瘦素与哺乳动物繁殖活动关系的研究进展

doi:10.16431/j.cnki.1671-7236.2015.07.031

Abstract

Abstract: Studies in the last two decades found that Leptin not only involves in the regulation of mammalian ingestion and energy homeostasis,but also serves as a metabolic signal regulating the mammalian reproduction by acting on the hypothalamic-pituitary-gonadal (HPG) axis,the placenta and the uterus.Leptin gene is one of the most important candidate genes for research on livestock's growth,development and meat quality,and also for research on prolificacy of livestock due to its key role in regulating the mammalian embryo implantation.Therefore,it is of important scientific significance and potential application value in studying functions and mechanisms of Leptin and its receptor gene.This paper is to dwell on how Leptin regulates mammalian breeding activities including the onset of puberty,development of reproductive organs and gonads,secretion of reproductive hormones,and embryo implantation,and also on how some reproduction activities influence the Leptin secretion in the body.

Key words: Leptin; reproduction; candidate gene; puberty; reproductive hormones; embryo implantation

CLC Number:

ZHANG Yi. Research Advance on the Relationship between Leptin and Reproduction Activities of Mammal[J]. , 2015, 42(7): 1836-1841.

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Research Advance on the Relationship between Leptin and Reproduction Activities of Mammal

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