高原民族和动物低氧适应血液生理特征及相关基因研究进展

Abstract

Abstract: Plateau environment is characterized by low oxygen partial pressure, plateau nation and animals settled in highlands at different time and levels height, subject to different degrees and different times of hypoxia selection. Physiological characteristic of blood is an important performance of hypoxia adaptation, and blood physiological parameters can directly reflect organism’s adaptability to hypoxic environment. At the same time, genes related hypoxia adaptation play very important roles in the regulation process of body hypoxia adaptation. The researchs on hypoxia adaptation of plateau nation and animals are concentrated in blood physiology and its molecular mechanism, more and more genes that involve in regulation pathways of hypoxia adaptation are found with developing of molecular biology techniques. In this paper, we review the progress of research on blood physiological characteristics and related genes of hypoxia adaptation.

Key words: hypoxia adaptation; blood physiology; candidate gene; plateau nation; plateau animal

CLC Number:

Q494

JIANG Yan-ting, GOU Xiao, LI Ming-li, YAN Da-wei, LI Ji-zhong, LU Shao-xiong. Physiological Characteristics of Blood and Research Progress on Hypoxia Candidate Genes in Plateau Nation and Animals[J]. , 2012, 39(10): 149-153.

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Physiological Characteristics of Blood and Research Progress on Hypoxia Candidate Genes in Plateau Nation and Animals

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