嗜水气单胞菌群体感应系统及其抑制剂应用研究进展

doi:10.16431/j.cnki.1671-7236.2023.05.026

Abstract

Abstract: In recent years,with the abuse of antibiotics in aquaculture,bacterial drug resistance has emerged,so green,safe and efficient new strategies are needed to alleviate the drug resistance problem.As a communication mechanism,quorum sensing regulates the behavior and physiological response of bacteria according to the density between cells.Many active substances can affect the pathogenicity of pathogenic bacteria through quorum sensing system without inhibiting the growth of pathogenic bacteria,and at the same time slow down the emergence of drug resistance.Therefore,in recent years,inhibitors that inhibit bacterial quorum sensing system have become a research hotspot.Aeromonas hydrophila,as the main conditional pathogen in aquaculture,seriously harms the economic development of aquaculture.This paper introduced the mechanism of quorum sensing system of Aeromonas hydrophila,the regulation of bacterial biofilm,and the application of quorum sensing system inhibitors of Chinese herbal medicine and probiotics in the prevention and control of Aeromonas hydrophila,aiming at analyzing the development potential of quorum sensing inhibition of Aeromonas hydrophila in the future and providing some reference for the prevention and control of Aeromonas hydrophila in aquaculture.

Key words: Aeromonas hydrophila; quorum sensing; quorum sensing inhibitor; drug resistance

CLC Number:

S852.61

ZENG Chengrong, LIU Xin, BI Wenwen, MEI Shihui, HE Guangxia, ZHANG Junjie, WEN Ming, ZHOU Bijun, CHEN Jiangfeng, JIANG Haibo. Research Progress on Quorum Sensing System of Aeromonas hydrophila and Its Inhibitor Application[J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(5): 1991-2000.

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Research Progress on Quorum Sensing System of Aeromonas hydrophila and Its Inhibitor Application

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