日粮中添加凝结芽孢杆菌对断奶仔猪小肠功能的影响

doi:10.16431/j.cnki.1671-7236.2019.03.004

Abstract

Abstract:

The study was to investigate the effects of Bacillus coagulans (BC) on intestinal function in weaned piglets.Twenty-four piglets were randomly allocated into three groups.The control group was fed the based diet,whereas the BC Ⅰ and BC Ⅱ groups were fed the basal diet supplemented with 2×10⁶ and 2×10⁷ CFU/g Bacillus coagulans,respectively.On the 21th day of the trial,D-xylose (0.1 g/(kg·BW)) was orally administrated to all piglets.One hour later,jugular vein blood samples were collected,and then all pigs were sacrificed to obtain the mid-ileum and the chyme of ileum and colon.The results showed that,cmpared with the control group,plasma diamine oxidase (DAO) activities in BC Ⅰ and BC Ⅱ groups were significantly decreased (P<0.05),and plasma D-xylose content was significantly increased in BC Ⅰ group (P<0.05).The actitivies of ileum glutathione peroxidase (GSH-Px) in BC Ⅰ and BC Ⅱ groups increased significantly (P<0.05),and the content of ileal glutathione (GSH) in BC Ⅱ group increased (P>0.05).The content of ileal malondialdehyde (MDA) was significantly decreased (P<0.05);The mRNA expression of ileal mucosa aquaporin 3 (AQP3),basic amino acid transporter (b^0,+AT) and sodium glucose cotransporter 1 (SGLT-1) in BC Ⅰ group increased significantly (P<0.05).The mRNA expression levels of ileum mucosa AQP3,AQP10,inward rectifier potassium channel 13 (KCNJ13),b^0,+AT,SGLT-1 were significantly increased in BC Ⅱ group (P<0.05).The number of Enterococcus,Bifidobacterium in the ileum and colon of BC Ⅰ group were significantly increased (P<0.05).The number of Enterococcus in the ileum,Enterococcus,Bifidobacterium in colon of BC Ⅱ group were significantly increased (P<0.05).In summary,the addition of Bacillus coagulans in the diet could improve the intestinal absorption,transport capacity and antioxidant capacity of weaned piglets,and improve the intestinal flora structure of weaned piglets.

Key words: Bacillus coagulans; weaned piglets; intestinal function

CLC Number:

S816.7

WU Mengjun, JI Changzheng, LI Siyuan, DONG Yi, ZHAO Guangyu, ZHANG Yue, WANG Lei, ZHAO Di, YI Dan, HOU Yongqing. Effects of Bacillus coagulans on Intestinal Function in Weaned Piglets[J]. , 2019, 46(3): 669-676.

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Effects of Bacillus coagulans on Intestinal Function in Weaned Piglets

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