[1] 赵若阳,赵一萍,李蓓,等.马毛色遗传机理研究进展[J].遗传,2018,40(5):357-368. ZHAO R Y,ZHAO Y P,LI B,et al.Overview of the genetic control of horse coat color patterns[J].Hereditas,2018,40(5):357-368.(in Chinese) [2] CARO T.The adaptive significance of coloration in mammals[J].BioOne,2005,55(2):125-156. [3] CASTLE W E.Coat color inheritance in horses and in other mammals[J].Genetics,1954,39(1):35-44. [4] SUNDSTRÖM E,IMSLAND F,MIKKO S,et al.Copy number expansion of the STX17 duplication in melanoma tissue from grey horses[J].BMC Genomics,2012,13(365):1-3. [5] 文琴.发育神经学[M].北京:科学出版社,2007. WEN Q.Developmental Neurology[M].Beijing:Science Press,2007.(in Chinese) [6] 王乐,吕雪峰,郑文新,等.动物毛色形成的原因和机制[J].草食家畜,2009,3(1):20-21. WANG L,LYU X F,ZHENG W X,et al.The cause and mechanism of animal coat color formed[J].Grass-feeding Livestock,2009,3(1):20-21.(in Chinese) [7] MORTARJOY K G,ROBBINS L S,MORTRUD M T,et al.The cloning of a family of genes that encode the melanocortin receptors[J].Science,1992,257(5074):1248-1251. [8] 李蓓,何小龙,赵一萍,等.马毛色遗传的分子基础与应[J].遗传,2010,32(11):1133-1140. LI B,HE X L,ZHAO Y P,et al.Molecular basis and applicability in equine color genetics[J].Hereditas,2010,32(11):1133-1140.(in Chinese) [9] 田腾飞.山羊Agouti基因内含子3变异在不同毛色群体中分布研究[D].保定:河北农业大学,2012. TIAN T F.Research about distribution of variations in inron 3 of Agouti gene in different coat color goat[D].Baoding:Hebei Agricultural University,2012.(in Chinese) [10] OLLMANN M M,BARSH G S.Down-regulation of melanocortin receptor signaling mediated by the amino terminus of Agouti protein in Xenopus melanophores[J].Journal of Biological Chemistry,1999,274(22):15837-15846. [11] SUZUKI I,TADA A,OLLMANN M M,et al.Agouti signaling protein inhibits elanogenesis and the response of human melanocytes to α-melanotropin[J].The Journal of Investigative Dermatology,1997,108(6):838-842. [12] NEWTON R A,ROBERTS D W,LEONARD J H,et al.A missense mutation in the gene for melanocyte-stimulating hormone receptor (MC1R) is associated with the chestnut coat color in horses[J].Mammalian Genome,1996,7(12):895-899. [13] RIEDER S,HAGGER C,OBEXER-RUFF G,et al.Genetic analysis of white facial and leg markings in the Swiss Franches-Montagnes horse breed[J].The Journal of Heredity,2008,99(2):130-136. [14] JACOBS L N,STAIGER E A,ALBRIGHT J D,et al.The MC1R and ASIP coat color loci may impact behavior in the horse[J].Journal of Heredity,2016,107(3):214-219. [15] ROUZAUD F,MARTIN J,GALLET P F,et al.A first genotyping assay of French cattle breeds based on a new allele of the extension gene encoding the melanocortin-1 receptor (MC1R)[J].Genetic,Selection,Evolution,2000,32(5):511-520. [16] MAUDET C,TABERLET P.Holstein's milk detection in cheeses inferred from melanocort in receptor 1(MC1R) gene polymorphism[J].Dairy Science,2002,85:707-715. [17] 甘海云,李建斌,王洪梅,等.牛黑素皮质素受1(MC1R)基因与毛色表型的研究[J].遗传,2007,29(2):195-200. GAN H Y,LI J B,WANG H M,et al.Relationship between the melanocortin receptor 1(MC1R) gene and the coat color phenotype in cattle[J].Hereditas,2007,29(2):195-200.(in Chinese) [18] ROYO L J,ALVAREZ I,FERNÁNDEZ I,et al.The coding sequence of the ASIP gene is identical in nine wild-type coloured cattle breeds[J].Journal of Animal Breeding and Genetics,2005,122(5):357-360. [19] MOHANTY T R,SEO K S,PARK K M,et al.Molecular variation in pigmentation genes contributing to coat colour in native Korean Hanwoo cattle[J].Animal Genetics,2008,39(5):550-553. [20] HEPP D,GONÇALVES G L,MOREIRA G R,et al.Identification of the allele at the extension locus (MC1R) in Brazilian Creole sheep and its role in wool color variation[J].Genetic and Molecular Research,2012,11(3):2997-3006. [21] VAGE D I,FLEET M R,PONZ R,et al.Mapping and characterization of the dominant black colour locus in sheep[J].Pigment Cell Research,2003,16(6):693-697. [22] ROYO L J,ALVAREZ I,ARRANZ J J,et al.Differences in the expression of the ASIP gene are involved in the recessive black coat color pattern in sheep:Evidence from the rare Xalda sheep breed[J].Animal Genetics,2008,39(3):290-293. [23] YANG G L,FU D L,LANG X,et al.Mutations in MC1R gene determine black coat color phenotype in Chinese sheep[J].Scientific World Journal,2013,2013:675382-675389. [24] NORRIS B J,WHAN V A.A gene duplication affecting expression of the bovine ASIP gene is responsible for white and black sheep[J].Genome Research,2008,18(8):1282-1293. [25] KIJAS J M,WALES R,TÖRNSTEN A,et al.Melanocotin receptor 1(MC1R) mutation and coat color in pigs[J].Genetics,1998,150:1177-1185. [26] CIOBANU D C,DAY A E,NAGY A,et al.Genetic variation in two conserved local Romanian pig breeds using type 1 DNA markers[J].Genetic Selection Evolution,2001,33(4):417-432. [27] DRÖGEMÜLLER C,GIESE A,MARTINS-WESS F,et al.The mutation causing the black-and-tan pigmentation phenotype of Mangalitza pigs maps to the porcine ASIP locus but does not affect its coding sequence[J].Mammalian Genome,2006,17(1):58-66. [28] SANTSCHI E M,PURDY A K,VALBERG S J,et al.Endothelin receptor B polymorphism associated with lethal white foal syndrome in horses[J].Mammalian Genome,1998,9(4):306-309. [29] MAU C,PONCET P A,BUCHER B,et al.Genetic mapping of dominant white (W),a homozygous lethal condition in the horse (Equus caballus)[J].Journal of Animal Breeding and Genetics,2004,121(6):374-383. [30] HAASE B,BROOKS S A,TOZAKI T,et al.Seven novel KIT mutations in horses with white coat colour phenotypes[J].Animal Genetic,2009,40(5):623-629. [31] HAUSWIRTH R,JUDE R,HAASE B,et al.Novel variants in the KIT and PAX3 genes in horses with white-spotted coat colour phenotypes[J].Animal Genetic,2013,44(6):763-765. [32] BRENIG B,BECK J,FLOREN C,et al.Molecular genetics of coat color variations in White Galloway and White Park cattle[J].Animal Genetics,2013,44(4):450-453. [33] ZHANG M Q,XU X,LUO S J.The genetics of brown coat color and white spotting in domestic yaks (Bos grunniens)[J].Animal Genetics,2014,45(5):652-659. [34] DURKIN K,COPPIETERS W,DROGEMULLER C,et al.Serial translocation by means of circular intermediates underlies colour sidedness in cattle[J].Nature,2012,482(7383):81-86. [35] JOHANSSON M,ELLEGREN H,MARKLUND L,et al.The gene for dominant white color in the pig is closely linked to ALB and PDGRFRA on chromosome 8[J].Genomics,1992,14(4):965-969. [36] JOHANSSON M,CHAUDHARY R,NELLMÉN E,et al.Pigs with the dominant white coat color phenotype carry a duplication of the KIT gene encoding the mast/stem cell growth factor receptor[J].Mammalian Genome,1996,7(11):822-830. [37] GIUFFRA E,EVANS G,TÖRNSTEN A,et al.The belt mutation in pigs is an allele at the dominant white (I/KIT) locus[J].Mammalian Genome,1999,10(12):1132-1136. [38] PIELBERG