奶牛体内超数排卵反应性状研究进展

doi:10.16431/j.cnki.1671-7236.2023.11.019

Abstract

Abstract: In the modern dairy industry, the multiple ovulation and embryo transfer (MOET) is the key technology, which can significantly accelerate the genetic improvement of dairy population.However, there is a large variation in superovulation response among different donor cows, which is one of the major limitations for the widely applying of superovulation.Therefore, there is an urgent need to explore the causes of variation in superovulation response and to predict the effect of exogenous hormone treatment for donor cows so that suitable donors can be selected.In previous studies, it had been widely reported that the superovulation response trait is heritable in dairy cows, and that genetic selection can substantially improve superovulation efficiency.In general, superovulation response trait is defined as the total number of embryos as well as the number of transferable embryos.Superovulation response trait can be influenced by several factors, including season, donor age, procedure and operator.As a novel reproductive trait with low to medium heritability, it was found to be associated with several genes that regulate the expression of reproductive hormones and cell growth and differentiation.At present, there are relatively few studies on genetics and breeding of superovulation response trait in China, and only a few studies reported candidate genes associated with superovulation response trait.The author systematically reviewed the advance of superovulation response trait in dairy cattle, including the trait definition, modeling of non-genetic factors, estimation of genetic parameters, and identification of candidate genes.In addition, we also discussed the research methods and application of superovulation response trait in the future.

Key words: dairy cow; superovulation; genetic parameter; genetic marker; candidate gene

CLC Number:

S814.4

HUANG Yuechuan, ZHANG Hailiang, ZHAO Shanjiang, LIU Zhanpeng, ZHU Huabin, HUANG Xixia, WANG Yachun. A Review on in vivo Superovulation Response Trait in Dairy Cows[J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(11): 4504-4512.

