,Antioxidant Function and Immune Function of Weaned Piglets[J]. China Animal Husbandry and Veterinary Medicine, 2022, 49(4): 1322-1331.

References

[1] HEO J M,OPAPEJU F O,PLUSKE J R,et al.Gastrointestinal health and function in weaned pigs:A review of feeding strategies to control post-weaning diarrhoea without using in-feed antimicrobial compounds[J].Journal of Animal Physiology and Animal Nutrition,2013,97(2):207-237.
[2] BROWN D C,MAXWELL C V,ERF G F,et al.The influence of different management systems and age on intestinal morphology,immune cell numbers and mucin production from goblet cells in post-weaning pigs[J].Veterinary Immunology and Immunopathology,2006,111(3-4):187-198.
[3] LI Y,GUO Y,WEN Z S,et al.Weaning stress perturbs gut microbiome and its metabolic profile in piglets[J].Scientific Reports,2018,8(177):159-169.
[4] 徐子伟.仔猪肠道损伤修复营养调控及其机制和应用[J].动物营养学报,2014,26(10):3033-3045. XU Z W.Mechanism and application for nutritional regulations of intestine damage repair in piglets[J].Chinese Journal of Animal Nutrition,2014,26(10):3033-3045.(in Chinese)
[5] YANG K M,JIANG Z Y,ZHENG C T,et al.Effect of Lactobacillus plantarum on diarrhea and intestinal barrier function of young piglets challenged with enterotoxigenic Escherichia coli K88[J].Journal of Animal Science,2014,92(4):1496-1503.
[6] 高铎,孙鹏.中草药添加剂在畜禽养殖中的应用潜力及挑战[J].家畜生态学报,2021,42(4):7-12. GAO D,SUN P.Application potential and challenges of Chinese herbal medicine additives in livestock and poultry breeding[J].Journal of Domestic Animal Ecology,2021,42(4):7-12.(in Chinese)
[7] LI L,WANG L,FAN W X,et al.The application of fermentation technology in traditional Chinese medicine:A review[J].The American Journal of Chinese Medicine,2020,48(4):899-921.
[8] WANG Y,XIE Q,SUN S,et al.Probiotics-fermented massa medicata fermentata ameliorates weaning stress in piglets related to improving intestinal homeostasis[J].Applied Microbiology and Biotechnology,2018,102(24):10713-10727.
[9] 侯海锋,李茜.发酵中药渣对断奶仔猪生长性能、血液生化指标、抗氧化能力及免疫功能的影响[J].中国畜牧兽医,2018,45(4):947-952. HOU H F,LI Q.Effects of fermented Chinese herb residues on growth performance,serum biochemical parameters,antioxidant indexes and immune function of weaned piglets[J].China Animal Husbandry & Veterinary Medicine,2018,45(4):947-952.(in Chinese)
[10] SU J Y,ZHU Q,ZHAO Y,et al.Dietary supplementation with Chinese herbal residues or their fermented products modifies the colonic microbiota,bacterial metabolites,and expression of genes related to colon barrier function in weaned piglets[J].Frontiers in Microbiology,2018,9:3181.
[11] 余苗,李贞明,陈卫东,等.黑水虻幼虫粉对育肥猪营养物质消化率、血清生化指标和氨基酸组成的影响[J].动物营养学报,2019,31(7):3330-3337. YU M,LI Z M,CHEN W D,et al.Effects of hermetia illucens L.larvae meal on nutrient digestibility,serum biochemical indices and amino acid composition of finishing pigs[J].Chinese Journal of Animal Nutrition,2019,31(7):3330-3337.(in Chinese)
[12] 谢全喜,亓秀晔,陈振,等.复合微生态制剂对断奶仔猪生长性能、腹泻率、免疫性能和肠道菌群的影响[J].动物营养学报,2017,29(3):850-858. XIE Q X,QI X Y,CHEN Z,et al.Effects of compound probiotics on growth performance,diarrhea rate,immunity performance and intestinal microflora of weaned piglets[J].Chinese Journal of Animal Nutrition,2017,29(3):850-858.(in Chinese)
[13] HUANG C W,LEE T T,SHIH Y C,et al.Effects of dietary supplementation of Chinese medicinal herbs on polymorphonuclear neutrophil immune activity and small intestinal morphology in weanling pigs[J].Journal of Animal Physiology and Animal Nutrition,2012,96(2):285-294.