G,OLSSON C,SYVÄNEN A C,et al.Unexpectedly high allelic diversity at the KIT locus causing dominant white color in the domestic pig[J].Genetics,2002,160(1):305-311. [39] JOHANSSON A,PIELBERG G,ANDERSSON L,et al.Polymorphism at the porcine dominant white/KIT locus influence coat color and peripheral blood cell measures[J].Animal Genetics,2005,36(4):288-296. [40] DIETRICH J,MENZI F,AMMANN P,et al.A breeding experiment confirms the dominant mode of inheritance of the brown coat color associated with the (496) Asp TYRP1 allele in goats[J].Animal Genetics,2015,46(5):587-588. [41] 杨舒黎,毛华明,舒文,等.云南乌骨绵羊乌质性状与TYR基因多态性的相关分析[J].遗传,2006,28(3):291-298. YANG S L,MAO H M,SHU W,et al.Melanin traits of Yunnan Black bone sheep and TYR gene polymorphism[J].Hereditas,2006,28(3):291-298.(in Chinese) [42] 孟浩浩.TYR、ASIP基因多态性与绵羊毛色相关的研究[D].石河子:石河子大学,2014. MENG H H.Association between the polymorphisms of TYR and ASIP genes and coat color in sheep[D].Shihezi:Shihezi University,2014.(in Chinese) [43] XUE L,LI Y,ZHAO B,et al.TRP-2 mediates coat color pig mentation in sheep skin[J].Molecular Medicine Reports,2018,17(4):5869-5877. [44] WU X,ZHANG Y,SHEN L,et al.A 6-bp deletion in exon 8 and two mutations in introns of TYRP1 are associated with blond coat color in Liangshan pigs[J].Gene,2016,578(1):132-136. [45] REN J,MAO H,ZHANG Z,et al.A 6-bp deletion in the TYRP1 gene causes the brown coloration phenotype in Chinese indigenous pigs[J].Heredity (Edinb),2011,106(5):862-868. [46] HAASE B,SIGNER-HASLER H,BINNS M M,et al.A accumulating mutations in series of haplotypes at the KIT and MITF loci are major determinants of white markings in Franches-Montagnes horses[J].PLoS One,2013,8(9):e75071. [47] NEGRO S,IMSLAND F,VALERA M,et al.Association analysis of KIT,MITF,and PAX3 variants with white markings in Spanish horses[J].Animal Genetics,2017,48(3):349-352. [48] YUSNIZAR Y,WILBE M,HERLINO A O,et al.Microphthalmia-associated transcription factor mutations are associated with white-spotted coat color in swamp buffalo[J].Animal Genetics,2015,46(6):676-682. [49] WANG C,WANG H,ZHANG Y,et al.Genome-wide analysis reveals artificial selection on coat colour and reproductive traits in Chinese domestic pigs[J].Molecular Ecology Resources,2015,15(2):414-424. [50] 张廷焕,柴捷,陈磊,等.猪MITF-M的转录调控分析[J].畜牧兽医学报,2018,49(11):2349-2358. ZHANG T H,CHAI J,CHEN L,et al.Transcriptional regulation analysis of pig MITF-M gene[J].Acta Veterinaria et Zootechnica Sinica,2018,49(11):2349-2358.(in Chinese) [51] LÜ M D,HAN X M,MA Y F,et al.Genetic variations associated with six-white-point coat pigmentation in Diannan smaller pigs[J].Scientific Reports,2016,6:27534. [52] 田雪.不同毛色羊蛇皮肤的全基因组表达谱分析和功能研究[D].太谷:山西农业大学,2013. TIAN X.Function and expression profiling of microRNAs in alpaca skin associated with coat color[D].Taigu:Shanxi Agricultural University,2013.(in Chinese) [53] WU Z,FU Y,CAO J,et al.Identification of differentially expressed miRNAs between white and black hair follicles by RNA-sequencing in the goat (Capra hircus)[J].International Journal of Molecular Sciences,2014,28;15(6):9531-9545. [54] 吴震洋,唐晓惠,付玉华,等.藏绵羊不同毛色皮肤组织miRNA表达谱及靶基因分析[J].中国农业科学,2018,51(2):351-362. WU Z Y,TANG X H,FU Y H,et al.Profiles of miRNA and target gene analysis with white and black skin tissues of the Tibetan sheep[J].Scientia Agricultura Sinica,2018,51(2):351-362.