References

[1] GOMEZ-LEON V E, GINTHER O J, ARAUJO E R, et al.Hormonal mechanisms regulating follicular wave dynamics Ⅰ:Comparison of follicle growth profiles under different physiological conditions in heifers[J].Theriogenology, 2019, 123:194-201.
[2] LAND R B, HILL W G.The possible use of superovulation and embryo transfer in cattle to increase response to selection[J].Animal Science, 1975, 21(1):1-12.
[3] NICHOLAS F W, SMITH C.Increased rates of genetic change in dairy cattle by embryo transfer and splitting[J].Animal Science, 1983, 36(3):341-353.
[4] RUANE J, THOMPSON R.Comparison of simulated and theoretical results in adult MOET nucleus schemes for dairy cattle[J].Livestock Production Science, 1991, 28(1):1-20.
[5] COLLEAU J J.Using embryo sexing within closed mixed multiple ovulation and embryo transfer schemes for selection on dairy cattle[J].Journal of Dairy Science, 1991, 74(11):3973-3984.
[6] HASLER J F.Bovine embryo transfer:Are efficiencies improving?[A].Nashville, TN:Applied Reproductive Strategies Conference Proceedings[C], 2010.
[7] MAPLETOFT R J, BO G A.The evolution of improved and simplified superovulation protocols in cattle[J].Reproduction Fertility & Development, 2011, 24(1):278-283.
[8] 王洋洋, 隋鹤鸣, 赵善江, 等.牛超数排卵技术研究进展[J].生物技术通报, 2019, 35(11):208-216. WANG Y Y, SUI H M, ZHAO S J, et al.Advances in superovulation of the cow[J].Biotechnology Bulletin, 2019, 35(11):208-216.(in Chinese)
[9] JATON C, KOECK A, SARGOLZAEI M, et al.Genetic analysis of superovulatory response of Holstein cows in Canada[J].Journal of Dairy Science, 2016, 99(5):3612-3623.
[10] JATON C, KOECK A, SARGOLZAEI M, et al.Genome-wide association study and in silico functional analysis of the number of embryos produced by Holstein donors[J].Journal of Dairy Science, 2018, 101(8):7248-7257.
[11] PARKER G K L, DIKMEN S, NULL D J, et al.Evaluation of genetic components in traits related to superovulation, in vitro fertilization, and embryo transfer in Holstein cattle[J].Journal of Dairy Science, 2017, 100(4):2877-2891.
[12] KÖNIG S, BOSSELMANN F, BORSTEL V U U, et al.Genetic analysis of traits affecting the success of embryo transfer in dairy cattle[J].Journal of Dairy Science, 2007, 90(8):3945-3954.
[13] KOHRAM H, POORHAMDOLLAH M.Relationships between the ovarian status and superovulatory responses in dairy cattle[J].Animal Reproduction Science, 2012, 131(3):123-128.
[14] 倪兴军, 薛仰全, 余四九.影响奶牛超数排卵效果因素的分析与研究[J].中国牛业科学, 2015, 41(1):42-45. NI X J, XUE Y Q, YU S J.Analysis and study on factors affecting the effect of superovulation in dairy cows[J].China Cattle Science, 2015, 41(1):42-45.(in Chinese)
[15] SCHILLO K K.Effects of dietary energy on control of luteinizing hormone secretion in cattle and sheep[J].Journal of Dairy Science, 1992, 70(4):1271.
[16] 田亚丽, 赵成平.牛超数排卵的方法及其影响因素[J].当代畜牧, 2004, 3:32-33. TIAN Y L, ZHAO C P.Methods and influencing factors of superovulation in cattle[J].Contemporary Animal Husbandry, 2004, 3:32-33.(in Chinese)
[17] 王林, 庞云渭, 郝海生, 等.激素剂量、超排间隔及重复超排次数对和牛重复超排效果的影响[J].中国畜牧兽医, 2021, 48(9):3394-3402. WANG L, PANG Y W, HAO H S, et al.Effects of hormone dosage, superovulation interval and repeated times on repeated superovulation in Wagyu cattle[J]. China Animal Husbandry & Veterinary Medicine, 2021, 48(9):3394-3402.(in Chinese)
[18] LERNER S P, THAYNE W V, BAKER R D, et al.Age, dose of FSH and other factors affecting superovulation in Holstein cows[J].Journal of Dairy Science, 1986, 63(1):176-183.
[19] KAITLIN R K, FERMIN J K, EMILY G, et al.Negative impact of high doses of follicle-stimulating hormone during superovulation on the ovulatory follicle function in small ovarian reserve dairy heifers dagger[J].Biology of Reproduction, 2021, 104(3):695-705.
[20] TONHATI H, LÔBO R B, OLIVEIRA H N.Repeatability and heritability of response to superovulation in Holstein cows[J].Theriogenology, 1999, 51(6):1151-1156.
[21] BENYEI B, GASPARDY A, KOMLOSI I, et al.Repeatability and heritability of ovulation number and embryos in dam-daughters pairs in superovulated Holstein-Friesian cows[J].Reproduction in Domestic Animals, 2004, 39(2):99-102.
[22] ASADA Y, TERAWAKI Y.Heritability and repeatability of superovulatory responses in Holstein population in Hokkaido, Japan[J].Asian-Australasian Journal of Animal Sciences, 2002, 7(15):944-948.
[23] HASLER J F, MCCAULEY A D, SCHERMERHORN E C, et al.Superovulatory responses of Holstein cows[J].Theriogenology, 1983, 19(1):83-99.
[24] BOLAND M P.Gamete and embryo technology:Multiple ovulation and embryo transfer[J].Encyclopedia of Dairy Sciences, 2002, 1:1170-1175.