[14] 武洪志,宋玉卓,王志龙,等.发酵复方中草药对断奶仔猪生长性能、免疫和生化指标的影响[J].东北农业大学学报,2017,48(8):15-24. WU H Z,SONG Y Z,WANG Z L,et al.Effect of fermented compound Chinese herbal medicine on growth,performance,immune and biochemical indices of weaned piglets[J].Journal of Northeast Agricultural University,2017,48(8):15-24.(in Chinese)
[15] 曲浩杰,赵旭,杨在宾,等.中药复方发酵粉对断奶仔猪生长性能、养分表观消化率和消化酶活性的影响[J].中国畜牧兽医,2019,46(12):3563-3571. QU H J,ZHAO X,YANG Z B,et al.Effets of Chinese herbal compound fermentation powder on growth performance,nutrient apparent digestibility and digestive enzyme activities of weaned piglets[J].China Animal Husbandry & Veterinary Medicine,2019,46(12):3563-3571.(in Chinese)
[16] 董延江,陈稼,韩庆军,等.发酵中草药(本草酵素)对断奶仔猪生长性能、免疫力和抗氧化能力的影响[J].饲料研究,2020,43(11):37-39. DONG Y J,CHEN J,HAN Q J,et al.Effect of fermented Chinese herbal medicine(Bencaojiaosu)on growth performance,immunity and antioxidant capacity of weaned piglets[J].Feed Research,2020,43(11):37-39.(in Chinese)
[17] 董嘉琪,陈金鹏,龚苏晓,等.山楂的化学成分、药理作用及质量标志物(Q-Marker)预测[J].中草药,2021,52(9):2801-2818. DONG J Q,CHEN J P,GONG S X,et al.Research progress on chemical constituents and pharmacological effectsof Crataegi Fructus and predictive analysis on Q-Marker[J].Chinese Traditional and Herbal Drugs,2021,52(9):2801-2818.(in Chinese)
[18] 赵秀玲.陈皮生理活性成分研究进展[J].食品工业科技,2013,34(12):376-381. ZHAO X L.Research progress in physiologically active compounds of Pericarpium citri reticulatae[J].Science and Technology of Food Industry,2013,34(12):376-381.(in Chinese)
[19] 王宝庆,郭宇莲,练有扬,等.鸡内金化学成分及药理作用研究进展[J].安徽农业科学,2017,45(33):137-139. WANG B Q,GUO Y L,LIAN Y Y,et al.Advances in chemical constituents and pharmacological effects of endothelium corneum gigeriage galli[J].Journal of Anhui Agricultural Sciences,2017,45(33):137-139.(in Chinese)
[20] 张飞,李越,毕丁仁,等.益生菌对仔猪作用机制研究进展[J].家畜生态学报,2021,42(1):7-14. ZHANG F,LI Y,BI D R,et al.Advances on regulation mechanism of probiotics on piglets[J].Journal of Domestic Animal Ecology,2021,42(1):7-14.(in Chinese)
[21] ZHAO P Y,LI H L,LEI Y,et al.Effect of fermented medicinal plants on growth performance,nutrient digestibility,fecal noxious gas emissions,and diarrhea score in weanling pigs[J].Journal of the Science of Food and Agriculture,2016,96(4):1269-1274.
[22] LEI X J,YUN H M,KIM I H.Effects of dietary supplementation of natural and fermented herbs on growth performance,nutrient digestibility,blood parameters,meat quality and fatty acid composition in growing-finishing pigs[J].Italian Journal of Animal Science,2018,17(4):984-993.
[23] SUN Z Y,LI H H,LI Y P,et al.Lactobacillus salivarius,a potential probiotic to improve the health of LPS-challenged piglet intestine by alleviating inflammation as well as oxidative stress in a dose-dependent manner during weaning transition[J].Frontiers in Veterinary Science,2020,7:547425.
[24] GONG J,XIAO M.Effect of organic selenium supplementation on selenium status,oxidative stress and antioxidant status in selenium-adequate dairy cows during the periparturient period[J].Biological Trace Element Research,2018,186(2):430-440.
[25] GONG J,XIAO M.Selenium and antioxidant status in dairy cows at different stages of lactation[J].Biological Trace Element Research,2016,171(1):89-93.
[26] JERRY W S,WILLIAM P W.Role of antioxidants and trace elements in health and immunity of transition dairy cows[J].The Veterinary Journal,2008,176(1):70-76.
[27] 方磊涵,王中华,王留.中药复方发酵剂对断奶仔猪生长性能、血清抗氧化活性及肠道菌群的影响[J].饲料研究,2019,42(8):11-15. FANG L H,WANG Z H,WANG L.Effect of compound Chinese medicine fermentation on growth performance,serum antioxidant activity and intestinal microflora of weaned piglets[J].Feed Research,2019,42(8):11-15.(in Chinese)
[28] 丁鹏,丁亚南,曾青华,等.发酵饲料桑粉对宁乡花猪抗氧化性能和肠道功能的影响[J].动物营养学报,2019,31(9):4303-4313. DING P,DING Y N,ZENG Q H,et al.Effects of fermented forage Mulberry powder on antioxidant,performance and intestinal function of Ningxiang pigs[J].Chinese Journal of Animal Nutrition,2019,31(9):4303-4313.(in Chinese)
[29] 伏春燕,董以雷,阎佩佩,等.饲粮色氨酸水平对肉鸡生长性能、血清生化指标、器官指数及肠道组织形态的影响[J].动物营养学报,2021,33(10):5545-5556. FU C Y,DONG Y L,YAN P P,et al.Effects of dietary tryptophan levels on growth performance,serum biochemical indices,organ indexes and intestinal morphology of broilers[J].Chinese Journal of Animal Nutrition,2021,33(10):5545-5556.(in Chinese)
[30] KARMTEJ S,CHRISTOPHER C,GERSHWIN M E.IgA deficiency and autoimmunity[J].Autoimmunity Reviews,2014,13(2):163-177.
[31] KAPUR R,EINARSDOTTIR H K,VIDARSSON G.IgG-effector functions:"The good,the bad and the ugly"[J].Immunology Letters,2014,160(2):139-144.
[32] KEYT B A,BALIGA R,SINCLAIR A M,et al.Structure,function and therapeutic use of IgM antibodies[J].Antibodies,2020,9(4):53.
[33] PHILIPPE B,DANIEL G.TNF-α disrupts the integrity of the porcine respiratory epithelial barrier[J].Research in Veterinary Science,2019,124:13-17.
[34] 段雪磊,巴翠晶,李得鑫,等.绞股蓝微粉发酵物对断奶仔猪免疫功能的影响[J].中国兽医学报,2016,36(11):1929-1932. DUAN X L,BA C J,LI D X,et al.Effects of the fermented ultrafine powder of Gynostemma on immune function of weaning piglets[J].Chinese Journal of Veterinary Science,2016,36(11):1929-1932.(in Chinese)
[35] 刁新平,王利军,陈美霞,等.发酵白术对断奶仔猪生长性能和血清生化免疫指标的影响[J].东北农业大学学报,2014,45(10):64-73. DIAO X P,WANG L J,CHEN M X,et al.Effect of fermented Atractylodes on growth performance and blood biochemical and immuneindices of weaned piglets[J].Journal of Northeast Agricultural University,2014,45(10):64-73.(in Chinese)
[36] 李敏.山药活性成分提取技术及药理功能的研究进展[J].南方农业学报,2013,44(7):1184-1190. LI M.Overview on extractive techniques and pharmacological functions of active constituents in Rhizoma dioscoreae[J].Journal of Southern Agriculture,2013,44(7):1184-1190.(in Chinese)
[37] 蒋逸凡,金梦圆,周选围.茯苓多糖及其免疫调节功能研究进展[J].食用菌学报,2021,28(2):130-139. JIANG Y F,JIN M Y,ZHOU X W.Research progress on Wolfiporia cocos polysaccharides and their immunoregulatory functions[J].Acta Edulis Fungi,2021,28(2):130-139.(in Chinese)

Effects of Compound Chinese Medicine Fermentation Powder on Growth Performance,Nutrient Apparent Digestibility,Antioxidant Function and Immune Function of Weaned Piglets

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