2013－2019年贵州省副猪嗜血杆菌分离株耐药性及其演变

doi:10.16431/j.cnki.1671-7236.2020.10.034

Abstract

Abstract: This study was aimed to reveal the trend of drug resistance about Haemophilus parasuis (Hps) in Guizhou province and guide clinical use of Glasser's disease then slow the emergence of drug-resistant Hps strains.K-B slip-agar diffusion method was used to test the 15 common antibiotics resistance of 517 Hps strains isolated from 9 districts in Guizhou province from 2013 to 2019.The drug resistance differences of strains isolated from different time and districts were analyzed.The results showed that 14.36% to 70.58% isolates indicated drug resistance to 15 antibiotics,the proportion of EFT resistant strains was the lowest and SXT resistant strains was the highest.Compared with 2013,the resistance rate of Hps strains isolated in 2019 to 13 antibiotics increased by 4.52% to 324.68%.Among them,the proportion of drug-resistant strains of 13 drugs increased which EFT resistant strains increased at the fastest rate to 324.68% while STR resistant strains slowest rate to only 4.52%.The rate of TET resistant strains showed negative growth which decreased by 2.21% and 8.63%,respectively.Compared with Kaili,Bijie and Xingyi of Guizhou,the strains isolated from Anshun,Zunyi and Guiyang districts showed higher drug resistance rate of EFT,MC and DO which with low resistance in Guizhou province,but lower of SXT,AML and STR which with high resistance in Guizhou province.The results indicated that the resistance of Hps strains to 15 commonly antibiotics in Guizhou province was serious with rising tendency and the resistance rate of certain strains showed obvious differences between different districts.

Key words: Guizhou province; Haemophilus parasuis (Hps); drug sensitivity; drug resistance

CLC Number:

S852.61⁺2

SHI Kaizhi, DU Chunlin, WANG Jing, ZHANG Jing, YANG Maosheng, LI Yongming. Drug Resistance and Evolution of Haemophilus parasuis Isolates from Guizhou Province During 2013 to 2019[J]. China Animal Husbandry and Veterinary Medicine, 2020, 47(10): 3343-3350.

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Drug Resistance and Evolution of Haemophilus parasuis Isolates from Guizhou Province During 2013 to 2019

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