Abstract: The experiment was aim to evaluate the clinical safety on feeding the different does of flavonoid from Oxytropis glabra DC in diet for mice. 48 mice aged from 6-week-old to 8-week-old were randomly divided into 4 groups,the average body weight of mice was (20±2)g, there were 12 mice in every group, every group had 6 male mice and 6 female mice.The control group was fed complete feed,the experimentⅠ,Ⅱ,Ⅲ groups were fed with the adding of 10,30,50 mg/kg flavonoid from Oxytropis glabra DC.The trial period was 30 d. The results revealed that fed with flavonoid from Oxytropis glabra DC had no any abnormal clinical symptoms.The serum biochemical indicators,hematological indices and organ coefficients exsited in normal limits. It showed that flavonoid from Oxytropis glabra DC in forage had no subchronic toxicity, and was safety for mice.

Key words: Oxytropis glabra DC; flavonoid; subchronic toxicity