(in Chinese) [55] 孙武.山羊胎儿皮肤黑色素生成有关miRNA的筛选与鉴定[D].重庆:西南大学,2015. SUN W.Screening and identification of microRNA related to fetal skin melanogenesis in goat[D].Chongqing:Southwest University,2015.(in Chinese) [56] ZHU Z,HE J,JIA X,et al.microRNA-25 functions in regulation of pigmentation by targeting the transcription factor MITF in alpaca (Lama pacos) skin melanocytes[J].Domestic Animal Endocrinology,2010,38(3):200-209. [57] DONG C,WANG H,XUE L,et al.Coat color determination by miR-137 mediated down-regulation of microphthalmia-associated transcription factor in a mouse model[J].RNA,2012,18(9):1679-1686. [58] 杨怡.miRNA-340调节MITF分子参与UVB诱导色素合成的机制研究[D].北京:中国人民解放军总医院,2017. YANG Y.microRNA-340 is involved in UVB-induced pigmentation via regulating MITF[D].Beijing:Chinese PLA General Hospital,2017.(in Chinese) [59] GUO J,ZHANG J F,WANG W M,et al.microRNA-218 inhibits melanogenesis by directly suppressing microphthalmia-associated transcription factor expression[J].RNA Biology,2014,11(6):732-741. [60] QIAN H,YANG C,YANG Y.microRNA-26a inhibits the growth and invasiveness of malignant melanoma and directly targets on MITF gene[J].Cell Death Discovery,2017,3:17028. [61] YANG S,FAN R,SHI Z,et al.Identification of a novel microRNA important for melanogenesis in alpaca(Vicugna pacos)[J].Journal of Animal Sciences,2015,93(4):1622-1631. [62] ROESLER W J,PARK E A,MCFIE P J.Characterization of CCAAT/enhancer-binding protein as a cyclic AMP-responsive nuclear regulator[J].The Journal of Biological Chemistry,1998,273(24):14950-14957. [63] BUSCÀ R,BALLOTTI R.Cyclic AMP a key messenger in the regulation of skin pigmentation[J].Pigment Cell Research,2000,13(2):60-69. [64] 曾庆宝,范瑞文,张秋月,等.miR-324-3p通过调控MC1R基因影响黑色素的形成[J].畜牧兽医学报,2016,47(7):1381-1388. ZENG Q B,FAN R W,ZHANG Q Y,et al.The effect of miR-324-3p on melanin synthesis via MC1R gene[J].Acta Veterinaria et Zootechnica Sinica,2016,47(7):1381-1388.(in Chinese) [65] 武良琦,范瑞文,曾庆宝,等.miRNA-338-3p通过靶向抑制MC1R基因表达抑制羊驼黑色素细胞黑色素的生成[J].中国生物化学与分子生物学报,2017,33(6):624-629. WU L Q,FAN R W,ZENG Q B,et al.MicroRNA-338-3p inhibits melanogenesis in alpaca skin mmelanocytes by targeting MC1R[J].Chinese Journal of Biochemistry and Molecular Biology,2017,33(6):624-629.(in Chinese) [66] WANG P,ZHAO Y,FAN R,et al.microRNA-21a-5p functions on the regulation of melanogenesis by targeting sox5 in mouse skin melanocytes[J].International Journal of Molecular Sciences,2016,17(7):E959. [67] KIM K H,LEE T R,CHO E G.SH3BP4,a novel pigmentation gene,is inversely regulated by miR-125b and MITF[J].Expremental & Molecular Medicine,2017,49(8):e367. [68] WEBB A A,CULLEN C L.Coat color and coat color pattern-related neurologic and neuro-ophthalmic diseases[J].The Canadian Veterinary Journal,2010,51(6):653-657. [69] MAGONA J W,WALUBENGO J,OLAHO-MUKANI W,et al.Diagnostic value of rectal temperature of African cattle of variable coat colour infected with trypanosomes and tick-borne infections[J].Veterinary Parasitology,2009,160(3-4):301-305. [70] SAWALHA R M,BELL L,BROTHERSTONE S,et al.Scrapie-resistant sheep show certain coat colour characteristics[J].Genetics Research,2009,91(1):39-46. [71] FERNÁNDEZ-RODRÍGUEZ A,ESTELLÉ J,BLIN A,et al.KIT and melanoma predisposition in pigs:Sequence variants and association analysis[J].Animal Genetic,2014,45(3):445-448. |