[25] KADOKAWA H, TAMEOKA N, UCHIZA M, et al.Short communication:A field study on the relationship between body condition and embryo production in superovulated Holstein yearling heifers[J].Journal of Dairy Science, 2008, 91(3):1087-1091.
[26] RUEBEL M L, MARTINS L R, SCHALL P Z, et al.Effects of early lactation body condition loss in dairy cows on serum lipid profiles and on oocyte and cumulus cell transcriptomes[J].Journal of Dairy Science, 2022, 105(10):8470-8484.
[27] ERIKSSON S, HÄGGSTRÖM M, STÅLHAMMAR H.Genetic parameters for superovulatory response in Swedish Red cattle and Swedish Holstein heifers[A].Dublin:EAAP-Session 10 Free Communication on Animal Genetics[C].2007.
[28] TANG K Q, LI S J, YANG W C, et al.An MspI polymorphism in the inhibin alpha gene and its associations with superovulation traits in Chinese Holstein cows[J].Molecular Biology Reports, 2011, 38(1):17-21.
[29] MCDANELD T G, KUEHN L A, THOMAS M G, et al.Genome wide association study of reproductive efficiency in female cattle[J].Journal of Animal Science, 2014, 92(5):1945-1957.
[30] KOLBEHDARI D, WANG Z, GRANT J R, et al.A whole-genome scan to map quantitative trait loci for conformation and functional traits in Canadian Holstein bulls[J].Journal of Dairy Science, 2008, 91(7):2844-2856.
[31] 牛志宏, 冯云.FSH受体基因单核苷酸多态性与卵巢功能[J].中国妇幼健康研究, 2008, 3:268-270. NIU Z H, FENG Y.Single nucleotide polymorphism of FSH receptor gene and ovarian function[J].Chinese Journal of Woman and Child Health Research, 2008, 3:268-270.(in Chinese)
[32] ANDREAS E, ARIFIANTINI I, SAPUTRA F, et al.Effect of FSH β-subunit and FSHR genes polymorphisms on superovulatory response traits[J].Journal of the Indonesian Tropical Animal Agriculture, 2015, 39(4):197-203.
[33] YANG W, LI S, XIE Y, et al.Two novel SNPs of the type Ⅰ gonadotropin releasing hormone receptor gene and their associations with superovulation traits in Chinese Holstein cows[J].Livestock Science, 2011, 136(2):164-168.
[34] YU Y, PANG Y, ZHAO H, et al.Association of a missense mutation in the luteinizing hormone/choriogonadotropin receptor gene (LHCGR) with superovulation traits in Chinese Holstein heifers[J].Journal of Animal Science and Biotechnology, 2012, 3(1):35.
[35] YANG W, LI S, TANG K, et al.Polymorphisms in the 5' upstream region of the FSH receptor gene, and their association with superovulation traits in Chinese Holstein cows[J].Animal Reproduction Science, 2010, 119(3):172-177.
[36] TANG K Q, YANG C W, BIN P, et al.Effects of PGR and ESRα genotypes on the pregnancy rates after embryo transfer in Luxi cattle[J].Molecular Biology Reports, 2013, (40):579-584.
[37] LI C H, XIA P J, MA Y J, et al.Expression pattern of ZNF33B in bovine ovaries and the effect of its polymorphism on superovulation traits[J].Archives Animal Breeding, 2022, 65(1):69-77.
[38] CENGIZ K, OZLEM G K, HOBBS R J, et al.Follicle-stimulating hormone receptor (FSHR) alternative skipping of exon 2 or 3 affects ovarian response to FSH[J].Molecular Human Reproduction, 2014, 20(7):630-643.
[39] 罗布, 朱彦宾, 巴桑旺堆, 等.黑白花牛INHA基因多态性与超数排卵性状关系[J].基因组学与应用生物学, 2019, 38(2):511-515. LUO B, ZHU Y B, BASANG W D, et al.Relationship between INHA gene polymorphism and superovulation traits in black and white cattle[J].Genomics and Applied Biology, 2019, 38(2):511-515.(in Chinese)
[40] WU Y, ZHANG Z, ZHANG J B, et al.Association of growth factor receptor-bound protein 10 gene polymorphism with superovulation traits in Changbaishan Black cattle[J]. Genetic and Molecular Research, 2016, 15(4):1-9.
[41] TANG K Q, YANG W C, LI S J, et al.Polymorphisms of the bovine growth differentiation factor 9 gene associated with superovulation performance in Chinese Holstein cows[J].Genetic and Molecular Research, 2013, 12(1):390-399.
[42] SUGIMOTO M, SASAKI S, GOTOH Y, et al.Genetic variants related to gap junctions and hormone secretion influence conception rates in cows[J]. Proceedings of the National Academy of Sciences of the United States of America, 2013, 110(48):19495-19500.
[43] YANG W C, YANG L G, RIAZ H, et al.Effects in cattle of genetic variation within the IGF1R gene on the superovulation performance and pregnancy rates after embryo transfer[J].Animal Reproduction Science, 2013, 143(1-4):24-29.
[44] MINEGISHI T, HIRAKAWA T, KISHI H, et al.A role of insulin-like growth factor Ⅰ for follicle-stimulating hormone receptor expression in rat granulosa cells[J].Biology of Reproduction, 2000, 62(2):325-333.

A Review on in vivo Superovulation Response Trait in Dairy Cows

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