›› 2016, Vol. 43 ›› Issue (12): 3368-3374.doi: 10.16431/j.cnki.1671-7236.2016.12.042

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Research Progress on Bacterial Resistance in Environment

ZHU Zhen, LI Bing, ZHOU Xu-zheng, WEI Xiao-juan, CHENG Fu-sheng, ZHANG Ji-yu   

  1. Key Laboratory for Veterinary Drug Innovation, Ministry of Agriculture, Lanzhou Institute of Husbandry and Pharmaceutical Science, Chinese Academy of Agricultural Sciences, Lanzhou 730050, China
  • Received:2016-06-25 Online:2016-12-20 Published:2016-12-22

Abstract:

Antibiotic resistance genes have become a recognized environmental pollutant, threatening the ecological safety and human health. The application of antibiotics in the clinical and animals breeding, making the environmental microorganisms living with the impact of the residue of antibiotics and elements of resistance genetic and leading to antibiotic resistant bacteria to gain a competitive advantage and destroyed the stability of ecosystem. In this paper, we expounded the concept of resistance gene transmission by the view of macro environment. Through analyzing the mechanism of resistance development,environmental pollution caused by drug resistance and the impact of environmental microorganism for drug resistance, we clarified the key role of the environment in the development of the characteristics of bacterial resistance and analysis environmental resistance.Such as the ecological diversity of flora, the types and the spread of resistant bacteria, the residues of antibiotics and the transmission of the resistance genes.

Key words: antibiotic; resistance genes; environmental microorganisms

CLC Number: